8Z1L
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![BU of 8z1l by Molmil](/molmil-images/mine/8z1l) | Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant atomoxetine in an outward-open state at resolution of 3.4 angstrom. | Descriptor: | (3R)-N-methyl-3-(2-methylphenoxy)-3-phenyl-propan-1-amine, CHLORIDE ION, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2024-04-11 | Release date: | 2024-07-31 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature, 632, 2024
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8HFI
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![BU of 8hfi by Molmil](/molmil-images/mine/8hfi) | Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant desipramine in an inward-open state at resolution of 2.5 angstrom. | Descriptor: | 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, CHLORIDE ION, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2022-11-10 | Release date: | 2024-05-15 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature, 632, 2024
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8HFG
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![BU of 8hfg by Molmil](/molmil-images/mine/8hfg) | Cryo-EM structure of human norepinephrine transporter NET in the presence of dopamine in an inward-open state at resolution of 3.0 angstrom. | Descriptor: | CHLORIDE ION, L-DOPAMINE, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2022-11-10 | Release date: | 2024-05-15 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature, 632, 2024
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8WGR
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![BU of 8wgr by Molmil](/molmil-images/mine/8wgr) | Cryo-EM structure of inward-open state human norepinephrine transporter NET bound with antidepressant desipramine in KCl condition. | Descriptor: | 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2023-09-22 | Release date: | 2024-07-31 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature, 632, 2024
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8WGX
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![BU of 8wgx by Molmil](/molmil-images/mine/8wgx) | Cryo-EM structure of inward-open state human norepinephrine transporter NET bound with norepinephrine in nanodisc. | Descriptor: | L-NOREPINEPHRINE, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2023-09-22 | Release date: | 2024-07-31 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature, 632, 2024
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8I3V
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![BU of 8i3v by Molmil](/molmil-images/mine/8i3v) | Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant escitalopram in an inward-open state at resolution of 2.85 angstrom. | Descriptor: | (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, CHLORIDE ION, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2023-01-18 | Release date: | 2024-07-03 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature, 632, 2024
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8HFE
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![BU of 8hfe by Molmil](/molmil-images/mine/8hfe) | Cryo-EM structure of human norepinephrine transporter NET in an inward-open state at resolution of 2.5 angstrom | Descriptor: | CHLORIDE ION, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2022-11-10 | Release date: | 2024-05-15 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature, 632, 2024
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8HFF
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![BU of 8hff by Molmil](/molmil-images/mine/8hff) | Cryo-EM structure of human norepinephrine transporter NET in the presence of norepinephrine in an inward-open state at resolution of 2.9 angstrom. | Descriptor: | L-NOREPINEPHRINE, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2022-11-10 | Release date: | 2024-05-15 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature, 632, 2024
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8HFL
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![BU of 8hfl by Molmil](/molmil-images/mine/8hfl) | Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant bupropion in an inward-open state at resolution of 3.0 angstrom. | Descriptor: | Bupropion, CHLORIDE ION, Sodium-dependent noradrenaline transporter | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | Deposit date: | 2022-11-11 | Release date: | 2024-05-15 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature, 632, 2024
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