2A2Q

Complex of Active-site Inhibited Human Coagulation Factor VIIa with Human Soluble Tissue Factor in the Presence of Ca2+, Mg2+, Na+, and Zn2+

Summary for 2A2Q

Entry DOI	10.2210/pdb2a2q/pdb
Descriptor	Coagulation factor VII, CHLORIDE ION, P-AMINO BENZAMIDINE, ... (12 entities in total)
Functional Keywords	factor viia, soluble tissue factor, mg2+, ca2+, na+, zn2+, hydrolase-blood clotting complex, hydrolase/blood clotting
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	69947.32
Authors	Bajaj, S.P.,Bajaj, M.,Schmidt, A.E.,Padmanabhan, K. (deposition date: 2005-06-22, release date: 2006-07-04, Last modification date: 2023-11-15)
Primary citation	Bajaj, S.P.,Schmidt, A.E.,Agah, S.,Bajaj, M.S.,Padmanabhan, K. High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa. J.Biol.Chem., 281:24873-24888, 2006 Cited by PubMed: 16757484 DOI: 10.1074/jbc.M509971200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation