Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6WOC

Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 5-diphosphoinositol pentakisphosphate and Mg, presoaked with 5-IP7, Mg and Fluoride, soaking 1min in the absence of Fluoride.

Summary for 6WOC
Entry DOI10.2210/pdb6woc/pdb
DescriptorDiphosphoinositol polyphosphate phosphohydrolase 1, (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordsphosphatase, nudix, catalysis mechanism, substrate specificity, inositol, inositol pyrophosphate, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight20426.76
Authors
Zong, G.N.,Wang, H.C.,Shears, S.B. (deposition date: 2020-04-24, release date: 2021-03-03, Last modification date: 2024-03-06)
Primary citationZong, G.,Jork, N.,Hostachy, S.,Fiedler, D.,Jessen, H.J.,Shears, S.B.,Wang, H.
New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
Faseb J., 35:e21275-e21275, 2021
Cited by
PubMed: 33475202
DOI: 10.1096/fj.202001489R
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.35 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon