2QP2
 
 | | Structure of a MACPF/perforin-like protein | | 分子名称: | CALCIUM ION, Unknown protein | | 著者 | Rosado, C.J, Buckle, A.M, Law, R.H.P, Butcher, R.E, Kan, W.T, Bird, C.H, Ung, K, Browne, K.A, Baran, K, Bashtannyk-Puhalovich, T.A, Faux, N.G, Wong, W, Porter, C.J, Pike, R.N, Ellisdon, A.M, Pearce, M.C, Bottomley, S.P, Emsley, J, Smith, A.I, Rossjohn, J, Hartland, E.L, Voskoboinik, I, Trapani, J.A, Bird, P.I, Dunstone, M.A, Whisstock, J.C. | | 登録日 | 2007-07-22 | | 公開日 | 2007-09-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A common fold mediates vertebrate defense and bacterial attack
Science, 317, 2007
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2QQH
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2RD7
 | | Human Complement Membrane Attack Proteins Share a Common Fold with Bacterial Cytolysins | | 分子名称: | CHLORIDE ION, Complement component C8 alpha chain, Complement component C8 gamma chain | | 著者 | Slade, D.J, Lovelace, L.L, Chruszcz, M, Minor, W, Lebioda, L, Sodetz, J.M. | | 登録日 | 2007-09-21 | | 公開日 | 2008-05-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J. Biol. Chem., 286, 2011
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3NSJ
 | | The X-ray crystal structure of lymphocyte perforin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Law, R.H, Whisstock, J.C, Caradoc-Davies, T.T. | | 登録日 | 2010-07-01 | | 公開日 | 2010-11-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | The structural basis for membrane binding and pore formation by lymphocyte perforin.
Nature, 468, 2010
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3OJY
 | | Crystal Structure of Human Complement Component C8 | | 分子名称: | CALCIUM ION, Complement component C8 alpha chain, Complement component C8 beta chain, ... | | 著者 | Lovelace, L.L, Cooper, C.L, Sodetz, J.M, Lebioda, L. | | 登録日 | 2010-08-23 | | 公開日 | 2011-04-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J.Biol.Chem., 286, 2011
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3T5O
 | | Crystal Structure of human Complement Component C6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, Complement component C6, ... | | 著者 | Aleshin, A.E, Stec, B, Bankston, L.A, DiScipio, R.G, Liddington, R.C. | | 登録日 | 2011-07-27 | | 公開日 | 2012-02-01 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.869 Å) | | 主引用文献 | Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC).
J.Biol.Chem., 287, 2012
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4A5W
 | | Crystal structure of C5b6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C5, ... | | 著者 | Hadders, M.A, Bubeck, D, Forneris, F, Pangburn, M, Llorca, O, Lea, S.M, Gros, P. | | 登録日 | 2011-10-28 | | 公開日 | 2012-03-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
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4E0S
 | | Crystal Structure of C5b-6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C5, ... | | 著者 | Aleshin, A.E, Stec, B, DiScipio, R, Liddington, R.C. | | 登録日 | 2012-03-05 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (4.21 Å) | | 主引用文献 | Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex.
J.Biol.Chem., 287, 2012
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5FMW
 | | The poly-C9 component of the Complement Membrane Attack Complex | | 分子名称: | POLYC9 | | 著者 | Dudkina, N.V, Spicer, B.A, Reboul, C.F, Conroy, P.J, Lukoyanova, N, Elmlund, H, Law, R.H.P, Ekkel, S.M, Kondos, S.C, Goode, R.J.A, Ramm, G, Whisstock, J.C, Saibil, H.R, Dunstone, M.A. | | 登録日 | 2015-11-10 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Structure of the Poly-C9 Component of the Complement Membrane Attack Complex
Nat.Commun., 7, 2016
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5J67
 | | Structure of Astrotactin-2, a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Astrotactin-2, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | | 著者 | Ni, T, Harlos, K, Gilbert, R.J.C. | | 登録日 | 2016-04-04 | | 公開日 | 2016-05-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | | 主引用文献 | Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.
Open Biology, 6, 2016
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5J68
 | | Structure of Astrotactin-2, a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Astrotactin-2, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | | 著者 | Ni, T, Harlos, K, Gilbert, R.J.C. | | 登録日 | 2016-04-04 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (5.221 Å) | | 主引用文献 | Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.
Open Biology, 6, 2016
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5J69
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5OUP
 | | Structure of TgPLP1 MACPF domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Perforin-like protein 1 | | 著者 | Ni, T, Gilbert, R.J.C. | | 登録日 | 2017-08-24 | | 公開日 | 2018-04-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Structures of monomeric and oligomeric forms of theToxoplasma gondiiperforin-like protein 1.
Sci Adv, 4, 2018
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5OUQ
 | | Structure of TgPLP1 MACPF domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Perforin-like protein 1 | | 著者 | Ni, T, Gilbert, R.J.C. | | 登録日 | 2017-08-24 | | 公開日 | 2018-04-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (5.11 Å) | | 主引用文献 | Structures of monomeric and oligomeric forms of theToxoplasma gondiiperforin-like protein 1.
Sci Adv, 4, 2018
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5OWN
 | | Structure of TgPLP1 MACPF domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Perforin-like protein 1 | | 著者 | Ni, T, Gilbert, R.J.C. | | 登録日 | 2017-09-01 | | 公開日 | 2018-04-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Structures of monomeric and oligomeric forms of theToxoplasma gondiiperforin-like protein 1.
Sci Adv, 4, 2018
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6CXO
 | | Complement component-9 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement component C9, ... | | 著者 | Law, R.H.P, Spicer, B.A, Caradoc-Davies, T.T. | | 登録日 | 2018-04-03 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
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6DLW
 | | Complement component polyC9 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement component C9, beta-D-mannopyranose | | 著者 | Dunstone, M.A, Spicer, B.A, Law, R.H.P. | | 登録日 | 2018-06-03 | | 公開日 | 2018-09-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
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6FBM
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6H03
 | | OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ... | | 著者 | Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D. | | 登録日 | 2018-07-06 | | 公開日 | 2018-12-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
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6H04
 | | Closed conformation of the Membrane Attack Complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ... | | 著者 | Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D. | | 登録日 | 2018-07-06 | | 公開日 | 2018-12-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
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6SB3
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6SB5
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6U23
 | | EM structure of MPEG-1(w.t.) soluble pre-pore | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein | | 著者 | Pang, S.S, Bayly-Jones, C. | | 登録日 | 2019-08-19 | | 公開日 | 2019-09-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
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6U2J
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6U2K
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