6E7K

Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma triglyceride hydrolysis

Summary for 6E7K

Entry DOI	10.2210/pdb6e7k/pdb
Descriptor	Lipoprotein lipase, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	hydrolase-cofactor complex, lipid degradation, hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	132621.95
Authors	Birrane, G.,Meiyappan, M. (deposition date: 2018-07-26, release date: 2018-12-19, Last modification date: 2023-10-11)
Primary citation	Birrane, G.,Beigneux, A.P.,Dwyer, B.,Strack-Logue, B.,Kristensen, K.K.,Francone, O.L.,Fong, L.G.,Mertens, H.D.T.,Pan, C.Q.,Ploug, M.,Young, S.G.,Meiyappan, M. Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis. Proc. Natl. Acad. Sci. U.S.A., 116:1723-1732, 2019 Cited by PubMed: 30559189 DOI: 10.1073/pnas.1817984116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation