2EC9
Crystal structure analysis of human Factor VIIa , Souluble tissue factor complexed with BCX-3607
Summary for 2EC9
Entry DOI | 10.2210/pdb2ec9/pdb |
Related | 1DAN |
Descriptor | Coagulation factor VII, Tissue factor, 1,5-anhydro-D-glucitol, ... (9 entities in total) |
Functional Keywords | protein-cofactor complex, fviia and souluble tissue factor, inhibitor, blood clotting |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 68084.69 |
Authors | Raman, K.,Yarlagadda, B. (deposition date: 2007-02-13, release date: 2008-02-19, Last modification date: 2023-11-15) |
Primary citation | Krishnan, R.,Kotian, P.L.,Chand, P.,Bantia, S.,Rowland, S.,Babu, Y.S. Probing the S2 site of factor VIIa to generate potent and selective inhibitors: the structure of BCX-3607 in complex with tissue factor-factor VIIa. Acta Crystallogr.,Sect.D, 63:689-697, 2007 Cited by PubMed: 17505107DOI: 10.1107/S0907444907014187 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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