4V1D
 
 | | Ternary complex among two human derived single chain antibody fragments and Cn2 toxin from scorpion Centruroides noxius. | | Descriptor: | BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT LR, HEAVY CHAIN, ... | | Authors: | Riano-Umbarila, L, Serrano-Posada, H, Rojas-Trejo, S, Rudino-Pinera, E, Becerril, B. | | Deposit date: | 2014-09-25 | | Release date: | 2015-10-07 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Optimal Neutralization of Centruroides Noxius Venom is Understood Through a Structural Complex between Two Antibody Fragments and the Cn2 Toxin.
J.Biol.Chem., 291, 2016
|
|
2SN3
 | | STRUCTURE OF SCORPION TOXIN VARIANT-3 AT 1.2 ANGSTROMS RESOLUTION | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, SCORPION NEUROTOXIN (VARIANT 3) | | Authors: | Zhao, B, Carson, M, Ealick, S.E, Bugg, C.E. | | Deposit date: | 1992-02-20 | | Release date: | 1994-01-31 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structure of scorpion toxin variant-3 at 1.2 A resolution.
J.Mol.Biol., 227, 1992
|
|
1FH3
 | |
5MOU
 | | NMR spatial structure of scorpion alpha-like toxin BeM9 | | Descriptor: | Alpha-mammal toxin BeM9 | | Authors: | Mineev, K.S, Kuldushev, N.A, Berkut, A.A, Grishin, E.V, Vassilevski, A.A, Arseniev, A.S. | | Deposit date: | 2016-12-14 | | Release date: | 2018-01-17 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Refined structure of BeM9 reveals arginine hand, an overlooked structural motif in scorpion toxins affecting sodium channels.
Proteins, 86, 2018
|
|
4AEI
 | | Crystal structure of the AaHII-Fab4C1 complex | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALPHA-MAMMAL TOXIN AAH2, CHLORIDE ION, ... | | Authors: | Fabrichny, I.P, Mondielli, G, Conrod, S, Martin-Eauclaire, M.F, Bourne, Y, Marchot, P. | | Deposit date: | 2012-01-10 | | Release date: | 2012-03-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Insights Into Antibody Sequestering and Neutralizing of Na+-Channel & [Alpha]-Type Modulator from Old-World Scorpion Venom
J.Biol.Chem., 287, 2012
|
|
8BO0
 | | Solution structure of Lqq4 toxin from Leiurus quinquestriatus quinquestriatus | | Descriptor: | Alpha-toxin Lqq4 | | Authors: | Mineev, K.S, Motov, V.V, Vassilevski, A.A, Chernykh, M.A, Kuzmenkov, A.I. | | Deposit date: | 2022-11-14 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-04 | | Method: | SOLUTION NMR | | Cite: | A scorpion toxin affecting sodium channels shows double cis-trans isomerism.
Febs Lett., 597, 2023
|
|
6THI
 | | Solution structure of MeuNaTxalpha-1 toxin from Mesobuthus Eupeus | | Descriptor: | Sodium channel neurotoxin MeuNaTxalpha-1 | | Authors: | Mineev, K.S, Kuzmenkov, A.I, Khusainov, G.A, Arseniev, A.S, Vassilevski, A.A. | | Deposit date: | 2019-11-20 | | Release date: | 2020-12-02 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structure of MeuNaTx alpha-1 toxin from scorpion venom highlights the importance of the nest motif.
Proteins, 2021
|
|
5CY0
 | | Total Chemical Synthesis, Covalent Structure Verification, and X-ray Structure of Bioactive Ts3 Toxin by Racemic Protein Crystallography | | Descriptor: | GLYCEROL, Ts3 Toxin | | Authors: | Dang, B, Kubota, T, Mandal, K, Correa, A.M, Bezanilla, F, Kent, S.B. | | Deposit date: | 2015-07-29 | | Release date: | 2016-06-01 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin.
Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
6VXW
 | |
1VNA
 | |
1VNB
 | |
4HHF
 | | Crystal Structure of chemically synthesized scorpion alpha-toxin OD1 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-toxin OD1 | | Authors: | Wang, C.I.A, Lewis, R.J, Alewood, P.F, Durek, T. | | Deposit date: | 2012-10-09 | | Release date: | 2013-04-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Chemical engineering and structural and pharmacological characterization of the alpha-scorpion toxin OD1.
Acs Chem.Biol., 8, 2013
|
|
4KYP
 | | Beta-Scorpion Toxin folded in the periplasm of E.coli | | Descriptor: | Beta-insect excitatory toxin Bj-xtrIT, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL | | Authors: | O'Reilly, A.O, Cole, A.R, Lopes, J.L, Lampert, A, Wallace, B.A. | | Deposit date: | 2013-05-29 | | Release date: | 2014-02-12 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Chaperone-mediated native folding of a beta-scorpion toxin in the periplasm of Escherichia coli.
Biochim.Biophys.Acta, 1840, 2014
|
|
2YEO
 | | A39L mutation of scorpion toxin lqh-alpha-it | | Descriptor: | 1,2-ETHANEDIOL, ALPHA-INSECT TOXIN LQHAIT, CHLORIDE ION, ... | | Authors: | Frolow, F, Kahn, R, Gurevitz, M. | | Deposit date: | 2011-03-28 | | Release date: | 2011-04-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.08 Å) | | Cite: | Crystal Structures of Scorpion Alpha-Toxinsmutants Reveal Conformational Constraints that Dictate Preference for Mammalian Brain Voltage-Gated Na- Channels
To be Published
|
|
2YC1
 | | Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann | | Descriptor: | BETA-MAMMAL TOXIN CN2, GLYCEROL, SINGLE CHAIN ANTIBODY FRAGMENT 9004G | | Authors: | Canul-Tec, J.C, Riano-Umbarila, L, Rudino-Pinera, E, Becerril, B, Possani, L.D, Torres-Larios, A. | | Deposit date: | 2011-03-10 | | Release date: | 2011-04-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment.
J.Biol.Chem., 286, 2011
|
|
2YBR
 | | Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann | | Descriptor: | BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT 9004G | | Authors: | Canul-Tec, J.C, Riano-Umbarila, L, Rudino-Pinera, E, Becerril, B, Possani, L.D, Torres-Larios, A. | | Deposit date: | 2011-03-09 | | Release date: | 2011-04-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment
J.Biol.Chem., 286, 2011
|
|
2E0H
 | |
2ASC
 | | Scorpion toxin LQH-alpha-IT | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, ETHANOL, ... | | Authors: | Kahn, R, Karbat, I, Gurevitz, M, Frolow, F. | | Deposit date: | 2005-08-23 | | Release date: | 2006-09-05 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant
To be Published
|
|
2B3C
 | | SOLUTION STRUCTURE OF A BETA-NEUROTOXIN FROM THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING | | Descriptor: | PROTEIN (NEUROTOXIN CSE-I) | | Authors: | Jablonsky, M.J, Jackson, P.L, Trent, J.O, Watt, D.D, Krishna, N.R. | | Deposit date: | 1998-12-09 | | Release date: | 1998-12-16 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a beta-neurotoxin from the New World scorpion Centruroides sculpturatus Ewing.
Biochem.Biophys.Res.Commun., 254, 1999
|
|
1PE4
 | | SOLUTION STRUCTURE OF TOXIN CN12 FROM CENTRUROIDES NOXIUS ALFA SCORPION TOXIN ACTING ON SODIUM CHANNELS. NMR STRUCTURE | | Descriptor: | Neurotoxin Cn11 | | Authors: | Del Rio-Portilla, F, Hernandez-Marin, E, Pimienta, G, Coronas, F.V, Zamudio, F.Z, Rodrguez de la Vega, R.C, Wanke, E, Possani, L.D. | | Deposit date: | 2003-05-21 | | Release date: | 2004-05-25 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity.
Eur.J.Biochem., 271, 2004
|
|
1NRB
 | |
1NH5
 | | AUTOMATIC ASSIGNMENT OF NMR DATA AND DETERMINATION OF THE PROTEIN STRUCTURE OF A NEW WORLD SCORPION NEUROTOXIN USING NOAH/DIAMOD | | Descriptor: | Neurotoxin 5 | | Authors: | Xu, Y, Jablonsky, M.J, Jackson, P.L, Krishna, N.R, Braun, W. | | Deposit date: | 2002-12-18 | | Release date: | 2003-01-07 | | Last modified: | 2018-01-24 | | Method: | SOLUTION NMR | | Cite: | Automatic assignment of NOESY Cross peaks and determination of the protein structure of a new world scorpion neurotoxin Using NOAH/DIAMOD
J.Magn.Reson., 148, 2001
|
|
1NRA
 | |
1OMY
 | | Crystal Structure of a Recombinant alpha-insect Toxin BmKaIT1 from the scorpion Buthus martensii Karsch | | Descriptor: | ACETIC ACID, Alpha-neurotoxin TX12, CHLORIDE ION | | Authors: | Huang, Y, Huang, Q, Chen, H, Tang, Y, Miyake, H, Kusunoki, M. | | Deposit date: | 2003-02-26 | | Release date: | 2003-09-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystallization and preliminary crystallographic study of rBmKalphaIT1, a recombinant alpha-insect toxin from the scorpion Buthus martensii Karsch.
Acta Crystallogr.,Sect.D, 59, 2003
|
|
1NPI
 | | Tityus Serrulatus Neurotoxin (Ts1) at atomic resolution | | Descriptor: | PHOSPHATE ION, Toxin VII | | Authors: | Pinheiro, C.B, Marangoni, S, Toyama, M.H, Polikarpov, I. | | Deposit date: | 2003-01-17 | | Release date: | 2003-02-25 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.16 Å) | | Cite: | Structural analysis of Tityus serrulatus Ts1 neurotoxin at atomic resolution: insights into interactions with Na+ channels.
Acta Crystallogr.,Sect.D, 59, 2003
|
|
