4GB0
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2K4D
| E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity | 分子名称: | E3 ubiquitin-protein ligase CBL, ZINC ION | 著者 | Huang, A, De Jong, R.N, Wienk, H, Winkler, S.G, Timmers, H.T.M, Boelens, R. | 登録日 | 2008-06-06 | 公開日 | 2009-01-20 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity J.Mol.Biol., 385, 2009
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2ECW
| Solution structure of the Zinc finger, C3HC4 type (RING finger) domain Tripartite motif protein 30 | 分子名称: | Tripartite motif-containing protein 30, ZINC ION | 著者 | Abe, H, Miyamoto, K, Tochio, N, Yoneyama, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-02-14 | 公開日 | 2008-02-26 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the Zinc finger, C3HC4 type (RING finger) domain Tripartite motif protein 30 To be Published
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5YUF
| Crystal Structure of PML RING tetramer | 分子名称: | Protein PML, ZINC ION | 著者 | Wang, P, Benhend, S, Wu, H, Breitenbach, V, Zhen, T, Jollivet, F, Peres, L, Li, Y, Chen, S, Chen, Z, de THE, H, Meng, G. | 登録日 | 2017-11-22 | 公開日 | 2018-04-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | RING tetramerization is required for nuclear body biogenesis and PML sumoylation. Nat Commun, 9, 2018
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6IR0
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4R7E
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3L11
| Crystal Structure of the Ring Domain of RNF168 | 分子名称: | E3 ubiquitin-protein ligase RNF168, MALONATE ION, ZINC ION | 著者 | Neculai, D, Yermekbayeva, L, Crombet, L, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2009-12-10 | 公開日 | 2010-01-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation. J.Biol.Chem., 287, 2012
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2LDR
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1CHC
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2MWX
| The RING Domain of human Promyelocytic Leukemia Protein (PML) | 分子名称: | Protein PML, ZINC ION | 著者 | Huang, S.Y, Chang, C.F, Fan, P.J, Guntert, P, Shih, H.M, Huang, T.H. | 登録日 | 2014-12-02 | 公開日 | 2015-02-11 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The RING domain of human promyelocytic leukemia protein (PML). J.Biomol.Nmr, 61, 2015
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1BOR
| TRANSCRIPTION FACTOR PML, A PROTO-ONCOPROTEIN, NMR, 1 REPRESENTATIVE STRUCTURE AT PH 7.5, 30 C, IN THE PRESENCE OF ZINC | 分子名称: | TRANSCRIPTION FACTOR PML, ZINC ION | 著者 | Borden, K.L.B, Freemont, P.S. | 登録日 | 1995-09-27 | 公開日 | 1997-04-01 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML. EMBO J., 14, 1995
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5H7R
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5TRB
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6DBO
| Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | 分子名称: | CALCIUM ION, Forward strand of substrate RSS DNA, Recombination activating gene 1 - MBP chimera, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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1FBV
| STRUCTURE OF A CBL-UBCH7 COMPLEX: RING DOMAIN FUNCTION IN UBIQUITIN-PROTEIN LIGASES | 分子名称: | SIGNAL TRANSDUCTION PROTEIN CBL, SULFATE ION, UBIQUITIN-CONJUGATING ENZYME E12-18 KDA UBCH7, ... | 著者 | Zheng, N, Wang, P, Jeffrey, P.D, Pavletich, N.P. | 登録日 | 2000-07-17 | 公開日 | 2000-08-30 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases. Cell(Cambridge,Mass.), 102, 2000
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7LYB
| Cryo-EM structure of the human nucleosome core particle in complex with BRCA1-BARD1-UbcH5c | 分子名称: | BRCA1-associated RING domain protein 1, DNA (146-MER), DNA (147-MER), ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G. | 登録日 | 2021-03-06 | 公開日 | 2021-07-28 | 最終更新日 | 2021-09-01 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. Nature, 596, 2021
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6V0V
| Cryo-EM structure of mouse WT RAG1/2 NFC complex (DNA0) | 分子名称: | CALCIUM ION, DNA (30-MER), V(D)J recombination-activating protein 1, ... | 著者 | Chen, X, Yang, W, Gellert, M. | 登録日 | 2019-11-19 | 公開日 | 2020-01-29 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | 主引用文献 | Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
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1RMD
| RAG1 DIMERIZATION DOMAIN | 分子名称: | RAG1, ZINC ION | 著者 | Bellon, S.F, Rodgers, K.K, Schatz, D.G, Coleman, J.E, Steitz, T.A. | 登録日 | 1997-01-10 | 公開日 | 1997-07-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster. Nat.Struct.Biol., 4, 1997
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6FGA
| Crystal structure of TRIM21 E3 ligase, RING domain in complex with its cognate E2 conjugating enzyme UBE2E1 | 分子名称: | E3 ubiquitin-protein ligase TRIM21, GLYCEROL, Ubiquitin-conjugating enzyme E2 E1, ... | 著者 | Anandapadamanaban, M, Moche, M, Sunnerhagen, M. | 登録日 | 2018-01-10 | 公開日 | 2019-06-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | E3 ubiquitin-protein ligase TRIM21-mediated lysine capture by UBE2E1 reveals substrate-targeting mode of a ubiquitin-conjugating E2. J.Biol.Chem., 294, 2019
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7JZV
| Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome | 分子名称: | BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ... | 著者 | Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E. | 登録日 | 2020-09-02 | 公開日 | 2021-02-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1. Nat.Struct.Mol.Biol., 28, 2021
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1JM7
| Solution structure of the BRCA1/BARD1 RING-domain heterodimer | 分子名称: | BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1, BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, ZINC ION | 著者 | Brzovic, P.S, Rajagopal, P, Hoyt, D.W, King, M.-C, Klevit, R.E. | 登録日 | 2001-07-17 | 公開日 | 2001-10-03 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat.Struct.Biol., 8, 2001
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8IEJ
| RNF20-RNF40/hRad6A-Ub/nucleosome complex | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ... | 著者 | Ai, H, Deng, Z, Sun, M, Du, Y, Pan, M, Liu, L. | 登録日 | 2023-02-15 | 公開日 | 2023-09-06 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A. Mol.Cell, 83, 2023
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3KNV
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7OIM
| Mouse RNF213, with mixed nucleotides bound | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, E3 ubiquitin-protein ligase RNF213, ... | 著者 | Grabarczyk, D, Ahel, J, Clausen, T. | 登録日 | 2021-05-11 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | E3 ubiquitin ligase RNF213 employs a non-canonical zinc finger active site and is allosterically regulated by ATP To Be Published
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7OIK
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