5TD5

Crystal Structure of Human APOBEC3B variant complexed with ssDNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 401

Chain	Residue
A	HIS253
A	CYS284
A	CYS289
A	CL417

---

site_id	AC2
Number of Residues	1
Details	binding site for residue IOD A 403

Chain	Residue
A	HOH569

---

site_id	AC3
Number of Residues	2
Details	binding site for residue IOD A 404

Chain	Residue
A	ASP194
C	DA1

---

site_id	AC4
Number of Residues	3
Details	binding site for residue IOD A 405

Chain	Residue
C	DT-2
A	ARG211
A	HIS212

---

site_id	AC5
Number of Residues	4
Details	binding site for residue IOD A 407

Chain	Residue
A	ARG211
A	HIS212
C	DT-2
C	DA1

---

site_id	AC6
Number of Residues	1
Details	binding site for residue EDO A 410

Chain	Residue
A	HOH527

---

site_id	AC7
Number of Residues	8
Details	binding site for residue EDO A 411

Chain	Residue
A	GLY251
A	ARG252
A	HIS253
A	LEU256
A	TRP287
A	CYS289
A	EDO412
A	HOH502

---

site_id	AC8
Number of Residues	6
Details	binding site for residue EDO A 412

Chain	Residue
A	HIS253
A	TRP287
A	TYR313
A	EDO411
C	DC0
C	DA1

---

site_id	AC9
Number of Residues	3
Details	binding site for residue EDO A 413

Chain	Residue
A	ARG374
A	LEU377
A	HOH508

---

site_id	AD1
Number of Residues	6
Details	binding site for residue EDO A 414

Chain	Residue
A	ARG190
A	TYR191
A	TYR218
A	GLY236
A	PHE237
A	HOH550

---

site_id	AD2
Number of Residues	3
Details	binding site for residue EDO A 415

Chain	Residue
A	GLY205
A	TRP281
C	DT-1

---

site_id	AD3
Number of Residues	1
Details	binding site for residue CL A 416

Chain	Residue
A	HIS365

---

site_id	AD4
Number of Residues	6
Details	binding site for residue CL A 417

Chain	Residue
A	HIS253
A	PRO283
A	CYS284
A	CYS289
A	ZN401
C	DC0

---

site_id	AD5
Number of Residues	2
Details	binding site for residue IOD C 101

Chain	Residue
A	ASP194
C	DA1

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---