2EC9
Crystal structure analysis of human Factor VIIa , Souluble tissue factor complexed with BCX-3607
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Coagulation factor VII | polymer | 142 | 16359.8 | 1 | UniProt (P08709) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) | Homo sapiens (human) | Serum prothrombin conversion accelerator, SPCA, Proconvertin, Eptacog alfa |
| 2 | B (H) | Coagulation factor VII | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) | Homo sapiens (human) | Serum prothrombin conversion accelerator, SPCA, Proconvertin, Eptacog alfa |
| 3 | C (T) | Tissue factor | polymer | 75 | 8715.8 | 1 | UniProt (P13726) Pfam (PF01108) | Homo sapiens (human) | TF, Coagulation factor III, Thromboplastin, CD142 antigen |
| 4 | D (U) | Tissue factor | polymer | 120 | 13745.3 | 1 | UniProt (P13726) Pfam (PF09294) | Homo sapiens (human) | TF, Coagulation factor III, Thromboplastin, CD142 antigen |
| 5 | E (L) | 1,5-anhydro-D-glucitol | non-polymer | 164.2 | 1 | Chemie (ASO) | |||
| 6 | F (L) | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 7 | G, H, I, J, K... (L, H) | CALCIUM ION | non-polymer | 40.1 | 9 | Chemie (CA) | |||
| 8 | P (H) | 2'-((5-CARBAMIMIDOYLPYRIDIN-2-YLAMINO)METHYL)-4-(ISOBUTYLCARBAMOYL)-4'-VINYLBIPHENYL-2-CARBOXYLIC ACID | non-polymer | 471.6 | 1 | Chemie (24X) | |||
| 9 | Q, R, S, T (L, H, T, U) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 66924.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1160.6 | |
| All* | Total formula weight | 68084.7 |
