3PIF

Crystal structure of the 5'->3' exoribonuclease Xrn1, E178Q mutant in Complex with Manganese

Summary for 3PIF

• Entry DOI: 10.2210/pdb3pif/pdb
• Related: 3PIE
• Descriptor: 5'->3' EXORIBONUCLEASE (xrn1), MANGANESE (II) ION (2 entities in total)
• Functional Keywords: beta berrel, tudor domain, chromo domain, mrna turnover, rrna processing, rna binding, dna binding, hydrolase
• Biological source: Kluyveromyces lactis (Yeast); More
• Cellular location: Cytoplasm : Q6CJ09
• Total number of polymer chains: 4
• Total formula weight: 529599.00

Authors

Chang, J.H.,Xiang, S.,Tong, L. (deposition date: 2010-11-06, release date: 2011-02-09, Last modification date: 2024-02-21)

• Primary citation: Chang, J.H.,Xiang, S.,Xiang, K.,Manley, J.L.,Tong, L.; Structural and biochemical studies of the 5' -> 3' exoribonuclease Xrn1.; Nat.Struct.Mol.Biol., 18:270-276, 2011; PubMed: 21297639; DOI: 10.1038/nsmb.1984

Experimental method

X-RAY DIFFRACTION (2.92 Å)