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PDB: 221 results

8TOF
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BU of 8tof by Molmil
Rpd3S bound to an H3K36Cme3 modified nucleosome
Descriptor: Chromatin modification-related protein EAF3, DNA (176-MER), Histone H2A, ...
Authors:Markert, J.W, Vos, S.M, Farnung, L.
Deposit date:2023-08-03
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of the complete Saccharomyces cerevisiae Rpd3S-nucleosome complex.
Nat Commun, 14, 2023
7VDT
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BU of 7vdt by Molmil
The motor-nucleosome module of human chromatin remodeling PBAF-nucleosome complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (207-MER), ...
Authors:Chen, Z.C, Chen, K.J, Yuan, J.J.
Deposit date:2021-09-07
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Nature, 605, 2022
1AOI
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BU of 1aoi by Molmil
COMPLEX BETWEEN NUCLEOSOME CORE PARTICLE (H3,H4,H2A,H2B) AND 146 BP LONG DNA FRAGMENT
Descriptor: HISTONE H2A, HISTONE H2B, HISTONE H3, ...
Authors:Luger, K, Maeder, A.W, Richmond, R.K, Sargent, D.F, Richmond, T.J.
Deposit date:1997-07-03
Release date:1998-09-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the nucleosome core particle at 2.8 A resolution.
Nature, 389, 1997
5MLU
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BU of 5mlu by Molmil
Crystal structure of the PFV GAG CBS bound to a mononucleosome
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B, ...
Authors:Pye, V.E, Maskell, D.P, Lesbats, P, Cherepanov, P.
Deposit date:2016-12-07
Release date:2017-05-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for spumavirus GAG tethering to chromatin.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8V6V
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BU of 8v6v by Molmil
Cryo-EM structure of doubly-bound SNF2h-nucleosome complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Histone H2A type 1, Histone H2B, ...
Authors:Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y.
Deposit date:2023-12-03
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Nat Commun, 15, 2024
8V4Y
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BU of 8v4y by Molmil
Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h at inactive SHL2 (conformation 1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Histone H2A type 1, ...
Authors:Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y.
Deposit date:2023-11-29
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Nat Commun, 15, 2024
6WZ9
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BU of 6wz9 by Molmil
Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin
Descriptor: DNA, Histone H2A, Histone H2B 1.1, ...
Authors:Halic, M, Bilokapic, S.
Deposit date:2020-05-13
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Nature, 585, 2020
7XFN
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BU of 7xfn by Molmil
Structure of nucleosome-DI complex (-55I, Apo state)
Descriptor: DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Zheng, L, Tsai, B, Gao, N.
Deposit date:2022-04-01
Release date:2023-04-19
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
7XFL
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BU of 7xfl by Molmil
Structure of nucleosome-AAG complex (A-53I, free state)
Descriptor: DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Zheng, L, Tsai, B, Gao, N.
Deposit date:2022-04-01
Release date:2023-04-19
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
7ENN
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BU of 7enn by Molmil
The structure of ALC1 bound to the nucleosome
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromodomain-helicase-DNA-binding protein 1-like, ...
Authors:Chen, Z.C, Chen, K.J, Wang, L.
Deposit date:2021-04-18
Release date:2021-07-14
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome.
Nat Commun, 12, 2021
5E5A
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BU of 5e5a by Molmil
Crystal structure of the chromatin-tethering domain of Human cytomegalovirus IE1 protein bound to the nucleosome core particle
Descriptor: C-terminal domain of Regulatory protein IE1, DNA (146-MER), Histone H2A, ...
Authors:Fang, Q, Chen, P, Wang, M, Fang, J, Yang, N, Li, G, Xu, R.M.
Deposit date:2015-10-08
Release date:2016-02-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.809 Å)
Cite:Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5, 2016
5DNM
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BU of 5dnm by Molmil
Nucleosome core particle containing adducts of ruthenium(II)-toluene PTA complex
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Adhireksan, Z, Muhammad, R, Davey, C.A.
Deposit date:2015-09-10
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Allosteric cross-talk in chromatin can mediate drug-drug synergy
Nat Commun, 8, 2017
4J8X
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BU of 4j8x by Molmil
X-ray structure of NCP145 with bound chlorido(eta-6-p-cymene)(N-fluorophenyl-2-pyridinecarbothioamide)ruthenium(II)
Descriptor: DNA, Histone H2A, Histone H2B 1.1, ...
Authors:Adhireksan, Z, Davey, C.A.
Deposit date:2013-02-15
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
8KD5
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BU of 8kd5 by Molmil
Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class2
Descriptor: 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ...
Authors:Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Chang, X, Chao, W.C.H, He, J.
Deposit date:2023-08-09
Release date:2023-09-13
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Cell Res., 33, 2023
7NKX
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BU of 7nkx by Molmil
RNA polymerase II-Spt4/5-nucleosome-Chd1 structure
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin elongation factor SPT4, ...
Authors:Farnung, L, Ochmann, M, Engeholm, M, Cramer, P.
Deposit date:2021-02-19
Release date:2021-08-25
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Nat.Struct.Mol.Biol., 28, 2021
8V7L
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BU of 8v7l by Molmil
Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h at inactive SHL2 (conformation 2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Histone H2A type 1, Histone H2B, ...
Authors:Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y.
Deposit date:2023-12-04
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Nat Commun, 15, 2024
1P3M
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BU of 1p3m by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
Deposit date:2003-04-17
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
7OHA
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BU of 7oha by Molmil
nucleosome with TBP and TFIIA bound at SHL +2
Descriptor: DNA (122-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Wang, H, Cramer, P.
Deposit date:2021-05-09
Release date:2021-07-28
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
8SIY
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BU of 8siy by Molmil
Origin Recognition Complex Associated (ORCA) protein bound to H4K20me3-nucleosome
Descriptor: Histone H2A, Histone H2B, Histone H3.2, ...
Authors:Bleichert, F, Ekundayo, B.E.
Deposit date:2023-04-17
Release date:2023-08-02
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:A dual role for the chromatin reader ORCA/LRWD1 in targeting the origin recognition complex to chromatin.
Embo J., 42, 2023
1P3K
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BU of 1p3k by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
Deposit date:2003-04-17
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
1P3F
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BU of 1p3f by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
Deposit date:2003-04-17
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
3KUY
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BU of 3kuy by Molmil
DNA Stretching in the Nucleosome Facilitates Alkylation by an Intercalating Antitumor Agent
Descriptor: 2-[(2R)-oxiran-2-ylmethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione, DNA (145-MER), Histone H2A, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2009-11-28
Release date:2010-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:DNA stretching in the nucleosome facilitates alkylation by an intercalating antitumour agent
Nucleic Acids Res., 38, 2010
7XFC
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BU of 7xfc by Molmil
Structure of nucleosome-DI complex (-30I, Apo state)
Descriptor: DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Zheng, L, Tsai, B, Gao, N.
Deposit date:2022-04-01
Release date:2023-04-19
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
7XFI
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BU of 7xfi by Molmil
Structure of nucleosome-DI complex (-50I, Apo state)
Descriptor: DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Zheng, L, Tsai, B, Gao, N.
Deposit date:2022-04-01
Release date:2023-04-19
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
7XFH
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BU of 7xfh by Molmil
Structure of nucleosome-AAG complex (A-30I, post-catalytic state)
Descriptor: DNA (152-MER), DNA-3-methyladenine glycosylase, Histone H2A type 1, ...
Authors:Zheng, L, Tsai, B, Gao, N.
Deposit date:2022-04-01
Release date:2023-04-19
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023

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