5TD5
Crystal Structure of Human APOBEC3B variant complexed with ssDNA
Summary for 5TD5
Entry DOI | 10.2210/pdb5td5/pdb |
Descriptor | DNA dC->dU-editing enzyme APOBEC-3B, DNA (5'-D(P*TP*TP*CP*AP*T)-3'), ZINC ION, ... (7 entities in total) |
Functional Keywords | deaminase, dna substrate complex, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q9UH17 |
Total number of polymer chains | 2 |
Total formula weight | 26122.60 |
Authors | Shi, K.,Banerjee, S.,Kurahashi, K.,Aihara, H. (deposition date: 2016-09-16, release date: 2016-12-28, Last modification date: 2024-03-06) |
Primary citation | Shi, K.,Carpenter, M.A.,Banerjee, S.,Shaban, N.M.,Kurahashi, K.,Salamango, D.J.,McCann, J.L.,Starrett, G.J.,Duffy, J.V.,Demir, O.,Amaro, R.E.,Harki, D.A.,Harris, R.S.,Aihara, H. Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B. Nat. Struct. Mol. Biol., 24:131-139, 2017 Cited by PubMed: 27991903DOI: 10.1038/nsmb.3344 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.718 Å) |
Structure validation
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