4FB8

Crystal Structure of apo Acyl-CoA Carboxylase

Summary for 4FB8

• Entry DOI: 10.2210/pdb4fb8/pdb
• Related: 4G2R
• Descriptor: Probable propionyl-CoA carboxylase beta chain 6 (2 entities in total)
• Functional Keywords: structural genomics, tb structural genomics consortium, tbsgc, crotonase fold, acyl-coa carboxylase, ligase, psi-2, protein structure initiative
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 100397.87

Authors

Reddy, M.C.M.,Bruning, J.B.,Sherekar, M.,Valluru, S.,Ehrenfeld, H.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2012-05-22, release date: 2014-02-19, Last modification date: 2023-09-13)

• Primary citation: Reddy, M.C.,Breda, A.,Bruning, J.B.,Sherekar, M.,Valluru, S.,Thurman, C.,Ehrenfeld, H.,Sacchettini, J.C.; Structure, Activity, and Inhibition of the Carboxyltransferase beta-Subunit of Acetyl Coenzyme A Carboxylase (AccD6) from Mycobacterium tuberculosis.; Antimicrob.Agents Chemother., 58:6122-6132, 2014; PubMed: 25092705; DOI: 10.1128/AAC.02574-13

Experimental method

X-RAY DIFFRACTION (3 Å)