PDB: 437 件ウェブページステータス検索Chemie searchBIRD

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8RVT	Structure of full-length human insulin fibrils 分子名称: Insulin A chain, Insulin B chain 著者 Bardiaux, B, Suladze, S, Reif, B. 登録日 2024-02-02 公開日 2024-05-29 最終更新日 2024-06-12 実験手法 SOLID-STATE NMR 主引用文献 Atomic resolution structure of full-length human insulin fibrils. Proc.Natl.Acad.Sci.USA, 121, 2024
8Z4B	Crystal structure of LysB22-AspB28 insulin analog at ambient structure 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Ayan, E, Demirci, H. 登録日 2024-04-17 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of LysB22-AspB28 insulin analog at ambient structure To Be Published
8ONK	Human insulin in complex with the analytical antibody S1 Fab and the analytical antibody HUI-001 Fab 分子名称: Heavy chain of analytical antibody HUI-001 Fab, Heavy chain of analytical antibody S1 Fab, Insulin A chain, ... 著者 Johansson, E. 登録日 2023-04-03 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (3.403 Å) 主引用文献 Macromolecular structure of insulin and IgE clonality impacts IgE-mediated activation of sensitized basophils To Be Published
8ONI	Human insulin in complex with the analytical antibody S1 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of analytical antibody S1 Fab, Insulin A chain, ... 著者 Johansson, E. 登録日 2023-04-03 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Macromolecular structure of insulin and IgE clonality impacts IgE-mediated activation of sensitized basophils To Be Published
8VJC	Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation. 分子名称: Insulin-like growth factor II, Isoform Short of Insulin receptor 著者 An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. 登録日 2024-01-06 公開日 2024-03-27 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
8VJB	Cryo-EM structure of short form insulin receptor (IR-A) with four IGF2 bound, symmetric conformation. 分子名称: Insulin-like growth factor II, Isoform Short of Insulin receptor 著者 An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. 登録日 2024-01-06 公開日 2024-03-27 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
8U4C	Cryo-EM structure of long form insulin receptor (IR-B) with four IGF2 bound, symmetric conformation. 分子名称: Insulin receptor, Insulin-like growth factor II 著者 An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. 登録日 2023-09-10 公開日 2024-03-27 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
8U4E	Cryo-EM structure of long form insulin receptor (IR-B) with three IGF2 bound, asymmetric conformation. 分子名称: Insulin receptor, Insulin-like growth factor II 著者 An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. 登録日 2023-09-10 公開日 2024-03-27 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
8HGZ	Crystal structure of insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 DeMirci, H, Ayan, E. 登録日 2022-11-16 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Comparative Study of High-Resolution LysB29(N epsilon-myristoyl) des(B30) Insulin Structures Display Novel Dynamic Causal Interrelations in Monomeric-Dimeric Motions Crystals, 13, 2023
8TAN	CryoEM structure of MFRV-VILP bound to IGF1Rzip 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor, ... 著者 Kirk, N.S. 登録日 2023-06-27 公開日 2024-01-17 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression. Mol Metab, 80, 2024
8CLS	Drosophila melanogaster insulin receptor ectodomain in complex with DILP5 分子名称: Insulin-like receptor, Probable insulin-like peptide 5, Probable insulin-like peptide 5 A chain 著者 Viola, C.M, Brzozowski, A.M, Shafi, T. 登録日 2023-02-17 公開日 2023-12-20 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans. Nat Commun, 14, 2023
8HSF	Insulin triple mutant INS-RQD 分子名称: Insulin A chain, Insulin B chain 著者 Kundapura, S.V, Rao, S.S, Kulal, A, Ramagopal, U.A. 登録日 2022-12-19 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insulin triple mutant INS-RQD To Be Published
8HSK	Insulin single mutant INS-Q 分子名称: Insulin A chain, Insulin B chain, SULFATE ION 著者 Rao, S.S, Kundapura, S.V, Kulal, A, Ramagopal, U.A. 登録日 2022-12-19 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Insulin single mutant INS-Q To Be Published
8IPZ	Crystal structure of insulin detemir 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 DeMirci, H, Ayan, E. 登録日 2023-03-15 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of insulin detemir To Be Published
8PJC	Crystal structure of human insulin desB30 precursor with an Alanine-Alanine-Lysine C-peptide in dimer (T2) conformation 分子名称: Insulin 著者 Schluckebier, G, Johansson, E. 登録日 2023-06-23 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PI4	Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in dimer (T2) conformation 分子名称: Insulin B chain,Insulin A chain 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PI6	Crystal structure of the monomeric zinc free human insulin A22K, B3E, B26E, B29R, desB30 precursor with a Ser-Glu-Asp-Trp-Trp-Arg C-peptide and a Glu-Glu-Gly-Glu-Pro-Arg N-terminal extension 分子名称: Insulin B chain,Insulin A chain 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PI5	Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in hexamer (T3R3) conformation 分子名称: CHLORIDE ION, Insulin B chain,Insulin A chain, RESORCINOL, ... 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PJH	Crystal structure of human insulin desB30 precursor with an Aspartate-Glycine-Lysine C-peptide in dimer (T2) conformation 分子名称: Insulin 著者 Schluckebier, G, Johansson, E. 登録日 2023-06-23 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8SBD	Cryo-EM structure of insulin amyloid-like fibril that is composed of two antiparallel protofilaments 分子名称: Insulin A chain, Insulin B chain 著者 Wang, L.W, Hall, C, Uchikawa, E, Chen, D.L, Choi, E, Zhang, X.W, Bai, X.C. 登録日 2023-04-03 公開日 2023-08-30 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis of insulin fibrillation. Sci Adv, 9, 2023
7YRR	Cryo-EM structure of IGF1R with two IGF1 complex 分子名称: Insulin-like growth factor 1 receptor, Isoform 3 of Insulin-like growth factor I 著者 Xi, Z, Cang, W. 登録日 2022-08-10 公開日 2023-08-16 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Cryo-EM structure of IGF1R with two IGF1 complex at 4.3 angstroms resolution To Be Published
7QAC	The T2 structure of polycrystalline cubic human insulin 分子名称: Insulin A chain, Insulin B chain 著者 Karavassili, F, Triandafillidis, D.P, Valmas, A, Spiliopoulou, M, Fili, S, Kontou, P, Bowler, M.W, Von Dreele, R.B, Fitch, A, Margiolaki, I. 登録日 2021-11-16 公開日 2023-06-21 最終更新日 2024-02-07 実験手法 POWDER DIFFRACTION (2.29 Å) 主引用文献 The T 2 structure of polycrystalline cubic human insulin. Acta Crystallogr D Struct Biol, 79, 2023
7Z5Q	Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and p-Hydroxyphenylpyruvate (HPP) 分子名称: Insulin, Insulin A chain, SULFATE ION 著者 van den Elsen, J.M.H, Wahid, A.A, Crennell, S.J. 登録日 2022-03-09 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling To Be Published
7Z5L	Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and dimethyl sulfoxide (DMSO) 分子名称: GLYCEROL, Insulin A chain, Insulin B chain, ... 著者 van den Elsen, J.M.H, Wahid, A.A, Crennell, C. 登録日 2022-03-09 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling To Be Published
8GSG	T3R3 form of Human insulin with single Zn 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Zhu, Z.L. 登録日 2022-09-06 公開日 2023-03-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 T3R3 insulin with single Zn To Be Published

 

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