Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B

Summary for 5CQD

Related5CQH 5CQI 5CQK
DescriptorDNA dC->dU-editing enzyme APOBEC-3B, ZINC ION, GLYCEROL, ... (4 entities in total)
Functional Keywordsapobec, deaminase, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight44549.21
Shi, K.,Kurahashi, K.,Aihara, H. (deposition date: 2015-07-21, release date: 2015-10-07, Last modification date: 2019-12-11)
Primary citation
Shi, K.,Carpenter, M.A.,Kurahashi, K.,Harris, R.S.,Aihara, H.
Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.
J.Biol.Chem., 290:28120-28130, 2015
PubMed: 26416889 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M115.679951
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22820 2.7% 3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21