1CA1
 
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3CWZ
 | | Structure of RAB6(GTP)-R6IP1 complex | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab6-interacting protein 1, ... | | 著者 | Recacha, R, Houdusse, A, Goud, B, Khan, A.R. | | 登録日 | 2008-04-23 | | 公開日 | 2008-11-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain.
Structure, 17, 2009
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4WFO
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1IK3
 | | LIPOXYGENASE-3 (SOYBEAN) COMPLEX WITH 13(S)-HYDROPEROXY-9(Z),11(E)-OCTADECADIENOIC ACID | | 分子名称: | (TRANS-12,13-EPOXY)-11-HYDROXY-9(Z)-OCTADECENOIC ACID, (TRANS-12,13-EPOXY)-9-HYDROXY-10(E)-OCTADECENOIC ACID, 13(R)-HYDROPEROXY-9(Z),11(E)-OCTADECADIENOIC ACID, ... | | 著者 | Skrzypczak-Jankun, E, Funk Jr, M.O. | | 登録日 | 2001-05-01 | | 公開日 | 2001-11-14 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structure of a purple lipoxygenase.
J.Am.Chem.Soc., 123, 2001
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6A70
 | | Structure of the human PKD1/PKD2 complex | | 分子名称: | Polycystin-1, Polycystin-2 | | 著者 | Su, Q, Hu, F, Ge, X, Lei, J, Yu, S, Wang, T, Zhou, Q, Mei, C, Shi, Y. | | 登録日 | 2018-06-29 | | 公開日 | 2018-08-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of the human PKD1-PKD2 complex.
Science, 361, 2018
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5EEO
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6U7M
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4WHA
 | | Lipoxygenase-1 (soybean) L546A/L754A mutant | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, FE (III) ION, ... | | 著者 | Scouras, A.D, Carr, C.A.M, Hu, S, Klinman, J.P. | | 登録日 | 2014-09-21 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Extremely elevated room-temperature kinetic isotope effects quantify the critical role of barrier width in enzymatic C-H activation.
J.Am.Chem.Soc., 136, 2014
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7LAF
 | | 15-lipoxygenase-2 loop mutant bound to imidazole-based inhibitor | | 分子名称: | 3-{[(4-methylphenyl)methyl]sulfanyl}-1-phenyl-1H-1,2,4-triazole, MANGANESE (II) ION, Polyunsaturated fatty acid lipoxygenase ALOX15B | | 著者 | Newcomer, M.E, Gilbert, N.C, Neau, D.B. | | 登録日 | 2021-01-06 | | 公開日 | 2022-01-19 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2.
Bioorg.Med.Chem., 46, 2021
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6E7K
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4NRE
 | | The structure of human 15-lipoxygenase-2 with a substrate mimic | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Arachidonate 15-lipoxygenase B, CALCIUM ION, ... | | 著者 | Kobe, M.J, Neau, D.B, Mitchell, C.E, Bartlett, S.G, Newcomer, M.E. | | 登録日 | 2013-11-26 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | The structure of human 15-lipoxygenase-2 with a substrate mimic.
J.Biol.Chem., 289, 2014
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1W52
 | | Crystal structure of a proteolyzed form of pancreatic lipase related protein 2 from horse | | 分子名称: | CALCIUM ION, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, PANCREATIC LIPASE RELATED PROTEIN 2 | | 著者 | Mancheno, J.M, Jayne, S, Kerfelec, B, Chapus, C, Crenon, I, Hermoso, J.A. | | 登録日 | 2004-08-04 | | 公開日 | 2006-07-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Crystalization of a Proteolyzed Form of the Horse Pancreatic Lipase-Related Protein 2: Structural Basis for the Specific Detergent Requirement.
Acta Crystallogr.,Sect.D, 60, 2004
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8I6Y
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2FNQ
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4QWT
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1BU8
 | | RAT PANCREATIC LIPASE RELATED PROTEIN 2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (PANCREATIC LIPASE RELATED PROTEIN 2) | | 著者 | Roussel, A, Cambillau, C. | | 登録日 | 1998-09-14 | | 公開日 | 1998-12-23 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure and activity of rat pancreatic lipase-related protein 2.
J.Biol.Chem., 273, 1998
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2IUJ
 | | Crystal Structure of Soybean Lipoxygenase-B | | 分子名称: | FE (III) ION, LIPOXYGENASE L-5 | | 著者 | Youn, B, Sellhorn, G.E, Mirchel, R.J, Gaffney, B.J, Grimes, H.D, Kang, C. | | 登録日 | 2006-06-05 | | 公開日 | 2006-10-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structures of Vegetative Soybean Lipoxygenase Vlx-B and Vlx-D, and Comparisons with Seed Isoforms Lox-1 and Lox-3.
Proteins, 65, 2006
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2IUK
 | | Crystal structure of Soybean Lipoxygenase-D | | 分子名称: | FE (III) ION, SEED LIPOXYGENASE | | 著者 | Youn, B, Sellhorn, G.E, Mirchel, R.J, Gaffney, B.J, Grimes, H.D, Kang, C. | | 登録日 | 2006-06-05 | | 公開日 | 2006-10-11 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structures of Vegetative Soybean Lipoxygenase Vlx-B and Vlx-D, and Comparisons with Seed Isoforms Lox-1 and Lox-3.
Proteins, 65, 2006
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3O8Y
 | | Stable-5-Lipoxygenase | | 分子名称: | Arachidonate 5-lipoxygenase, FE (II) ION | | 著者 | Newcomer, M.E, Gilbert, N.C, Bartlett, S.G, Waight, M.T, Neau, D.B, Boeglin, W.E, Brash, A.R. | | 登録日 | 2010-08-03 | | 公開日 | 2011-01-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.389 Å) | | 主引用文献 | The structure of human 5-lipoxygenase.
Science, 331, 2011
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1YGE
 | | LIPOXYGENASE-1 (SOYBEAN) AT 100K | | 分子名称: | FE (III) ION, LIPOXYGENASE-1 | | 著者 | Minor, W, Steczko, J, Stec, B, Otwinowski, Z, Bolin, J.T, Walter, R, Axelrod, B. | | 登録日 | 1996-06-04 | | 公開日 | 1997-07-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution.
Biochemistry, 35, 1996
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1Y4K
 | | Lipoxygenase-1 (Soybean) at 100K, N694G Mutant | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, FE (II) ION, ... | | 著者 | Chruszcz, M, Segraves, E, Holman, T.R, Minor, W. | | 登録日 | 2004-12-01 | | 公開日 | 2005-12-13 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Kinetic, spectroscopic, and structural investigations of the soybean lipoxygenase-1 first-coordination sphere mutant, Asn694Gly.
Biochemistry, 45, 2006
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6N2W
 | | The structure of Stable-5-Lipoxygenase bound to NDGA | | 分子名称: | 4-[(2R,3S)-3-[(3,4-DIHYDROXYPHENYL)METHYL]-2-METHYLBUTYL]BENZENE-1,2-DIOL, Arachidonate 5-lipoxygenase, FE (II) ION | | 著者 | Newcomer, M.E, Gilbert, N.C, Neau, D.B. | | 登録日 | 2018-11-14 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products.
Nat.Chem.Biol., 16, 2020
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6NCF
 | | The structure of Stable-5-Lipoxygenase bound to AKBA | | 分子名称: | (3alpha,8alpha,17alpha,18alpha)-3-(acetyloxy)-11-oxours-12-en-23-oic acid, Arachidonate 5-lipoxygenase, FE (II) ION | | 著者 | Newcomer, M.E, Gilbert, N.C, Neau, D.B. | | 登録日 | 2018-12-11 | | 公開日 | 2020-05-13 | | 最終更新日 | 2020-07-08 | | 実験手法 | X-RAY DIFFRACTION (2.871 Å) | | 主引用文献 | Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products.
Nat.Chem.Biol., 16, 2020
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3PZW
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6OB0
 | | Compound 2 bound structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in HEK293-F cells | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Arora, R, Horton, P.A, Benson, T.E, Romanowski, M.J. | | 登録日 | 2019-03-19 | | 公開日 | 2019-05-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Structure of lipoprotein lipase in complex with GPIHBP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
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