6TZV
Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor Phenyl-Cyclodiaone from Mycobacterium tuberculosis
Summary for 6TZV
Entry DOI | 10.2210/pdb6tzv/pdb |
Related | 6PRW |
Descriptor | Probable propionyl-CoA carboxylase beta chain 6, 4'-[(6-chloro-1,3-benzothiazol-2-yl)oxy]-6-hydroxy-4,4-dimethyl-4,5-dihydro[1,1'-biphenyl]-2(3H)-one (3 entities in total) |
Functional Keywords | transferase inhibitor accd6, carboxyltransferase beta-subunit of acyl-coacarboxylase, structural genomics, tb structural genomics consortium, tbsgc, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Total number of polymer chains | 8 |
Total formula weight | 404790.60 |
Authors | Reddy, M.C.M.,Zhou, N.,Sacchettini, J.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2019-08-13, release date: 2020-08-19, Last modification date: 2024-03-13) |
Primary citation | Reddy, M.C.M.,Zhou, N.,Sacchettini, J. Novel herbicidal derivatives that inhibit carboxyltransferase subunit of the acetyl-CoA carboxylase in Mycobacterium tuberculosis To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.388 Å) |
Structure validation
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