2EC9
Crystal structure analysis of human Factor VIIa , Souluble tissue factor complexed with BCX-3607
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Coagulation factor VII | polymer | 142 | 16359.8 | 1 | UniProt (P08709) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) | Homo sapiens (human) | Serum prothrombin conversion accelerator, SPCA, Proconvertin, Eptacog alfa |
| 2 | B (H) | Coagulation factor VII | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) | Homo sapiens (human) | Serum prothrombin conversion accelerator, SPCA, Proconvertin, Eptacog alfa |
| 3 | C (T) | Tissue factor | polymer | 75 | 8715.8 | 1 | UniProt (P13726) Pfam (PF01108) | Homo sapiens (human) | TF, Coagulation factor III, Thromboplastin, CD142 antigen |
| 4 | D (U) | Tissue factor | polymer | 120 | 13745.3 | 1 | UniProt (P13726) Pfam (PF09294) | Homo sapiens (human) | TF, Coagulation factor III, Thromboplastin, CD142 antigen |
| 5 | E (L) | 1,5-anhydro-D-glucitol | non-polymer | 164.2 | 1 | Chemie (ASO) PubChem (22858201) PubChem (22858202) PubChem (22882785) PubChem (29972132) PubChem (38989255) PubChem (40486040) PubChem (40486041) PubChem (64960) PubChem (45038171) PubChem (46780406) PubChem (53821891) PubChem (53821892) PubChem (53821893) PubChem (54083961) PubChem (54083962) PubChem (57076893) PubChem (57101566) PubChem (57102329) PubChem (57128190) PubChem (57134792) PubChem (57161875) PubChem (57256623) PubChem (58076495) PubChem (59922885) PubChem (60003539) PubChem (60022964) PubChem (67891773) PubChem (68022668) PubChem (68022670) PubChem (68225447) PubChem (69033058) PubChem (445184) PubChem (445234) PubChem (70331649) PubChem (446996) PubChem (89098875) PubChem (89143019) PubChem (89574841) PubChem (89820758) PubChem (89969175) PubChem (91126818) PubChem (91317021) PubChem (91528084) PubChem (6102335) PubChem (117972890) PubChem (11094970) PubChem (11829766) PubChem (12905135) PubChem (15558203) PubChem (15558204) PubChem (129134545) PubChem (137473745) PubChem (141789579) PubChem (148524636) PubChem (159630737) PubChem (173276173) PubChem (173895539) PubChem (174418124) PubChem (174605793) PubChem (175080585) PubChem (176029745) PubChem (219984) | |||
| 6 | F (L) | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 7 | G, H, I, J, K... (L, H) | CALCIUM ION | non-polymer | 40.1 | 9 | Chemie (CA) PubChem (271) | |||
| 8 | P (H) | 2'-((5-CARBAMIMIDOYLPYRIDIN-2-YLAMINO)METHYL)-4-(ISOBUTYLCARBAMOYL)-4'-VINYLBIPHENYL-2-CARBOXYLIC ACID | non-polymer | 471.6 | 1 | Chemie (24X) PubChem (9912630) | |||
| 9 | Q, R, S, T (L, H, T, U) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 66924.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1160.6 | |
| All* | Total formula weight | 68084.7 |
