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6A70
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Structure of the human PKD1/PKD2 complex
分子名称: Polycystin-1, Polycystin-2
著者Su, Q, Hu, F, Ge, X, Lei, J, Yu, S, Wang, T, Zhou, Q, Mei, C, Shi, Y.
登録日2018-06-29
公開日2018-08-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of the human PKD1-PKD2 complex.
Science, 361, 2018
2FNQ
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BU of 2fnq by Molmil
Insights from the X-ray crystal structure of coral 8R-lipoxygenase: calcium activation via A C2-like domain and a structural basis of product chirality
分子名称: Allene oxide synthase-lipoxygenase protein, CALCIUM ION, FE (II) ION
著者Oldham, M.L, Brash, A.R, Newcomer, M.E.
登録日2006-01-11
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Insights from the X-ray crystal structure of coral 8R-lipoxygenase: calcium activation via a C2-like domain and a structural basis of product chirality.
J.Biol.Chem., 280, 2005
1W52
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Crystal structure of a proteolyzed form of pancreatic lipase related protein 2 from horse
分子名称: CALCIUM ION, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, PANCREATIC LIPASE RELATED PROTEIN 2
著者Mancheno, J.M, Jayne, S, Kerfelec, B, Chapus, C, Crenon, I, Hermoso, J.A.
登録日2004-08-04
公開日2006-07-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Crystalization of a Proteolyzed Form of the Horse Pancreatic Lipase-Related Protein 2: Structural Basis for the Specific Detergent Requirement.
Acta Crystallogr.,Sect.D, 60, 2004
6E7K
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Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma triglyceride hydrolysis
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Birrane, G, Meiyappan, M.
登録日2018-07-26
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
8I6Y
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Crystal structure of Arabidopsis thaliana LOX1
分子名称: FE (III) ION, Linoleate 9S-lipoxygenase 1
著者Liu, X, Liu, L.
登録日2023-01-30
公開日2024-02-07
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献UV-B light signal mediates stomatal closure by activating the 9-lipoxygenase pathway
To Be Published
7LAF
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15-lipoxygenase-2 loop mutant bound to imidazole-based inhibitor
分子名称: 3-{[(4-methylphenyl)methyl]sulfanyl}-1-phenyl-1H-1,2,4-triazole, MANGANESE (II) ION, Polyunsaturated fatty acid lipoxygenase ALOX15B
著者Newcomer, M.E, Gilbert, N.C, Neau, D.B.
登録日2021-01-06
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2.
Bioorg.Med.Chem., 46, 2021
4NRE
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The structure of human 15-lipoxygenase-2 with a substrate mimic
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Arachidonate 15-lipoxygenase B, CALCIUM ION, ...
著者Kobe, M.J, Neau, D.B, Mitchell, C.E, Bartlett, S.G, Newcomer, M.E.
登録日2013-11-26
公開日2014-02-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献The structure of human 15-lipoxygenase-2 with a substrate mimic.
J.Biol.Chem., 289, 2014
3PZW
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Soybean lipoxygenase-1 - re-refinement
分子名称: 1,2-ETHANEDIOL, ACETATE ION, FE (II) ION, ...
著者Chruszcz, M, Minor, W.
登録日2010-12-14
公開日2011-01-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Determination of protein structures - a series of fortunate events.
Biophys.J., 95, 2008
3O8Y
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Stable-5-Lipoxygenase
分子名称: Arachidonate 5-lipoxygenase, FE (II) ION
著者Newcomer, M.E, Gilbert, N.C, Bartlett, S.G, Waight, M.T, Neau, D.B, Boeglin, W.E, Brash, A.R.
登録日2010-08-03
公開日2011-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.389 Å)
主引用文献The structure of human 5-lipoxygenase.
Science, 331, 2011
6OAZ
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Apo Structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in HEK293-F cells
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Arora, R, Horton, P.A, Benson, T.E, Romanowski, M.J.
登録日2019-03-19
公開日2019-05-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Structure of lipoprotein lipase in complex with GPIHBP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
8ERL
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CryoEM Structure of Lipoprotein Lipase Dimer
分子名称: Lipoprotein lipase
著者Gunn, K.H, Neher, S.B.
登録日2022-10-12
公開日2023-05-03
最終更新日2023-05-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure of dimeric lipoprotein lipase reveals a pore adjacent to the active site.
Nat Commun, 14, 2023
6U7M
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Cryo-EM Structure of Helical Lipoprotein Lipase
分子名称: Lipoprotein lipase
著者Gunn, K.H, Wang, F, Egelman, E.H, Neher, S.B.
登録日2019-09-03
公開日2020-04-08
最終更新日2020-05-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage.
Proc.Natl.Acad.Sci.USA, 117, 2020
5EEO
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soybean lipoxygenase(L1)-T756R
分子名称: FE (II) ION, Seed linoleate 13S-lipoxygenase-1
著者Mikami, B, Nagaya, T, Hioki, Y.
登録日2015-10-23
公開日2015-11-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structural basis for specificity in lipoxygenase catalysis
To Be Published
4QWT
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Anaerobic crystal structure of delta413-417:GS LOX in complex with arachidonate
分子名称: ACETATE ION, ARACHIDONIC ACID, Allene oxide synthase-lipoxygenase protein, ...
著者Neau, D.B, Newcomer, M.E.
登録日2014-07-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Crystal Structure of a Lipoxygenase in Complex with Substrate: THE ARACHIDONIC ACID-BINDING SITE OF 8R-LIPOXYGENASE.
J.Biol.Chem., 289, 2014
5T5V
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LIPOXYGENASE-1 (SOYBEAN) AT 293K
分子名称: FE (III) ION, Seed linoleate 13S-lipoxygenase-1
著者Poss, E.M, Fraser, J.S.
登録日2016-08-31
公開日2017-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hydrogen-Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling.
ACS Cent Sci, 3, 2017
3BND
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Lipoxygenase-1 (Soybean), I553V Mutant
分子名称: FE (III) ION, Seed lipoxygenase-1
著者Tomchick, D.R.
登録日2007-12-14
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
4WHA
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Lipoxygenase-1 (soybean) L546A/L754A mutant
分子名称: 1,2-ETHANEDIOL, ACETATE ION, FE (III) ION, ...
著者Scouras, A.D, Carr, C.A.M, Hu, S, Klinman, J.P.
登録日2014-09-21
公開日2014-11-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Extremely elevated room-temperature kinetic isotope effects quantify the critical role of barrier width in enzymatic C-H activation.
J.Am.Chem.Soc., 136, 2014
2IUJ
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Crystal Structure of Soybean Lipoxygenase-B
分子名称: FE (III) ION, LIPOXYGENASE L-5
著者Youn, B, Sellhorn, G.E, Mirchel, R.J, Gaffney, B.J, Grimes, H.D, Kang, C.
登録日2006-06-05
公開日2006-10-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Vegetative Soybean Lipoxygenase Vlx-B and Vlx-D, and Comparisons with Seed Isoforms Lox-1 and Lox-3.
Proteins, 65, 2006
2IUK
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Crystal structure of Soybean Lipoxygenase-D
分子名称: FE (III) ION, SEED LIPOXYGENASE
著者Youn, B, Sellhorn, G.E, Mirchel, R.J, Gaffney, B.J, Grimes, H.D, Kang, C.
登録日2006-06-05
公開日2006-10-11
最終更新日2022-05-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Vegetative Soybean Lipoxygenase Vlx-B and Vlx-D, and Comparisons with Seed Isoforms Lox-1 and Lox-3.
Proteins, 65, 2006
4WFO
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manganese-substituted soybean lipoxygenase-1
分子名称: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ...
著者Carr, C.A.M, Scouras, A.D, Klinman, J.P.
登録日2014-09-16
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Direct detection of active-site geometries in soybean lipoxygenase-1 by ENDOR
To Be Published
1RP1
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DOG PANCREATIC LIPASE RELATED PROTEIN 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PANCREATIC LIPASE RELATED PROTEIN 1
著者Roussel, A, Cambillau, C.
登録日1998-04-02
公開日1998-06-17
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Reactivation of the totally inactive pancreatic lipase RP1 by structure-predicted point mutations.
Proteins, 32, 1998
1YGE
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LIPOXYGENASE-1 (SOYBEAN) AT 100K
分子名称: FE (III) ION, LIPOXYGENASE-1
著者Minor, W, Steczko, J, Stec, B, Otwinowski, Z, Bolin, J.T, Walter, R, Axelrod, B.
登録日1996-06-04
公開日1997-07-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution.
Biochemistry, 35, 1996
1RRL
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Soybean Lipoxygenase (LOX-3) at 93K at 2.0 A resolution
分子名称: FE (II) ION, Seed lipoxygenase-3
著者Borbulevych, O.Y, Jankun, J, Skrzypczak-Jankun, E.
登録日2003-12-08
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Effect of crystal freezing and small-molecule binding on internal cavity size in a large protein: X-ray and docking studies of lipoxygenase at ambient and low temperature at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 62, 2006
1Y4K
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Lipoxygenase-1 (Soybean) at 100K, N694G Mutant
分子名称: 1,2-ETHANEDIOL, ACETATE ION, FE (II) ION, ...
著者Chruszcz, M, Segraves, E, Holman, T.R, Minor, W.
登録日2004-12-01
公開日2005-12-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Kinetic, spectroscopic, and structural investigations of the soybean lipoxygenase-1 first-coordination sphere mutant, Asn694Gly.
Biochemistry, 45, 2006
3BNE
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Lipoxygenase-1 (Soybean) I553A Mutant
分子名称: FE (III) ION, Seed lipoxygenase-1
著者Tomchick, D.R.
登録日2007-12-14
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008

 

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