Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B

Summary for 5CQD

Related5CQH 5CQI 5CQK
DescriptorDNA dC->dU-editing enzyme APOBEC-3B, ZINC ION, GLYCEROL, ... (4 entities in total)
Functional Keywordsapobec, deaminase, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationNucleus  Q9UH17
Total number of polymer chains2
Total molecular weight44549.21
Shi, K.,Kurahashi, K.,Aihara, H. (deposition date: 2015-07-21, release date: 2015-10-07, Last modification date: 2017-09-27)
Primary citation
Shi, K.,Carpenter, M.A.,Kurahashi, K.,Harris, R.S.,Aihara, H.
Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
J.Biol.Chem., 290:28120-28130, 2015
PubMed: 26416889 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M115.679951
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.228202.7%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution