4WHA

Lipoxygenase-1 (soybean) L546A/L754A mutant

Summary for 4WHA

Entry DOI	10.2210/pdb4wha/pdb
Related	3PZW
Descriptor	Seed linoleate 13S-lipoxygenase-1, FE (III) ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	lipoxygenase, tunneling, c-h activation, oxidoreductase
Biological source	Glycine max (Soybean)
Total number of polymer chains	1
Total formula weight	95400.67
Authors	Scouras, A.D.,Carr, C.A.M.,Hu, S.,Klinman, J.P. (deposition date: 2014-09-21, release date: 2014-11-12, Last modification date: 2023-09-27)
Primary citation	Hu, S.,Sharma, S.C.,Scouras, A.D.,Soudackov, A.V.,Carr, C.A.,Hammes-Schiffer, S.,Alber, T.,Klinman, J.P. Extremely elevated room-temperature kinetic isotope effects quantify the critical role of barrier width in enzymatic C-H activation. J.Am.Chem.Soc., 136:8157-8160, 2014 Cited by PubMed: 24884374 DOI: 10.1021/ja502726s PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation