3PIF
Crystal structure of the 5'->3' exoribonuclease Xrn1, E178Q mutant in Complex with Manganese
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 5'->3' EXORIBONUCLEASE (xrn1) | polymer | 1155 | 132344.8 | 4 | UniProt (Q6CJ09) Pfam (PF03159) Pfam (PF17846) Pfam (PF18332) Pfam (PF18334) Pfam (PF18129) | Kluyveromyces lactis (Yeast) | |
| 2 | E, F, G, H (A, B, C, D) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) |
Sequence modifications
A, B, C, D: 1 - 463 (UniProt: Q6CJ09)
A, B, C, D: 503 - 984 (UniProt: Q6CJ09)
A, B, C, D: 1082 - 1245 (UniProt: Q6CJ09)
| PDB | External Database | Details |
|---|---|---|
| Gln 178 | Glu 178 | engineered mutation |
| Leu 1246 | - | expression tag |
| Glu 1247 | - | expression tag |
| His 1248 | - | expression tag |
| His 1249 | - | expression tag |
| His 1250 | - | expression tag |
| His 1251 | - | expression tag |
| His 1252 | - | expression tag |
| His 1253 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Unk 469 | - | SEE REMARK 999 |
| Unk 470 | - | SEE REMARK 999 |
| Unk 471 | - | SEE REMARK 999 |
| Unk 472 | - | SEE REMARK 999 |
| Unk 473 | - | SEE REMARK 999 |
| Unk 474 | - | SEE REMARK 999 |
| Unk 475 | - | SEE REMARK 999 |
| Unk 476 | - | SEE REMARK 999 |
| Unk 477 | - | SEE REMARK 999 |
| Unk 478 | - | SEE REMARK 999 |
| Unk 479 | - | SEE REMARK 999 |
| Unk 480 | - | SEE REMARK 999 |
| Unk 481 | - | SEE REMARK 999 |
| Unk 482 | - | SEE REMARK 999 |
| Unk 483 | - | SEE REMARK 999 |
| Unk 484 | - | SEE REMARK 999 |
| Unk 485 | - | SEE REMARK 999 |
| Unk 486 | - | SEE REMARK 999 |
| Unk 487 | - | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Unk 1036 | - | SEE REMARK 999 |
| Unk 1037 | - | SEE REMARK 999 |
| Unk 1038 | - | SEE REMARK 999 |
| Unk 1039 | - | SEE REMARK 999 |
| Unk 1040 | - | SEE REMARK 999 |
| Unk 1041 | - | SEE REMARK 999 |
| Unk 1042 | - | SEE REMARK 999 |
| Unk 1043 | - | SEE REMARK 999 |
| Unk 1044 | - | SEE REMARK 999 |
| Unk 1045 | - | SEE REMARK 999 |
| Unk 1046 | - | SEE REMARK 999 |
| Unk 1047 | - | SEE REMARK 999 |
| Unk 1048 | - | SEE REMARK 999 |
| Unk 1049 | - | SEE REMARK 999 |
| Unk 1050 | - | SEE REMARK 999 |
| Unk 1051 | - | SEE REMARK 999 |
| Unk 1052 | - | SEE REMARK 999 |
| Unk 1053 | - | SEE REMARK 999 |
| Unk 1054 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 529379.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 219.8 | |
| All* | Total formula weight | 529599.0 |
