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2NYT
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The APOBEC2 Crystal Structure and Functional Implications for AID
分子名称: Probable C->U-editing enzyme APOBEC-2, ZINC ION
著者Prochnow, C, Bransteitter, R, Klein, M, Goodman, M, Chen, X.
登録日2006-11-21
公開日2007-01-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The APOBEC-2 crystal structure and functional implications for the deaminase AID.
Nature, 445, 2007
2JYW
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BU of 2jyw by Molmil
Solution structure of C-terminal domain of APOBEC3G
分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
著者Chen, K, Harjes, E, Gross, P.J, Fahmy, A, Lu, Y, Shindo, K, Harris, R.S, Matsuo, H.
登録日2007-12-20
公開日2008-02-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G.
Nature, 452, 2008
3E1U
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BU of 3e1u by Molmil
The Crystal Structure of the Anti-Viral APOBEC3G Catalytic Domain
分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
著者Holden, L, Prochnow, C, Chang, Y.P, Bransteitter, R, Chelico, L, Sen, U, Stevens, R.C, Goodman, R.F, Chen, X.S.
登録日2008-08-04
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Nature, 456, 2008
2KBO
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BU of 2kbo by Molmil
Structure, interaction, and real-time monitoring of the enzymatic reaction of wild type APOBEC3G
分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
著者Furukawa, A, Nagata, T, Matsugami, A, Habu, Y, Sugiyama, R, Hayashi, F, Kobayashi, N, Yokoyama, S, Takaku, H, Katahira, M.
登録日2008-12-04
公開日2009-02-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G
Embo J., 28, 2009
2KEM
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BU of 2kem by Molmil
Extended structure of citidine deaminase domain of APOBEC3G
分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
著者Harjes, E, Gross, P.J, Chen, K, Lu, Y, Shindo, K, Nowarski, R, Gross, J.D, Kotler, M, Harris, R.S, Matsuo, H.
登録日2009-01-30
公開日2009-06-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model
J.Mol.Biol., 389, 2009
3IQS
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BU of 3iqs by Molmil
Crystal structure of the anti-viral APOBEC3G catalytic domain
分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
著者Holden, L.G, Prochnow, C, Chang, Y.P, Bransteitter, R, Chelico, L, Sen, U, Stevens, R.C, Goodman, R.F, Chen, X.S.
登録日2009-08-20
公開日2009-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Nature, 456, 2008
3IR2
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BU of 3ir2 by Molmil
Crystal structure of the APOBEC3G catalytic domain
分子名称: CHLORIDE ION, DNA dC->dU-editing enzyme APOBEC-3G, MAGNESIUM ION, ...
著者Shandilya, S.M.D, Schiffer, C.A.
登録日2009-08-21
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces.
Structure, 18, 2010
3V4K
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BU of 3v4k by Molmil
First-In-Class Small Molecule Inhibitors of the Single-strand DNA Cytosine Deaminase APOBEC3G
分子名称: CHLORIDE ION, DNA dC->dU-editing enzyme APOBEC-3G, MAGNESIUM ION, ...
著者Shandilya, S.M.D, Ali, A, Schiffer, C.A.
登録日2011-12-15
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G.
Acs Chem.Biol., 7, 2012
3V4J
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BU of 3v4j by Molmil
First-In-Class Small Molecule Inhibitors of the Single-strand DNA Cytosine Deaminase APOBEC3G
分子名称: 4-[methyl(nitroso)amino]benzene-1,2-diol, DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
著者Shandilya, S.M.D, Ali, A, Schiffer, C.A.
登録日2011-12-15
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G.
Acs Chem.Biol., 7, 2012
2M65
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BU of 2m65 by Molmil
NMR structure of human restriction factor APOBEC3A
分子名称: Probable DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION
著者Byeon, I.L, Byeon, C, Ahn, J, Gronenborn, A.M.
登録日2013-03-21
公開日2013-05-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity.
Nat Commun, 4, 2013
4ROV
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BU of 4rov by Molmil
The crystal structure of novel APOBEC3G CD2 head-to-tail dimer suggests the binding mode of full-length APOBEC3G to HIV-1 ssDNA
分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
著者Lu, X, Zhang, T, Xu, Z, Liu, S, Zhao, B, Lan, W, Wang, C, Ding, J, Cao, C.
登録日2014-10-29
公開日2014-12-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
J.Biol.Chem., 290, 2015
4ROW
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BU of 4row by Molmil
The crystal structure of novel APOBEC3G CD2 head-to-tail dimer suggests the binding mode of full-length APOBEC3G to HIV-1 ssDNA
分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
著者Lu, X, Zhang, T, Xu, Z, Liu, S, Zhao, B, Lan, W, Wang, C, Ding, J, Cao, C.
登録日2014-10-29
公開日2014-12-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
J.Biol.Chem., 290, 2015
4XXO
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BU of 4xxo by Molmil
Crystal Structure of Human APOBEC3A
分子名称: CHLORIDE ION, DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION
著者Bohn, M.F, Shandilya, S.M.D, Schiffer, C.A.
登録日2015-01-30
公開日2015-04-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.843 Å)
主引用文献The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.
Structure, 23, 2015
5CQK
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BU of 5cqk by Molmil
Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B
分子名称: DNA dC->dU-editing enzyme APOBEC-3B, GLYCEROL, SODIUM ION, ...
著者Shi, K, Kurahashi, K, Aihara, H.
登録日2015-07-21
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
J.Biol.Chem., 290, 2015
5CQI
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BU of 5cqi by Molmil
Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B
分子名称: DNA dC-dU-editing enzyme APOBEC-3B, GLYCEROL, ZINC ION
著者Shi, K, Kurahashi, K, Aihara, H.
登録日2015-07-21
公開日2015-10-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
J.Biol.Chem., 290, 2015
5CQH
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Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, CHLORIDE ION, ...
著者Shi, K, Kurahashi, K, Aihara, H.
登録日2015-07-21
公開日2015-10-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
J.Biol.Chem., 290, 2015
5CQD
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BU of 5cqd by Molmil
Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B
分子名称: DNA dC->dU-editing enzyme APOBEC-3B, GLYCEROL, ZINC ION
著者Shi, K, Kurahashi, K, Aihara, H.
登録日2015-07-21
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
J.Biol.Chem., 290, 2015
2NBQ
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BU of 2nbq by Molmil
NMR Structure of the C-Terminal Domain of human APOBEC3B
分子名称: DNA dC->dU-editing enzyme APOBEC-3B, ZINC ION
著者Byeon, I.L, Byeon, C, Gronenborn, A.M.
登録日2016-03-09
公開日2016-06-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Nuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity.
Biochemistry, 55, 2016
5SWW
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BU of 5sww by Molmil
Crystal Structure of Human APOBEC3A complexed with ssDNA
分子名称: DNA 15-Mer, DNA dC->dU-editing enzyme APOBEC-3A, GLYCEROL, ...
著者Shi, K, Banerjee, S, Kurahashi, K, Aihara, H.
登録日2016-08-09
公開日2016-12-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.151 Å)
主引用文献Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.
Nat. Struct. Mol. Biol., 24, 2017
5TD5
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BU of 5td5 by Molmil
Crystal Structure of Human APOBEC3B variant complexed with ssDNA
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(P*TP*TP*CP*AP*T)-3'), ...
著者Shi, K, Banerjee, S, Kurahashi, K, Aihara, H.
登録日2016-09-16
公開日2016-12-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.718 Å)
主引用文献Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.
Nat. Struct. Mol. Biol., 24, 2017
5KEG
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BU of 5keg by Molmil
Crystal structure of APOBEC3A in complex with a single-stranded DNA
分子名称: CALCIUM ION, CHLORIDE ION, DNA (5'-D(*TP*TP*CP*TP*T)-3'), ...
著者Kouno, T, Hilbert, B.J, Silvas, T, Royer, W.E, Matsuo, H, Schiffer, C.A.
登録日2016-06-09
公開日2017-05-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.
Nat Commun, 8, 2017
5SXG
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BU of 5sxg by Molmil
Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B
分子名称: 1,3-PROPANDIOL, DNA dC->dU-editing enzyme APOBEC-3B, IMIDAZOLE, ...
著者Shi, K, Kurahashi, K, Aihara, H.
登録日2016-08-09
公開日2017-12-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.
Sci Rep, 7, 2017
5SXH
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BU of 5sxh by Molmil
Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B
分子名称: 1,2-ETHANEDIOL, DNA dC->dU-editing enzyme APOBEC-3B, ZINC ION
著者Shi, K, Kurahashi, K, Aihara, H.
登録日2016-08-09
公開日2017-12-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.
Sci Rep, 7, 2017
6BWY
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DNA substrate selection by APOBEC3G
分子名称: DNA (30-MER), PHOSPHATE ION, Protection of telomeres protein 1, ...
著者Ziegler, S.J, Buzovetsky, O.
登録日2017-12-15
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.
PLoS ONE, 13, 2018
6BUX
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CRYSTAL STRUCTURE OF APOBEC3G CATALYTIC DOMAIN COMPLEX WITH SUBSTRATE SSDNA
分子名称: Apolipoprotein B mRNA editing enzyme catalytic subunit 3G catalytic domain, DNA (5'-D(*AP*AP*TP*CP*CP*CP*AP*AP*A)-3'), GLYCEROL, ...
著者Maiti, A, Matsuo, H.
登録日2017-12-11
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.856 Å)
主引用文献Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA.
Nat Commun, 9, 2018

 

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