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8PQL
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BU of 8pql by Molmil
K48-linked ubiquitin chain formation with a cullin-RING E3 ligase and Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2-donor UB-acceptor UB-SIL1 peptide
分子名称: 5-azanylpentan-2-one, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
著者Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A.
登録日2023-07-11
公開日2024-02-14
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases.
Nat.Struct.Mol.Biol., 31, 2024
8Q7R
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BU of 8q7r by Molmil
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
分子名称: 5-azanyl-1-oxidanyl-pentan-2-one, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
著者Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A.
登録日2023-08-16
公開日2024-02-21
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Mol.Cell, 84, 2024
8R5H
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BU of 8r5h by Molmil
Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2
分子名称: (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, 5-azanylpentan-2-one, Bromodomain-containing protein 4, ...
著者Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A.
登録日2023-11-16
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Mol.Cell, 84, 2024
8Q5M
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BU of 8q5m by Molmil
N-terminal domain of restriction endonuclease Eco15I in the absence of DNA.
分子名称: Restriction endonuclease (Eco15I)
著者Rafalski, D, Krakowska, K, Bochtler, M.
登録日2023-08-09
公開日2024-07-17
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Structural analysis of the BisI family of modification dependent restriction endonucleases.
To Be Published
3WOC
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BU of 3woc by Molmil
Crystal structure of a prostate-specific WGA16 glycoprotein lectin, form II
分子名称: 1,4-DIETHYLENE DIOXIDE, GLYCEROL, SULFATE ION, ...
著者Garenaux, E, Kanagawa, M, Tsuchiyama, T, Hori, K, Kanazawa, T, Goshima, A, Chiba, M, Yasue, H, Ikeda, A, Yamaguchi, Y, Sato, C, Kitajima, K.
登録日2013-12-26
公開日2014-12-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery, Primary, and Crystal Structures and Capacitation-related Properties of a Prostate-derived Heparin-binding Protein WGA16 from Boar Sperm
J.Biol.Chem., 290, 2015
7WOC
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BU of 7woc by Molmil
Locally refined region of SARS-CoV-2 Spike in complex with IgG 553-60
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, mAb60 VH, ...
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2022-01-21
公開日2022-07-20
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.
J.Virol., 96, 2022
2WOC
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BU of 2woc by Molmil
Crystal Structure of the dinitrogenase reductase-activating glycohydrolase (DRAG) from Rhodospirillum rubrum
分子名称: ADP-RIBOSYL-[DINITROGEN REDUCTASE] GLYCOHYDROLASE, CHLORIDE ION, FORMIC ACID, ...
著者Berthold, C.L, Wang, H, Nordlund, S, Hogbom, M.
登録日2009-07-23
公開日2009-08-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mechanism of Adp-Ribosylation Removal Revealed by the Structure and Ligand Complexes of the Dimanganese Mono-Adp-Ribosylhydrolase Drag.
Proc.Natl.Acad.Sci.USA, 106, 2009
1WOC
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BU of 1woc by Molmil
Crystal structure of PriB
分子名称: Primosomal replication protein n
著者Shioi, S, Ose, T, Maenaka, K, Abe, Y, Kohda, D, Katayama, T, Ueda, T.
登録日2004-08-13
公開日2005-01-25
最終更新日2012-12-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a biologically functional form of PriB from Escherichia coli reveals a potential single-stranded DNA-binding site
Biochem.Biophys.Res.Commun., 326, 2005
5WOC
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BU of 5woc by Molmil
De Novo Design of Covalently Constrained Meso-size Protein Scaffolds with Unique Tertiary Structures
分子名称: (3-methylphenyl)methanol, SER-PRO-GLU-GLU-ARG-ALA-GLN-LEU-CYS-THR-ALA-ALA-GLU-LYS-ALA-ASP-GLU-LEU-GLY
著者Wu, H, Wu, Y, DeGrado, W.F.
登録日2017-08-01
公開日2017-10-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6WOC
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BU of 6woc by Molmil
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 5-diphosphoinositol pentakisphosphate and Mg, presoaked with 5-IP7, Mg and Fluoride, soaking 1min in the absence of Fluoride.
分子名称: (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, ...
著者Zong, G.N, Wang, H.C, Shears, S.B.
登録日2020-04-24
公開日2021-03-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35, 2021
4WOC
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BU of 4woc by Molmil
Proteinase-K Post-Surface Acoustic Waves
分子名称: Proteinase K, SULFATE ION
著者French, J.B.
登録日2014-10-15
公開日2015-02-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
8FBO
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BU of 8fbo by Molmil
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
分子名称: KWOCA_102
著者Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
登録日2022-11-29
公開日2023-03-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FBJ
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BU of 8fbj by Molmil
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
分子名称: KWOCA_60
著者Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
登録日2022-11-29
公開日2023-03-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FBN
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BU of 8fbn by Molmil
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
分子名称: KWOCA_73
著者Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
登録日2022-11-29
公開日2023-03-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FBI
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BU of 8fbi by Molmil
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
分子名称: KWOCA_39
著者Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
登録日2022-11-29
公開日2023-03-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.61 Å)
主引用文献Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FBK
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BU of 8fbk by Molmil
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
分子名称: KWOCA_65
著者Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
登録日2022-11-29
公開日2023-03-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
Proc.Natl.Acad.Sci.USA, 120, 2023
3WOB
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BU of 3wob by Molmil
Crystal structure of a prostate-specific WGA16 glycoprotein lectin, form I
分子名称: hypothetical protein
著者Garenaux, E, Kanagawa, M, Tsuchiyama, T, Hori, K, Kanazawa, T, Goshima, A, Chiba, M, Yasue, H, Ikeda, A, Yamaguchi, Y, Sato, C, Kitajima, K.
登録日2013-12-26
公開日2014-12-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery, Primary, and Crystal Structures and Capacitation-related Properties of a Prostate-derived Heparin-binding Protein WGA16 from Boar Sperm
J.Biol.Chem., 290, 2015
2WOD
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BU of 2wod by Molmil
Crystal Structure of the dinitrogenase reductase-activating glycohydrolase (DRAG) from Rhodospirillum rubrum in complex with ADP- ribsoyllysine
分子名称: ADP-RIBOSYL-[DINITROGEN REDUCTASE] GLYCOHYDROLASE, CHLORIDE ION, GLYCEROL, ...
著者Berthold, C.L, Wang, H, Nordlund, S, Hogbom, M.
登録日2009-07-23
公開日2009-08-11
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Mechanism of Adp-Ribosylation Removal Revealed by the Structure and Ligand Complexes of the Dimanganese Mono-Adp-Ribosylhydrolase Drag.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WOE
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BU of 2woe by Molmil
Crystal Structure of the D97N variant of dinitrogenase reductase- activating glycohydrolase (DRAG) from Rhodospirillum rubrum in complex with ADP-ribose
分子名称: ADP-RIBOSYL-[DINITROGEN REDUCTASE] GLYCOHYDROLASE, GLYCEROL, L(+)-TARTARIC ACID, ...
著者Berthold, C.L, Wang, H, Nordlund, S, Hogbom, M.
登録日2009-07-23
公開日2009-08-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of Adp-Ribosylation Removal Revealed by the Structure and Ligand Complexes of the Dimanganese Mono-Adp-Ribosylhydrolase Drag.
Proc.Natl.Acad.Sci.USA, 106, 2009
4UU8
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BU of 4uu8 by Molmil
Crystal structure of zebrafish Sirtuin 5 in complex with 3,3-dimethyl- succinylated CPS1-peptide
分子名称: 1,2-ETHANEDIOL, 2,2-dimethylbutanedioic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Pannek, M, Gertz, M, Steegborn, C.
登録日2014-07-24
公開日2014-08-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Chemical Probing of the Human Sirtuin 5 Active Site Reveals its Substrate Acyl Specificity and Peptide-Based Inhibitors.
Angew.Chem.Int.Ed.Engl., 53, 2014
4WO9
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BU of 4wo9 by Molmil
Lysozyme Post-Surface Acoustic Waves
分子名称: Lysozyme C, SODIUM ION
著者French, J.B.
登録日2014-10-15
公開日2015-02-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
4WOB
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BU of 4wob by Molmil
Proteinase-K Pre-Surface Acoustic Wave
分子名称: Proteinase K, SULFATE ION
著者French, J.B.
登録日2014-10-15
公開日2015-02-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
4WO6
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BU of 4wo6 by Molmil
Lysozyme Pre-surface acoustic wave
分子名称: Lysozyme C, SODIUM ION
著者French, J.B.
登録日2014-10-15
公開日2015-02-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
4WOA
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BU of 4woa by Molmil
Lysozyme Multiple Crystals After Surface Acoustic Wave Alignment
分子名称: Lysozyme C, SODIUM ION
著者French, J.B.
登録日2014-10-15
公開日2015-02-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
6UCQ
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BU of 6ucq by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome recycling complex
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Zhou, D, Tanzawa, T, Gagnon, M.G, Lin, J.
登録日2019-09-17
公開日2019-12-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis for ribosome recycling by RRF and tRNA.
Nat.Struct.Mol.Biol., 27, 2020

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