3PIF

Crystal structure of the 5'->3' exoribonuclease Xrn1, E178Q mutant in Complex with Manganese

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000956	biological_process	nuclear-transcribed mRNA catabolic process
A	0003676	molecular_function	nucleic acid binding
A	0004527	molecular_function	exonuclease activity
A	0008409	molecular_function	5'-3' exonuclease activity
B	0000956	biological_process	nuclear-transcribed mRNA catabolic process
B	0003676	molecular_function	nucleic acid binding
B	0004527	molecular_function	exonuclease activity
B	0008409	molecular_function	5'-3' exonuclease activity
C	0000956	biological_process	nuclear-transcribed mRNA catabolic process
C	0003676	molecular_function	nucleic acid binding
C	0004527	molecular_function	exonuclease activity
C	0008409	molecular_function	5'-3' exonuclease activity
D	0000956	biological_process	nuclear-transcribed mRNA catabolic process
D	0003676	molecular_function	nucleic acid binding
D	0004527	molecular_function	exonuclease activity
D	0008409	molecular_function	5'-3' exonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 1254

Chain	Residue
A	GLN178
A	ASP206
A	ASP208
A	ASP291

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN B 1254

Chain	Residue
B	GLN178
B	ASP206
B	ASP208
B	ASP291

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN C 1254

Chain	Residue
C	ASP206
C	ASP208
C	ASP291
C	GLN178

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN D 1254

Chain	Residue
D	ASP206
D	ASP208
D	ASP291

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