2AER

Crystal Structure of Benzamidine-Factor VIIa/Soluble Tissue Factor complex.

Summary for 2AER

Entry DOI	10.2210/pdb2aer/pdb
Descriptor	Coagulation factor VII, CHLORIDE ION, BENZAMIDINE, ... (12 entities in total)
Functional Keywords	serine protease, calcium, magnesium, zinc, sodium, factor viia, tissue factor, benzamidine, blood coagulation, clotting, blood, coagulation, clotting factor, coagulation factor, blood clotting
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	68875.07
Authors	Bajaj, S.P.,Schmidt, A.E.,Padmanabhan, K.,Bajaj, M.S.,Liesum, A.,Dumas, J.,Prevost, D.,Schreuder, H. (deposition date: 2005-07-23, release date: 2006-07-04, Last modification date: 2023-11-15)
Primary citation	Bajaj, S.P.,Schmidt, A.E.,Agah, S.,Bajaj, M.S.,Padmanabhan, K. High Resolution Structures of p-Aminobenzamidine- and Benzamidine-VIIa/Soluble Tissue Factor: Unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+ and Zn2+ sites in factor VIIa J.Biol.Chem., 281:24873-24888, 2006 Cited by PubMed: 16757484 DOI: 10.1074/jbc.M509971200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.87 Å)

Structure validation