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PDB: 25 件
1F6A
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Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)ri(alpha)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
著者Garman, S.C, Wurzburg, B.A, Tarchevskaya, S.S, Kinet, J.P, Jardetzky, T.S.
登録日2000-06-20
公開日2000-07-20
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc (epsilon) RI (alpha).
Nature, 406, 2000
1GPZ
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BU of 1gpz by Molmil
THE CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC DOMAIN OF COMPLEMENT PROTEASE C1R
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C1R COMPONENT, ...
著者Budayova-Spano, M, Fontecilla-Camps, J.C, Gaboriaud, C.
登録日2001-11-15
公開日2002-07-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Crystal Structure of the Zymogen Catalytic Domain of Complement Protease C1R Reveals that a Disruptive Mechanical Stress is Required to Trigger Activation of the C1 Complex.
Embo J., 21, 2002
2J0G
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BU of 2j0g by Molmil
L-ficolin complexed to N-acetyl-mannosamine
分子名称: 2-acetamido-2-deoxy-alpha-D-mannopyranose, CALCIUM ION, FICOLIN-2, ...
著者Garlatti, V, Gaboriaud, C.
登録日2006-08-03
公開日2007-01-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins.
Embo J., 26, 2007
2Q7N
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BU of 2q7n by Molmil
Crystal structure of Leukemia inhibitory factor in complex with LIF receptor (domains 1-5)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Huyton, T, Zhang, J.G, Nicola, N.A, Garrett, T.P.J.
登録日2007-06-07
公開日2007-07-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor.
Proc.Natl.Acad.Sci.USA, 104, 2007
3E0G
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BU of 3e0g by Molmil
Structure of the Leukemia Inhibitory Factor Receptor (LIF-R) domains D1-D5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Leukemia inhibitory factor receptor, ...
著者Lupardus, P.J, Garcia, K.C.
登録日2008-07-31
公開日2008-09-23
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex.
Mol.Cell, 31, 2008
3RJD
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BU of 3rjd by Molmil
Crystal structure of Fc RI and its implication to high affinity immunoglobulin G binding
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ...
著者Lu, J, Sun, P.D.
登録日2011-04-15
公開日2011-09-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of Fc gamma receptor I and its implication in high affinity gamma-immunoglobulin binding.
J.Biol.Chem., 286, 2011
4BOE
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BU of 4boe by Molmil
Japanin from Rhipicephalus appendiculatus bound to cholesterol: Tetragonal crystal form
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Roversi, P, Johnson, S, Preston, S, Austyn, J.M, Nuttall, P, Lea, S.M.
登録日2013-05-19
公開日2014-05-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks.
Sci Rep, 7, 2017
4BQU
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Japanin from Rhipicephalus appendiculatus bound to cholesterol: Orthorhombic crystal form
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Roversi, P, Johnson, S, Preston, S, Austyn, J.M, Nuttall, P, Lea, S.M.
登録日2013-06-02
公開日2014-06-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks.
Sci Rep, 7, 2017
4EWS
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BU of 4ews by Molmil
Crystal structure of cholesteryl ester transfer protein in complex with inhibitors
分子名称: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CETP, CHLORIDE ION, ...
著者Liu, S, Qiu, X.
登録日2012-04-27
公開日2012-09-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystal structures of cholesteryl ester transfer protein in complex with inhibitors.
J.Biol.Chem., 287, 2012
4F2A
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BU of 4f2a by Molmil
Crystal structure of cholestryl esters transfer protein in complex with inhibitors
分子名称: (2R)-3-{[4-(4-chloro-3-ethylphenoxy)pyrimidin-2-yl][3-(1,1,2,2-tetrafluoroethoxy)benzyl]amino}-1,1,1-trifluoropropan-2-ol, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHLORIDE ION, ...
著者Liu, S, Qiu, X.
登録日2012-05-07
公開日2012-09-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Crystal structures of cholesteryl ester transfer protein in complex with inhibitors.
J.Biol.Chem., 287, 2012
4MQE
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BU of 4mqe by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor in the apo form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ...
著者Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
登録日2013-09-16
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MQF
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Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist 2-hydroxysaclofen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxysaclofen, Gamma-aminobutyric acid type B receptor subunit 1, ...
著者Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
登録日2013-09-16
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MR7
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BU of 4mr7 by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP54626
分子名称: (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ...
著者Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
登録日2013-09-17
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MR9
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BU of 4mr9 by Molmil
Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist SCH50911
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ...
著者Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R.
登録日2013-09-17
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4NYT
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BU of 4nyt by Molmil
L-Ficolin Complexed to Phosphocholine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
著者Laffly, E, Gaboriaud, C, Martin, L, Thielens, N.
登録日2013-12-11
公開日2014-10-29
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Human L-ficolin recognizes phosphocholine moieties of pneumococcal teichoic Acid
J.Immunol., 193, 2014
5AM8
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BU of 5am8 by Molmil
Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with amyloid-beta 4-10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, ...
著者Masuyer, G, Larmuth, K.M, Douglas, R.G, Sturrock, E.D, Acharya, K.R.
登録日2015-03-10
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Kinetic and Structural Characterisation of Amyloid-Beta Metabolism by Human Angiotensin-1- Converting Enzyme (Ace)
FEBS J., 283, 2016
5AMA
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BU of 5ama by Molmil
Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with amyloid-beta 1-16
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, ...
著者Masuyer, G, Larmuth, K.M, Douglas, R.G, Sturrock, E.D, Acharya, K.R.
登録日2015-03-10
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Kinetic and Structural Characterisation of Amyloid-Beta Metabolism by Human Angiotensin-1- Converting Enzyme (Ace)
FEBS J., 283, 2016
5M8N
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BU of 5m8n by Molmil
Crystal structure of human tyrosinase related protein 1 in complex with mimosine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W.
登録日2016-10-29
公開日2017-07-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis.
Angew. Chem. Int. Ed. Engl., 56, 2017
5M8T
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BU of 5m8t by Molmil
Crystal structure of human tyrosinase related protein 1 (T391V-R374S-Y362F) in complex with tropolone
分子名称: 2-HYDROXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W.
登録日2016-10-29
公開日2017-07-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis.
Angew. Chem. Int. Ed. Engl., 56, 2017
6E18
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BU of 6e18 by Molmil
Crystal structure of Chlamydomonas reinhardtii HAP2 ectodomain provides structural insights of functional loops in green algae.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Baquero, E, Legrand, P, Rey, F.A.
登録日2018-07-09
公開日2018-11-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Species-Specific Functional Regions of the Green Alga Gamete Fusion Protein HAP2 Revealed by Structural Studies.
Structure, 27, 2019
6J15
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BU of 6j15 by Molmil
Complex structure of GY-5 Fab and PD-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GY-5 heavy chain Fab, ...
著者Chen, D, Tan, S, Zhang, H, Wang, H, Chai, Y, Qi, J, Yan, J, Gao, G.F.
登録日2018-12-27
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy.
Iscience, 14, 2019
6XST
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BU of 6xst by Molmil
Recombinant Beta-2-Glycoprotein I with putative membrane insertion loop
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1, ...
著者Klenotic, P.A, Yu, E.W.Y.
登録日2020-07-16
公開日2021-07-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Beta-2-Glycoprotein I and it's role in APS
To Be Published
7JIK
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BU of 7jik by Molmil
Human recombinant Beta-2-Glycoprotein 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1, ...
著者Klenotic, P.A, Yu, E.W.Y.
登録日2020-07-23
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Beta-2-Glycoprotein I and it's role in APS
To Be Published
7KG4
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BU of 7kg4 by Molmil
Recombinant Beta-2-Glycoprotein I antibody recognition loop mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Klenotic, P.A, Yu, E.W.
登録日2020-10-15
公開日2021-10-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Beta-2-Glycoprotein I and its role in APS
To be published
7LY0
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SARS-CoV-2 S/S2M11/S2M28 Local Refinement
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2M28 Fab Heavy Chain variable region, S2M28 Fab Light Chain variable region, ...
著者McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-03-05
公開日2021-04-14
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2.
Cell, 184, 2021

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