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5FIF
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BU of 5fif by Molmil
Carboxyltransferase domain of a single-chain bacterial carboxylase
分子名称: 1,2-ETHANEDIOL, Carboxylase
著者Hagmann, A, Hunkeler, M, Stuttfeld, E, Maier, T.
登録日2015-12-23
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.494 Å)
主引用文献Hybrid Structure of a Dynamic Single-Chain Carboxylase from Deinococcus radiodurans.
Structure, 24, 2016
4G2R
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BU of 4g2r by Molmil
Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor haloxyfop from Mycobacterium tuberculosis
分子名称: (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid, AccD6, Carboxyltransferase beta-subunit of Acyl-CoA Carboxylase
著者Reddy, M.C.M, Bruning, J.B, Thurman, C, Sherekar, M, Valluru, S, Ehrenfeld, H, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2012-07-12
公開日2014-02-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structure, Activity, and Inhibition of the Carboxyltransferase beta-Subunit of Acetyl Coenzyme A Carboxylase (AccD6) from Mycobacterium tuberculosis.
Antimicrob.Agents Chemother., 58, 2014
1X0U
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BU of 1x0u by Molmil
Crystal Structure of the carboxyl transferase subunit of putative PCC of Sulfolobus tokodaii
分子名称: hypothetical methylmalonyl-CoA decarboxylase alpha subunit
著者Kakuta, Y, Sueda, S, Kondo, H.
登録日2005-03-29
公開日2006-07-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the carboxyl transferase subunit of putative PCC of Sulfolobus tokodaii
To be Published
4FB8
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BU of 4fb8 by Molmil
Crystal Structure of apo Acyl-CoA Carboxylase
分子名称: Probable propionyl-CoA carboxylase beta chain 6
著者Reddy, M.C.M, Bruning, J.B, Sherekar, M, Valluru, S, Ehrenfeld, H, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2012-05-22
公開日2014-02-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure, Activity, and Inhibition of the Carboxyltransferase beta-Subunit of Acetyl Coenzyme A Carboxylase (AccD6) from Mycobacterium tuberculosis.
Antimicrob.Agents Chemother., 58, 2014
4ASI
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BU of 4asi by Molmil
Crystal structure of human ACACA C-terminal domain
分子名称: ACETYL-COA CARBOXYLASE 1
著者Froese, D.S, Muniz, J.R.C, Kiyani, W, Krojer, T, Vollmar, M, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U, Yue, W.W.
登録日2012-05-01
公開日2012-08-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Human Acaca C-Terminal Domain
To be Published
4L6W
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BU of 4l6w by Molmil
Carboxyltransferase subunit (AccD6) of Mycobacterium tuberculosis acetyl-CoA carboxylase
分子名称: Probable propionyl-CoA carboxylase beta chain 6
著者Anandhakrishnan, M, Ehebauer, M.T, Wilmanns, M.
登録日2013-06-13
公開日2013-07-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural analysis of the carboxyltransferase subunit of Mycobacterium tuberculosis acetyl-CoA carboxylase
To be Published
6TZV
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BU of 6tzv by Molmil
Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor Phenyl-Cyclodiaone from Mycobacterium tuberculosis
分子名称: 4'-[(6-chloro-1,3-benzothiazol-2-yl)oxy]-6-hydroxy-4,4-dimethyl-4,5-dihydro[1,1'-biphenyl]-2(3H)-one, Probable propionyl-CoA carboxylase beta chain 6
著者Reddy, M.C.M, Zhou, N, Sacchettini, J, TB Structural Genomics Consortium (TBSGC)
登録日2019-08-13
公開日2020-08-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.388 Å)
主引用文献Novel herbicidal derivatives that inhibit carboxyltransferase subunit of the acetyl-CoA carboxylase in Mycobacterium tuberculosis
To Be Published
4Q0G
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BU of 4q0g by Molmil
Crystal structure of beta subunit of acyl-CoA carboxylase AccD1 from Mycobacterium tuberculosis
分子名称: GLYCEROL, Probable acetyl-/propionyl-CoA carboxylase (Beta subunit) AccD1
著者Bie, H.Y, Yin, J, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2014-04-02
公開日2016-04-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of Beta subunit of acyl-CoA carboxylase AccD1 from Mycobacterium tuberculosis
To be Published
4WZ8
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BU of 4wz8 by Molmil
Crystal structure of human-yeast chimera acetyl coA carboxylase CT domain bound to Compound 6
分子名称: 1'-(2H-indazol-5-ylcarbonyl)-1-(propan-2-yl)-1,4-dihydrospiro[indazole-5,4'-piperidin]-7(6H)-one, Acetyl-CoA carboxylase
著者Vajdos, F.F.
登録日2014-11-18
公開日2014-12-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes.
J.Med.Chem., 57, 2014
4WYO
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BU of 4wyo by Molmil
Crystal structure of human-yeast chimera acetyl coA carboxylase CT domain bound to Compound 1
分子名称: 2'-tert-butyl-1-(2H-indazol-5-ylcarbonyl)-2'H-spiro[piperidine-4,5'-pyrano[3,2-c]pyrazol]-7'(6'H)-one, Acetyl-CoA carboxylase
著者Vajdos, F.F.
登録日2014-11-17
公開日2015-01-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes.
J.Med.Chem., 57, 2014
3FF6
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BU of 3ff6 by Molmil
Human ACC2 CT domain with CP-640186
分子名称: (3R)-1'-(9-ANTHRYLCARBONYL)-3-(MORPHOLIN-4-YLCARBONYL)-1,4'-BIPIPERIDINE, Acetyl-CoA carboxylase 2
著者Williams, S.P, Madauss, K.P, Burkhart, W.A.
登録日2008-12-02
公開日2009-05-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist.
Acta Crystallogr.,Sect.D, 65, 2009
7W5U
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BU of 7w5u by Molmil
Acetyl-CoA Carboxylase-AccB
分子名称: Acetyl-CoA carboxylase complex, beta-chain, GLYCEROL, ...
著者Ali, I, Zheng, J.
登録日2021-11-30
公開日2022-04-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Crystal structure of Acetyl-CoA carboxylase (AccB) from Streptomyces antibioticus and insights into the substrate-binding through in silico mutagenesis and biophysical investigations.
Comput Biol Med, 145, 2022
3MFM
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BU of 3mfm by Molmil
Crystal Structures and Mutational Analyses of Acyl-CoA Carboxylase Subunit of Streptomyces coelicolor
分子名称: Propionyl-CoA carboxylase complex B subunit
著者Diacovich, L, Arabolaza, A, Shillito, E.M, Lin, T.-W, Mitchell, D.L, Melgar, M.M.
登録日2010-04-02
公開日2010-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Crystal structures and mutational analyses of acyl-CoA carboxylase beta subunit of Streptomyces coelicolor.
Biochemistry, 49, 2010
3GF7
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BU of 3gf7 by Molmil
Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum apoprotein
分子名称: Glutaconyl-CoA decarboxylase subunit A, SULFATE ION
著者Kress, D, Brugel, D, Buckel, W, Essen, L.-O.
登録日2009-02-26
公開日2009-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An asymmetric model for Na+-translocating glutaconyl-CoA decarboxylases
J.Biol.Chem., 284, 2009
6PK2
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BU of 6pk2 by Molmil
CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS
分子名称: 2-{4-[(6-fluoro-1,3-benzothiazol-2-yl)oxy]-2-hydroxyphenyl}-N-methylacetamide, Propionyl-CoA carboxylase subunit beta
著者Reddy, M.C.M, Nian, Z, Michele, T.C.B, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2019-06-28
公開日2020-07-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Elucidating the Inhibition and specificity of binding of herbicidal aryloxyphenoxypropionates derivatives to Mycobacterium tuberculosis carboxyltransferase domain of acetyl-coenzyme A(AccD6).
To Be Published
6P7U
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BU of 6p7u by Molmil
CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P FROM MYCOBACTERIUM TUBERCULOSIS
分子名称: (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid, Probable propionyl-CoA carboxylase beta chain 6
著者Reddy, M.C.M, Sacchettini, J.C, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-06-06
公開日2020-06-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Inhibition of Mycobacterium tuberculosis acetyl-CoA carboxyltransferase(AccD6)d omain of acetyl-coenzyme A carboxylase by quizalofop-p
To Be Published
2BZR
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BU of 2bzr by Molmil
Crystal structure of accD5 (Rv3280), an acyl-CoA carboxylase beta- subunit from Mycobacterium tuberculosis
分子名称: PROPIONYL-COA CARBOXYLASE BETA CHAIN 5
著者Holton, S.J.
登録日2005-08-22
公開日2007-01-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Diversity in the Six-Fold Redundant Set of Acyl-Coa Carboxyltransferases in Mycobacterium Tuberculosis.
FEBS Lett., 580, 2006
6PRW
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BU of 6prw by Molmil
CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P DERIVATIVE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称: Propionyl-CoA carboxylase subunit beta, {4-[(6-chloroquinoxalin-2-yl)oxy]phenyl}acetic acid
著者Reddy, M.C.M, Nian, Z, Michele, S.T.C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2019-07-11
公開日2020-07-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.609 Å)
主引用文献CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P DEVERIVATIVE FROM MYCOBACTERIUM TUBERCULOSIS
To Be Published
3U9R
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BU of 3u9r by Molmil
Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC), beta subunit
分子名称: Methylcrotonyl-CoA carboxylase, beta-subunit, PENTAETHYLENE GLYCOL, ...
著者Huang, C.S, Tong, L.
登録日2011-10-19
公開日2011-12-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase
Nature, 481, 2012
3TVW
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BU of 3tvw by Molmil
Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 4
分子名称: Acetyl-CoA carboxylase, [4-(2H-chromen-3-ylmethyl)piperazin-1-yl]-[3-(1H-pyrazol-5-yl)phenyl]methanone
著者Rajamohan, F, Marr, E, Reyes, A, Landro, J.A, Anderson, M.D, Corbett, J.W, Dirico, K.J, Harwood, J.H, Tu, M, Vajdos, F.F.
登録日2011-09-20
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site Conversion.
J.Biol.Chem., 286, 2011
1OD2
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BU of 1od2 by Molmil
Acetyl-CoA Carboxylase Carboxyltransferase Domain
分子名称: ACETYL COENZYME *A, ACETYL-COENZYME A CARBOXYLASE, ADENINE
著者Zhang, H, Yang, Z, Shen, Y, Tong, L.
登録日2003-02-12
公開日2003-04-03
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase.
Science, 299, 2003
3PGQ
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BU of 3pgq by Molmil
Crystal Structure of the Carboxyltransferase Domain of S. cerevisiae Acetyl CoA Carboxylase in Complex with Pinoxaden
分子名称: 8-(2-ethenyl-6-ethyl-4-methylphenyl)tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione, Acetyl-CoA carboxylase
著者Tong, L, Yu, L.P.C, Kim, Y.S.
登録日2010-11-02
公開日2010-12-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by pinoxaden.
Proc.Natl.Acad.Sci.USA, 107, 2010
1PIX
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BU of 1pix by Molmil
Crystal structure of the carboxyltransferase subunit of the bacterial ion pump glutaconyl-coenzyme A decarboxylase
分子名称: FORMIC ACID, Glutaconyl-CoA decarboxylase A subunit, SULFATE ION
著者Wendt, K.S, Schall, I, Huber, R, Buckel, W, Jacob, U.
登録日2003-05-30
公開日2003-08-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the carboxyltransferase subunit of the bacterial sodium ion pump glutaconyl-coenzyme A decarboxylase
Embo J., 22, 2003
5CTC
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BU of 5ctc by Molmil
Humanized yeast ACC carboxyltransferase domain bound to tert-butyl 7-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate
分子名称: Acetyl-CoA carboxylase, SULFATE ION, tert-butyl 7-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate
著者Vajdos, F.F.
登録日2015-07-23
公開日2015-10-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase.
Bioorg.Med.Chem.Lett., 25, 2015
1ON3
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BU of 1on3 by Molmil
Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core (with methylmalonyl-coenzyme a and methylmalonic acid bound)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CADMIUM ION, METHYLMALONIC ACID, ...
著者Hall, P.R, Wang, Y.-F, Rivera-Hainaj, R.E, Zheng, X, Pustai-Carey, M, Carey, P.R, Yee, V.C.
登録日2003-02-26
公開日2003-05-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core
Embo J., 22, 2003

 

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