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PDB: 519 results

8C3B
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BU of 8c3b by Molmil
X-ray structure of RNase A upon reaction with a Ruthenium(II)-arene Complexed with Glycosylated Carbene Ligands (5)
Descriptor: (1,3-dimethyl-2~{H}-imidazol-2-yl)-oxidanyl-oxidanylidene-ruthenium, (1,3-dimethylimidazol-1-ium-2-yl)-tetrakis(oxidanyl)ruthenium, (1,3-dimethylimidazol-1-ium-2-yl)-tris(oxidanyl)ruthenium, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2022-12-23
Release date:2024-01-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Ruthenium(II)–Arene Complexes with Glycosylated NHC-Carbene Co-Ligands: Synthesis, Hydrolytic Behavior, and Binding to Biological Molecules
Organometallics, 42, 2023
5E5E
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BU of 5e5e by Molmil
X-ray structure of the adduct formed in the reaction between RNase A and a neutral organometallic derivative [Pt(pbi)(Me)(DMSO)], pbi=2-(2'-pyridil)benzimidazole (compound 3)
Descriptor: DIMETHYL SULFOXIDE, PLATINUM (II) ION, Ribonuclease pancreatic
Authors:Merlino, A.
Deposit date:2015-10-08
Release date:2015-12-09
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Cytotoxic properties of a new organometallic platinum(ii) complex and its gold(i) heterobimetallic derivatives.
Dalton Trans, 45, 2015
9FYW
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BU of 9fyw by Molmil
X-ray structure of the adduct formed upon reaction of RNase A with [Ru2Cl(D-p-CNPhF)(O2CCH3)3]
Descriptor: 4-[11-(4-cyanophenyl)-1,5-bis($l^{1}-oxidanyl)-3,7-dimethyl-2,4,6,8-tetraoxa-9,11-diaza-1$l^{5},5$l^{5}-diruthenatricyclo[3.3.3.0^{1,5}]undecan-9-yl]benzenecarbonitrile, Ribonuclease pancreatic, SULFATE ION
Authors:Teran, A, Ferraro, G, Merlino, A.
Deposit date:2024-07-04
Release date:2024-11-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Exchange of equatorial ligands in protein-bound paddlewheel Ru25+ complexes: new insights from X-ray crystallography and quantum chemistry
Inorg Chem Front, 11, 2024
7NPM
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BU of 7npm by Molmil
X-ray structure of the adduct formed upon reaction of oxaliplatin with human angiogenin
Descriptor: Angiogenin, D(-)-TARTARIC ACID, PLATINUM (II) ION
Authors:Ferraro, G, Merlino, A.
Deposit date:2021-02-27
Release date:2022-03-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Oxaliplatin inhibits angiogenin proliferative and cell migration effects in prostate cancer cells.
J.Inorg.Biochem., 226, 2022
3A1R
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BU of 3a1r by Molmil
Neutron crystal structure analysis of bovine pancreatic ribonuclease A
Descriptor: Ribonuclease pancreatic
Authors:Yagi, D, Tanaka, I, Niimura, N.
Deposit date:2009-04-21
Release date:2009-09-01
Last modified:2024-11-06
Method:NEUTRON DIFFRACTION (1.7 Å)
Cite:A neutron crystallographic analysis of phosphate-free ribonuclease A at 1.7 A resolution
Acta Crystallogr.,Sect.D, 65, 2009
6GOK
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BU of 6gok by Molmil
X-ray structure of the adduct formed upon reaction of bovine pancreatic ribonuclease with a Pd(II) complex bearing N,N-pyridylbenzimidazole derivative with an alkylated sulphonate side chain
Descriptor: N,N-pyridylbenzimidazole derivative-Pd complex, PALLADIUM ION, Ribonuclease pancreatic
Authors:Merlino, A, Ferraro, G.
Deposit date:2018-06-01
Release date:2018-07-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Exploring the interactions between model proteins and Pd(ii) or Pt(ii) compounds bearing charged N,N-pyridylbenzimidazole bidentate ligands by X-ray crystallography.
Dalton Trans, 47, 2018
7TY1
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BU of 7ty1 by Molmil
Crystal structure of apo eosinophil cationic protein (ribonuclease 3) from Macaca fascicularis (MfECP)
Descriptor: CITRIC ACID, DI(HYDROXYETHYL)ETHER, Eosinophil cationic protein, ...
Authors:Tran, T.T.Q, Pham, N.T.H, Calmettes, C, Doucet, N.
Deposit date:2022-02-11
Release date:2023-08-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases.
J.Biol.Chem., 300, 2024
8AF0
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BU of 8af0 by Molmil
Crystal structure of human angiogenin and RNA duplex
Descriptor: Angiogenin, GLYCEROL, RNA (5'-R(*GP*CP*CP*CP*GP*CP*CP*UP*GP*UP*CP*AP*CP*GP*CP*GP*GP*GP*C)-3')
Authors:Sievers, K, Ficner, R.
Deposit date:2022-07-15
Release date:2022-09-14
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structure of angiogenin dimer bound to double-stranded RNA.
Acta Crystallogr.,Sect.F, 78, 2022
8F5X
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BU of 8f5x by Molmil
Crystal structure of human eosinophil-derived neurotoxin (EDN, ribonuclease 2) in complex with 5'-adenosine monophosphate (AMP)
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Non-secretory ribonuclease, ...
Authors:Tran, T.T.Q, Pham, N.T.H, Calmettes, C, Doucet, N.
Deposit date:2022-11-15
Release date:2023-11-29
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases.
J.Biol.Chem., 300, 2024
4G8Y
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BU of 4g8y by Molmil
Crystal structure of Ribonuclease A in complex with 5b
Descriptor: 1-{[1-(alpha-L-arabinofuranosyl)-1H-1,2,3-triazol-4-yl]methyl}-5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine, Ribonuclease pancreatic
Authors:Chatzileontiadou, D.S.M, Kantsadi, A.L, Leonidas, D.D.
Deposit date:2012-07-23
Release date:2012-11-21
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation.
Bioorg.Med.Chem., 20, 2012
4G90
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BU of 4g90 by Molmil
Crystal structure of Ribonuclease A in complex with 5e
Descriptor: 1-{[1-(alpha-L-arabinofuranosyl)-1H-1,2,3-triazol-4-yl]methyl}-5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidine, Ribonuclease pancreatic
Authors:Chatzileontiadou, D.S.M, Kantsadi, A.L, Leonidas, D.D.
Deposit date:2012-07-23
Release date:2012-11-21
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation.
Bioorg.Med.Chem., 20, 2012
1EIC
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BU of 1eic by Molmil
CRYSTAL STRUCTURE OF F120A MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A
Descriptor: RIBONUCLEASE A
Authors:Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
Deposit date:2000-02-25
Release date:2002-02-13
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution.
Protein Sci., 11, 2002
1EOW
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BU of 1eow by Molmil
CRYSTAL STRUCTURE OF RIBONUCLEASE A COMPLEXED WITH URIDYLYL(2',5')GUANOSINE (NON-PRODUCTIVE BINDING)
Descriptor: RIBONUCLEASE PANCREATIC, SULFATE ION, URIDYLYL-2'-5'-PHOSPHO-GUANOSINE
Authors:Vitagliano, L, Merlino, A, Zagari, A, Mazzarella, L.
Deposit date:2000-03-24
Release date:2000-11-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2',5')guanosine.
Protein Sci., 9, 2000
5RSA
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BU of 5rsa by Molmil
COMPARISON OF TWO INDEPENDENTLY REFINED MODELS OF RIBONUCLEASE-A
Descriptor: PHOSPHATE ION, RIBONUCLEASE A
Authors:Wlodawer, A.
Deposit date:1985-04-29
Release date:1985-07-17
Last modified:2024-11-06
Method:NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION
Cite:Comparison of Two Independently Refined Models of Ribonuclease-A
Acta Crystallogr.,Sect.B, 42, 1986
6RSA
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BU of 6rsa by Molmil
NUCLEAR MAGNETIC RESONANCE AND NEUTRON DIFFRACTION STUDIES OF THE COMPLEX OF RIBONUCLEASE*A WITH URIDINE VANADATE, A TRANSITION-STATE ANALOGUE
Descriptor: RIBONUCLEASE A, URIDINE-2',3'-VANADATE
Authors:Wlodawer, A.
Deposit date:1986-02-25
Release date:1986-05-07
Last modified:2024-10-30
Method:NEUTRON DIFFRACTION (2 Å), SOLUTION NMR
Cite:Nuclear magnetic resonance and neutron diffraction studies of the complex of ribonuclease A with uridine vanadate, a transition-state analogue.
Biochemistry, 24, 1985
8QEW
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BU of 8qew by Molmil
Eosinophil Derived Neurotoxin/RNase 2 in complex with Tartrate
Descriptor: L(+)-TARTARIC ACID, Non-secretory ribonuclease
Authors:Li, J, Kang, X, Prats-Ejarque, G, Boix, E.
Deposit date:2023-09-01
Release date:2024-09-11
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Eosinophil Derived Neurotoxin/RNase 2 in complex with Tartrate
To Be Published
9JWH
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BU of 9jwh by Molmil
Crystal structure of native bovine pancreatic RNAs A
Descriptor: CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION
Authors:Ahmad, M.S, Shah, N.
Deposit date:2024-10-10
Release date:2024-12-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Cyanide mediated conformational changes resulted in the displacement of sulfate ion from the active site of bovine pancreatic ribonuclease A.
Biochem.Biophys.Res.Commun., 736, 2024
9JWD
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BU of 9jwd by Molmil
Crystal structure of RNAs A treated with sodium cyanide
Descriptor: CHLORIDE ION, CYANIDE ION, GLYCEROL, ...
Authors:Ahmad, M.S, Shah, N.
Deposit date:2024-10-10
Release date:2024-12-04
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Cyanide mediated conformational changes resulted in the displacement of sulfate ion from the active site of bovine pancreatic ribonuclease A.
Biochem.Biophys.Res.Commun., 736, 2024
4G8V
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BU of 4g8v by Molmil
Crystal structure of Ribonuclease A in complex with 5a
Descriptor: 1-{[1-(alpha-L-arabinofuranosyl)-1H-1,2,3-triazol-4-yl]methyl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidine, Ribonuclease pancreatic
Authors:Chatzileontiadou, D.S.M, Kantsadi, A.L, Leonidas, D.D.
Deposit date:2012-07-23
Release date:2012-11-21
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation.
Bioorg.Med.Chem., 20, 2012
6XVX
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BU of 6xvx by Molmil
X-ray structure obtained upon reaction of dirhodium tetraacetate with RNase A (high resolution)
Descriptor: ACETATE ION, RHODIUM(III) ION, Ribonuclease pancreatic
Authors:Merlino, A, Ferraro, G.
Deposit date:2020-01-22
Release date:2020-02-19
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Protein interactions of dirhodium tetraacetate: a structural study.
Dalton Trans, 49, 2020
8R5V
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BU of 8r5v by Molmil
Crystal structure of bovine pancreatic ribonuclease A in complex with [Sp-PS]-mU-dT dinucleotide
Descriptor: 1-[(2~{R},4~{S},5~{R})-5-[[[(2~{R},6~{S})-2-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-6-(hydroxymethyl)morpholin-4-yl]-oxidanyl-phosphinothioyl]oxymethyl]-4-oxidanyl-oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione, DICHLORO-ACETIC ACID, Ribonuclease pancreatic
Authors:Dolot, R, Jastrzebska, K, Antonczyk, P.
Deposit date:2023-11-17
Release date:2023-12-06
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:P-Stereodefined morpholino dinucleoside 3',5'-phosphorothioates.
Org.Biomol.Chem., 22, 2024
6XW0
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BU of 6xw0 by Molmil
X-ray structure obtained upon reaction of dirhodium tetraacetate with RNase A (low resolution)
Descriptor: ACETATE ION, RHODIUM(III) ION, Ribonuclease pancreatic
Authors:Merlino, A, Ferraro, G.
Deposit date:2020-01-22
Release date:2020-02-19
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Protein interactions of dirhodium tetraacetate: a structural study.
Dalton Trans, 49, 2020
5RAT
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BU of 5rat by Molmil
Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 TO 320 K
Descriptor: RIBONUCLEASE A
Authors:Tiltonjunior, R.F, Dewan, J.C, Petsko, G.A.
Deposit date:1991-08-13
Release date:1993-07-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K.
Biochemistry, 31, 1992
6MV6
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BU of 6mv6 by Molmil
Crystal structure of RNAse 6
Descriptor: PHOSPHATE ION, Ribonuclease K6
Authors:Couture, J.-F, Doucet, N.
Deposit date:2018-10-24
Release date:2019-11-13
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Insights into Structural and Dynamical Changes Experienced by Human RNase 6 upon Ligand Binding.
Biochemistry, 59, 2020
7Z6G
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BU of 7z6g by Molmil
X-ray structure of the adduct obtained upon reaction of [Rh2(OCOCH3)(OCOCF3)3] with RNase A (2)
Descriptor: (mi2-acetato-O, O')-hexaaquo-dirhodium (II), Rhodium, ...
Authors:Loreto, D, Merlino, A.
Deposit date:2022-03-11
Release date:2023-03-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Reactivity of a fluorine-containing dirhodium tetracarboxylate compound with proteins
Dalton Trans, 51, 2022

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