1A21
| TISSUE FACTOR (TF) FROM RABBIT | 分子名称: | TISSUE FACTOR | 著者 | Muller, Y.A, De Vos, A.M. | 登録日 | 1998-01-14 | 公開日 | 1998-05-27 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Hinge bending within the cytokine receptor superfamily revealed by the 2.4 A crystal structure of the extracellular domain of rabbit tissue factor. Protein Sci., 7, 1998
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2CEZ
| Phosphorylation of the Cytoplasmic Tail of Tissue Factor and its Role in Modulating Structure and Binding Affinity | 分子名称: | TISSUE FACTOR | 著者 | Sen, M, Agrawal, S, Craft, J.W, Ruf, W, Legge, G.B. | 登録日 | 2006-02-13 | 公開日 | 2007-02-20 | 最終更新日 | 2019-10-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Spectroscopic Characterization of Successive Phosphorylation of the Tissue Factor Cytoplasmic Region. Open Spectrosc J, 3, 2009
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2CEH
| Phosphorylation of the Cytoplasmic Tail of Tissue Factor and its Role in Modulating Structure and Binding Affinity | 分子名称: | TISSUE FACTOR | 著者 | Sen, M, Agrawal, S, Craft, J.W, Ruf, W, Legge, G.B. | 登録日 | 2006-02-06 | 公開日 | 2007-02-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Spectroscopic Characterization of Successive Phosphorylation of the Tissue Factor Cytoplasmic Region. Open Spectrosc.J., 3, 2009
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2CEF
| Phosphorylation of the Cytoplasmic Tail of Tissue Factor and its Role in Modulating Structure and Binding Affinity. | 分子名称: | TISSUE FACTOR | 著者 | Sen, M, Agrawal, S, Craft, J.W, Ruf, W, Legge, G.B. | 登録日 | 2006-02-06 | 公開日 | 2007-02-13 | 最終更新日 | 2019-10-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Spectroscopic Characterization of Successive Phosphorylation of the Tissue Factor Cytoplasmic Region. Open Spectrosc.J., 3, 2009
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2CFJ
| Phosphorylation of the Cytoplasmic Tail of Tissue Factor and its Role in Modulating Structure and Binding Affinity | 分子名称: | TISSUE FACTOR | 著者 | Sen, M, Agrawal, S, Craft, J.W, Ruf, W, Legge, G.B. | 登録日 | 2006-02-21 | 公開日 | 2007-03-20 | 最終更新日 | 2019-10-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Spectroscopic Characterization of Successive Phosphorylation of the Tissue Factor Cytoplasmic Region. Open Spectrosc.J., 3, 2009
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1ADZ
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1IRH
| The Solution Structure of The Third Kunitz Domain of Tissue Factor Pathway Inhibitor | 分子名称: | tissue factor pathway inhibitor | 著者 | Mine, S, Yamazaki, T, Miyata, T, Hara, S, Kato, H. | 登録日 | 2001-10-02 | 公開日 | 2002-02-06 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural mechanism for heparin-binding of the third Kunitz domain of human tissue factor pathway inhibitor. Biochemistry, 41, 2002
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1TFX
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2A2Q
| Complex of Active-site Inhibited Human Coagulation Factor VIIa with Human Soluble Tissue Factor in the Presence of Ca2+, Mg2+, Na+, and Zn2+ | 分子名称: | CALCIUM ION, CHLORIDE ION, Coagulation factor VII, ... | 著者 | Bajaj, S.P, Bajaj, M, Schmidt, A.E, Padmanabhan, K. | 登録日 | 2005-06-22 | 公開日 | 2006-07-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa. J.Biol.Chem., 281, 2006
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1UJ3
| Crystal structure of a humanized Fab fragment of anti-tissue-factor antibody in complex with tissue factor | 分子名称: | IgG Fab heavy chain, IgG Fab light chain, tissue factor | 著者 | Ohto, U, Mizutani, R, Nakamura, M, Adachi, H, Satow, Y. | 登録日 | 2003-07-25 | 公開日 | 2004-07-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of a humanized Fab fragment of anti-tissue-factor antibody in complex with tissue factor. J.Synchrotron Radiat., 11, 2004
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1BOY
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2AER
| Crystal Structure of Benzamidine-Factor VIIa/Soluble Tissue Factor complex. | 分子名称: | BENZAMIDINE, CALCIUM ION, CHLORIDE ION, ... | 著者 | Bajaj, S.P, Schmidt, A.E, Padmanabhan, K, Bajaj, M.S, Liesum, A, Dumas, J, Prevost, D, Schreuder, H. | 登録日 | 2005-07-23 | 公開日 | 2006-07-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | High Resolution Structures of p-Aminobenzamidine- and Benzamidine-VIIa/Soluble Tissue Factor: Unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+ and Zn2+ sites in factor VIIa J.Biol.Chem., 281, 2006
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2EC9
| Crystal structure analysis of human Factor VIIa , Souluble tissue factor complexed with BCX-3607 | 分子名称: | 1,5-anhydro-D-glucitol, 2'-((5-CARBAMIMIDOYLPYRIDIN-2-YLAMINO)METHYL)-4-(ISOBUTYLCARBAMOYL)-4'-VINYLBIPHENYL-2-CARBOXYLIC ACID, CALCIUM ION, ... | 著者 | Raman, K, Yarlagadda, B. | 登録日 | 2007-02-13 | 公開日 | 2008-02-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Probing the S2 site of factor VIIa to generate potent and selective inhibitors: the structure of BCX-3607 in complex with tissue factor-factor VIIa. Acta Crystallogr.,Sect.D, 63, 2007
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1JPS
| Crystal structure of tissue factor in complex with humanized Fab D3h44 | 分子名称: | immunoglobulin Fab D3H44, heavy chain, light chain, ... | 著者 | Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A. | 登録日 | 2001-08-03 | 公開日 | 2002-02-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites. J.Mol.Biol., 313, 2001
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5W06
| HUMAN TISSUE FACTOR IN COMPLEX WITH ANTIBODY M1587 | 分子名称: | GLYCEROL, M1587 FAB HEAVY CHAIN, M1587 FAB LIGHT CHAIN, ... | 著者 | Teplyakov, A, Obmolova, G, Malia, T.J, Gilliland, G.L. | 登録日 | 2017-05-30 | 公開日 | 2017-06-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural insights into humanization of anti-tissue factor antibody 10H10. MAbs, 10, 2018
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4YLQ
| Crystal Structure of a FVIIa-Trypsin Chimera (FT) in Complex with Soluble Tissue Factor | 分子名称: | CALCIUM ION, Coagulation factor VII, N-PROPANOL, ... | 著者 | Sorensen, A.B, Svensson, L.A, Gandhi, P.S. | 登録日 | 2015-03-05 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity. J.Biol.Chem., 291, 2016
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6R2W
| Crystal structure of the super-active FVIIa variant VYT in complex with tissue factor | 分子名称: | CALCIUM ION, Coagulation factor VII, N-acetyl-D-phenylalanyl-N-[(2S,3S)-6-carbamimidamido-1-chloro-2-hydroxyhexan-3-yl]-L-phenylalaninamide, ... | 著者 | Sorensen, A.B, Svensson, L.A, Gandhi, P.S. | 登録日 | 2019-03-19 | 公開日 | 2019-12-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Beating tissue factor at its own game: Design and properties of a soluble tissue factor-independent coagulation factor VIIa. J.Biol.Chem., 295, 2020
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1WQV
| Human Factor Viia-Tissue Factor Complexed with propylsulfonamide-D-Thr-Met-p-aminobenzamidine | 分子名称: | CALCIUM ION, Coagulation factor VII, N-[DIHYDROXY(PROPYL)-LAMBDA~4~-SULFANYL]THREONYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}METHIONINAMIDE, ... | 著者 | Kadono, S, Sakamoto, A, Kikuchi, Y, Oh-eda, M, Yabuta, N, Koga, T, Hattori, K, Shiraishi, T, Haramura, M, Kodama, H. | 登録日 | 2004-10-02 | 公開日 | 2005-10-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of human factor VIIa/tissue factor in complex with peptide mimetic inhibitor Biochem.Biophys.Res.Commun., 324, 2004
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1FAK
| HUMAN TISSUE FACTOR COMPLEXED WITH COAGULATION FACTOR VIIA INHIBITED WITH A BPTI-MUTANT | 分子名称: | CALCIUM ION, PROTEIN (5L15), PROTEIN (BLOOD COAGULATION FACTOR VIIA), ... | 著者 | Zhang, E, St Charles, R, Tulinsky, A. | 登録日 | 1998-12-28 | 公開日 | 1999-12-03 | 最終更新日 | 2023-05-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of extracellular tissue factor complexed with factor VIIa inhibited with a BPTI mutant. J.Mol.Biol., 285, 1999
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2HFT
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4ZMA
| Crystal Structure of a FVIIa-Trypsin Chimera (ST) in Complex with Soluble Tissue Factor | 分子名称: | CACODYLATE ION, CALCIUM ION, Coagulation factor VII, ... | 著者 | Sorensen, A.B, Svensson, L.A, Gandhi, P.S. | 登録日 | 2015-05-02 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity. J.Biol.Chem., 291, 2016
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4Z6A
| Crystal Structure of a FVIIa-Trypsin Chimera (YT) in Complex with Soluble Tissue Factor | 分子名称: | CALCIUM ION, CITRIC ACID, Coagulation factor VII, ... | 著者 | Sorensen, A.B, Svensson, L.A, Gandhi, P.S. | 登録日 | 2015-04-04 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity. J.Biol.Chem., 291, 2016
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1DAN
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1WSS
| Human Factor Viia-Tissue Factor in Complex with peptide-mimetic inhibitor that has two charged groups in P2 and P4 | 分子名称: | CALCIUM ION, Coagulation factor VII, N-[(3-CARBOXYBENZYL)SULFONYL]ISOLEUCYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}-5-IMINOORNITHINAMIDE, ... | 著者 | Kadono, S, Sakamoto, A, Kikuchi, Y, Oh-Eda, M, Yabuta, N, Koga, T, Hattori, K, Shiraishi, T, Haramura, M, Kodama, H, Ono, Y, Esaki, T, Sato, H, Watanabe, Y, Itoh, S, Ohta, M, Kozono, T. | 登録日 | 2004-11-10 | 公開日 | 2005-11-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of human factor VIIa/tissue factor in complex with a peptide-mimetic inhibitor: high selectivity against thrombin by introducing two charged groups in P2 and P4. Acta Crystallogr.,Sect.F, 61, 2005
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1TFH
| EXTRACELLULAR DOMAIN OF HUMAN TISSUE FACTOR | 分子名称: | HUMAN TISSUE FACTOR | 著者 | Huang, M, Syed, R, Stura, E.A, Stone, M.J, Stefanko, R.S, Ruf, W, Edgington, T.S, Wilson, I.A. | 登録日 | 1997-04-10 | 公開日 | 1998-02-25 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex. J.Mol.Biol., 275, 1998
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