4NRE

The structure of human 15-lipoxygenase-2 with a substrate mimic

Summary for 4NRE

Entry DOI	10.2210/pdb4nre/pdb
Descriptor	Arachidonate 15-lipoxygenase B, FE (II) ION, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ... (7 entities in total)
Functional Keywords	calcium binding, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Isoform A: Nucleus. Cytoplasm, cytosol: O15296
Total number of polymer chains	1
Total formula weight	80282.80
Authors	Kobe, M.J.,Neau, D.B.,Mitchell, C.E.,Bartlett, S.G.,Newcomer, M.E. (deposition date: 2013-11-26, release date: 2014-02-12, Last modification date: 2024-02-28)
Primary citation	Kobe, M.J.,Neau, D.B.,Mitchell, C.E.,Bartlett, S.G.,Newcomer, M.E. The structure of human 15-lipoxygenase-2 with a substrate mimic. J.Biol.Chem., 289:8562-8569, 2014 Cited by PubMed: 24497644 DOI: 10.1074/jbc.M113.543777 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.63 Å)

Structure validation