PDB: 95 件ウェブページステータス検索Chemie searchBIRD

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5FIF	Carboxyltransferase domain of a single-chain bacterial carboxylase 分子名称: 1,2-ETHANEDIOL, Carboxylase 著者 Hagmann, A, Hunkeler, M, Stuttfeld, E, Maier, T. 登録日 2015-12-23 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.494 Å) 主引用文献 Hybrid Structure of a Dynamic Single-Chain Carboxylase from Deinococcus radiodurans. Structure, 24, 2016
4G2R	Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor haloxyfop from Mycobacterium tuberculosis 分子名称: (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid, AccD6, Carboxyltransferase beta-subunit of Acyl-CoA Carboxylase 著者 Reddy, M.C.M, Bruning, J.B, Thurman, C, Sherekar, M, Valluru, S, Ehrenfeld, H, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2012-07-12 公開日 2014-02-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structure, Activity, and Inhibition of the Carboxyltransferase beta-Subunit of Acetyl Coenzyme A Carboxylase (AccD6) from Mycobacterium tuberculosis. Antimicrob.Agents Chemother., 58, 2014
1X0U	Crystal Structure of the carboxyl transferase subunit of putative PCC of Sulfolobus tokodaii 分子名称: hypothetical methylmalonyl-CoA decarboxylase alpha subunit 著者 Kakuta, Y, Sueda, S, Kondo, H. 登録日 2005-03-29 公開日 2006-07-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the carboxyl transferase subunit of putative PCC of Sulfolobus tokodaii To be Published
4FB8	Crystal Structure of apo Acyl-CoA Carboxylase 分子名称: Probable propionyl-CoA carboxylase beta chain 6 著者 Reddy, M.C.M, Bruning, J.B, Sherekar, M, Valluru, S, Ehrenfeld, H, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2012-05-22 公開日 2014-02-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure, Activity, and Inhibition of the Carboxyltransferase beta-Subunit of Acetyl Coenzyme A Carboxylase (AccD6) from Mycobacterium tuberculosis. Antimicrob.Agents Chemother., 58, 2014
4ASI	Crystal structure of human ACACA C-terminal domain 分子名称: ACETYL-COA CARBOXYLASE 1 著者 Froese, D.S, Muniz, J.R.C, Kiyani, W, Krojer, T, Vollmar, M, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U, Yue, W.W. 登録日 2012-05-01 公開日 2012-08-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of Human Acaca C-Terminal Domain To be Published
4L6W	Carboxyltransferase subunit (AccD6) of Mycobacterium tuberculosis acetyl-CoA carboxylase 分子名称: Probable propionyl-CoA carboxylase beta chain 6 著者 Anandhakrishnan, M, Ehebauer, M.T, Wilmanns, M. 登録日 2013-06-13 公開日 2013-07-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural analysis of the carboxyltransferase subunit of Mycobacterium tuberculosis acetyl-CoA carboxylase To be Published
6TZV	Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor Phenyl-Cyclodiaone from Mycobacterium tuberculosis 分子名称: 4'-[(6-chloro-1,3-benzothiazol-2-yl)oxy]-6-hydroxy-4,4-dimethyl-4,5-dihydro[1,1'-biphenyl]-2(3H)-one, Probable propionyl-CoA carboxylase beta chain 6 著者 Reddy, M.C.M, Zhou, N, Sacchettini, J, TB Structural Genomics Consortium (TBSGC) 登録日 2019-08-13 公開日 2020-08-19 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.388 Å) 主引用文献 Novel herbicidal derivatives that inhibit carboxyltransferase subunit of the acetyl-CoA carboxylase in Mycobacterium tuberculosis To Be Published
4Q0G	Crystal structure of beta subunit of acyl-CoA carboxylase AccD1 from Mycobacterium tuberculosis 分子名称: GLYCEROL, Probable acetyl-/propionyl-CoA carboxylase (Beta subunit) AccD1 著者 Bie, H.Y, Yin, J, James, M.N.G, TB Structural Genomics Consortium (TBSGC) 登録日 2014-04-02 公開日 2016-04-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Crystal structure of Beta subunit of acyl-CoA carboxylase AccD1 from Mycobacterium tuberculosis To be Published
4WZ8	Crystal structure of human-yeast chimera acetyl coA carboxylase CT domain bound to Compound 6 分子名称: 1'-(2H-indazol-5-ylcarbonyl)-1-(propan-2-yl)-1,4-dihydrospiro[indazole-5,4'-piperidin]-7(6H)-one, Acetyl-CoA carboxylase 著者 Vajdos, F.F. 登録日 2014-11-18 公開日 2014-12-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes. J.Med.Chem., 57, 2014
4WYO	Crystal structure of human-yeast chimera acetyl coA carboxylase CT domain bound to Compound 1 分子名称: 2'-tert-butyl-1-(2H-indazol-5-ylcarbonyl)-2'H-spiro[piperidine-4,5'-pyrano[3,2-c]pyrazol]-7'(6'H)-one, Acetyl-CoA carboxylase 著者 Vajdos, F.F. 登録日 2014-11-17 公開日 2015-01-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes. J.Med.Chem., 57, 2014
3FF6	Human ACC2 CT domain with CP-640186 分子名称: (3R)-1'-(9-ANTHRYLCARBONYL)-3-(MORPHOLIN-4-YLCARBONYL)-1,4'-BIPIPERIDINE, Acetyl-CoA carboxylase 2 著者 Williams, S.P, Madauss, K.P, Burkhart, W.A. 登録日 2008-12-02 公開日 2009-05-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist. Acta Crystallogr.,Sect.D, 65, 2009
7W5U	Acetyl-CoA Carboxylase-AccB 分子名称: Acetyl-CoA carboxylase complex, beta-chain, GLYCEROL, ... 著者 Ali, I, Zheng, J. 登録日 2021-11-30 公開日 2022-04-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Crystal structure of Acetyl-CoA carboxylase (AccB) from Streptomyces antibioticus and insights into the substrate-binding through in silico mutagenesis and biophysical investigations. Comput Biol Med, 145, 2022
3MFM	Crystal Structures and Mutational Analyses of Acyl-CoA Carboxylase Subunit of Streptomyces coelicolor 分子名称: Propionyl-CoA carboxylase complex B subunit 著者 Diacovich, L, Arabolaza, A, Shillito, E.M, Lin, T.-W, Mitchell, D.L, Melgar, M.M. 登録日 2010-04-02 公開日 2010-10-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Crystal structures and mutational analyses of acyl-CoA carboxylase beta subunit of Streptomyces coelicolor. Biochemistry, 49, 2010
3GF7	Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum apoprotein 分子名称: Glutaconyl-CoA decarboxylase subunit A, SULFATE ION 著者 Kress, D, Brugel, D, Buckel, W, Essen, L.-O. 登録日 2009-02-26 公開日 2009-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 An asymmetric model for Na+-translocating glutaconyl-CoA decarboxylases J.Biol.Chem., 284, 2009
6PK2	CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS 分子名称: 2-{4-[(6-fluoro-1,3-benzothiazol-2-yl)oxy]-2-hydroxyphenyl}-N-methylacetamide, Propionyl-CoA carboxylase subunit beta 著者 Reddy, M.C.M, Nian, Z, Michele, T.C.B, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2019-06-28 公開日 2020-07-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.402 Å) 主引用文献 Elucidating the Inhibition and specificity of binding of herbicidal aryloxyphenoxypropionates derivatives to Mycobacterium tuberculosis carboxyltransferase domain of acetyl-coenzyme A(AccD6). To Be Published
6P7U	CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P FROM MYCOBACTERIUM TUBERCULOSIS 分子名称: (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid, Probable propionyl-CoA carboxylase beta chain 6 著者 Reddy, M.C.M, Sacchettini, J.C, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-06-06 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.198 Å) 主引用文献 Inhibition of Mycobacterium tuberculosis acetyl-CoA carboxyltransferase(AccD6)d omain of acetyl-coenzyme A carboxylase by quizalofop-p To Be Published
2BZR	Crystal structure of accD5 (Rv3280), an acyl-CoA carboxylase beta- subunit from Mycobacterium tuberculosis 分子名称: PROPIONYL-COA CARBOXYLASE BETA CHAIN 5 著者 Holton, S.J. 登録日 2005-08-22 公開日 2007-01-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Diversity in the Six-Fold Redundant Set of Acyl-Coa Carboxyltransferases in Mycobacterium Tuberculosis. FEBS Lett., 580, 2006
6PRW	CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P DERIVATIVE FROM MYCOBACTERIUM TUBERCULOSIS 分子名称: Propionyl-CoA carboxylase subunit beta, {4-[(6-chloroquinoxalin-2-yl)oxy]phenyl}acetic acid 著者 Reddy, M.C.M, Nian, Z, Michele, S.T.C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2019-07-11 公開日 2020-07-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.609 Å) 主引用文献 CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P DEVERIVATIVE FROM MYCOBACTERIUM TUBERCULOSIS To Be Published
3U9R	Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC), beta subunit 分子名称: Methylcrotonyl-CoA carboxylase, beta-subunit, PENTAETHYLENE GLYCOL, ... 著者 Huang, C.S, Tong, L. 登録日 2011-10-19 公開日 2011-12-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase Nature, 481, 2012
3TVW	Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 4 分子名称: Acetyl-CoA carboxylase, [4-(2H-chromen-3-ylmethyl)piperazin-1-yl]-[3-(1H-pyrazol-5-yl)phenyl]methanone 著者 Rajamohan, F, Marr, E, Reyes, A, Landro, J.A, Anderson, M.D, Corbett, J.W, Dirico, K.J, Harwood, J.H, Tu, M, Vajdos, F.F. 登録日 2011-09-20 公開日 2011-10-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site Conversion. J.Biol.Chem., 286, 2011
1OD2	Acetyl-CoA Carboxylase Carboxyltransferase Domain 分子名称: ACETYL COENZYME *A, ACETYL-COENZYME A CARBOXYLASE, ADENINE 著者 Zhang, H, Yang, Z, Shen, Y, Tong, L. 登録日 2003-02-12 公開日 2003-04-03 最終更新日 2018-06-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase. Science, 299, 2003
3PGQ	Crystal Structure of the Carboxyltransferase Domain of S. cerevisiae Acetyl CoA Carboxylase in Complex with Pinoxaden 分子名称: 8-(2-ethenyl-6-ethyl-4-methylphenyl)tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione, Acetyl-CoA carboxylase 著者 Tong, L, Yu, L.P.C, Kim, Y.S. 登録日 2010-11-02 公開日 2010-12-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by pinoxaden. Proc.Natl.Acad.Sci.USA, 107, 2010
1PIX	Crystal structure of the carboxyltransferase subunit of the bacterial ion pump glutaconyl-coenzyme A decarboxylase 分子名称: FORMIC ACID, Glutaconyl-CoA decarboxylase A subunit, SULFATE ION 著者 Wendt, K.S, Schall, I, Huber, R, Buckel, W, Jacob, U. 登録日 2003-05-30 公開日 2003-08-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the carboxyltransferase subunit of the bacterial sodium ion pump glutaconyl-coenzyme A decarboxylase Embo J., 22, 2003
5CTC	Humanized yeast ACC carboxyltransferase domain bound to tert-butyl 7-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate 分子名称: Acetyl-CoA carboxylase, SULFATE ION, tert-butyl 7-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate 著者 Vajdos, F.F. 登録日 2015-07-23 公開日 2015-10-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase. Bioorg.Med.Chem.Lett., 25, 2015
1ON3	Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core (with methylmalonyl-coenzyme a and methylmalonic acid bound) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CADMIUM ION, METHYLMALONIC ACID, ... 著者 Hall, P.R, Wang, Y.-F, Rivera-Hainaj, R.E, Zheng, X, Pustai-Carey, M, Carey, P.R, Yee, V.C. 登録日 2003-02-26 公開日 2003-05-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core Embo J., 22, 2003

 

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