5SXG

Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B

Summary for 5SXG

• Entry DOI: 10.2210/pdb5sxg/pdb
• Descriptor: DNA dC->dU-editing enzyme APOBEC-3B, ZINC ION, 1,3-PROPANDIOL, ... (5 entities in total)
• Functional Keywords: apobec, deaminase, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 44299.84

Authors

Shi, K.,Kurahashi, K.,Aihara, H. (deposition date: 2016-08-09, release date: 2017-12-27, Last modification date: 2023-10-04)

• Primary citation: Shi, K.,Demir, O.,Carpenter, M.A.,Wagner, J.,Kurahashi, K.,Harris, R.S.,Amaro, R.E.,Aihara, H.; Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.; Sci Rep, 7:17415-17415, 2017; PubMed: 29234087; DOI: 10.1038/s41598-017-17694-3

Experimental method

X-RAY DIFFRACTION (1.93 Å)