8ZGT
 
 | | Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri state3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Du, S, Deng, M.J, Xiao, J.Y. | | 登録日 | 2024-05-09 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | Structural insights into the high-affinity IgE receptor Fc epsilon RI complex.
Nature, 633, 2024
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8ZGS
 | | Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri state2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Du, S, Deng, M.J, Xiao, J.Y. | | 登録日 | 2024-05-09 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Structural insights into the high-affinity IgE receptor Fc epsilon RI complex.
Nature, 633, 2024
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8Z7N
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8Y81
 | | Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Du, S, Deng, M.J, Xiao, J.Y. | | 登録日 | 2024-02-05 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structural insights into the high-affinity IgE receptor Fc epsilon RI complex.
Nature, 633, 2024
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8W90
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8TUI
 | | Crystal structure of Fab-Lirilumab bound to KIR2DL3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell immunoglobulin-like receptor 2DL3, Lirilumab Fab Heavy Chain, ... | | 著者 | Lorig-Roach, N, DuBois, R.M. | | 登録日 | 2023-08-16 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural basis for the activity and specificity of the immune checkpoint inhibitor lirilumab.
Sci Rep, 14, 2024
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8SM2
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8SKV
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8SKU
 | | Structure of human SIgA1 in complex with human CD89 (FcaR1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | | 著者 | Liu, Q, Stadtmueller, B.M. | | 登録日 | 2023-04-20 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions.
Nat Commun, 14, 2023
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8QY6
 | | Structure of interleukin 6 (gp130 P496L mutant). | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ... | | 著者 | Gardner, S, Bubeck, D, Jin, Y. | | 登録日 | 2023-10-25 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency.
Nat Commun, 15, 2024
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8QY5
 | | Structure of interleukin 6. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ... | | 著者 | Gardner, S, Bubeck, D, Jin, Y. | | 登録日 | 2023-10-25 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency.
Nat Commun, 15, 2024
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8OVQ
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8K7T
 | | Mouse Fc epsilon RI in complex with mIgE Fc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, High affinity immunoglobulin epsilon receptor subunit beta, ... | | 著者 | Zhang, Z, Yui, M, Ohto, U, Shimizu, T. | | 登録日 | 2023-07-27 | | 公開日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Mouse Fc epsilon RI in complex withMouse Fc epsilon RI in complex with mIgE Fc mIgE Fc
To Be Published
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8J6F
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8IOW
 | | Cryo-EM structure of the sarilumab Fab/IL-6R complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Sarilumab Fab, Interleukin-6 receptor subunit alpha, ... | | 著者 | She, J, Chen, L, Wang, M.X. | | 登録日 | 2023-03-13 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into IL-6 signaling inhibition by therapeutic antibodies.
Cell Rep, 43, 2024
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8GRX
 | | APOE4 receptor in complex with APOE4 NTD | | 分子名称: | Apolipoprotein E, Leukocyte immunoglobulin-like receptor subfamily A member 6 | | 著者 | Zhou, J, Wang, Y, Huang, G, Shi, Y. | | 登録日 | 2022-09-02 | | 公開日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | LilrB3 is a putative cell surface receptor of APOE4.
Cell Res., 33, 2023
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8FYJ
 | | Structure of HIV-1 BG505 SOSIP-HT2 in complex with two CD4 molecules (class I) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | 著者 | Fan, C, Dam, K.A, Bjorkman, P.J. | | 登録日 | 2023-01-26 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Intermediate conformations of CD4-bound HIV-1 Env heterotrimers.
Nature, 623, 2023
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8FYI
 | | Structure of HIV-1 BG505 SOSIP-HT1 in complex with one CD4 molecule | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(6-8)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Fan, C, Dam, K.A, Bjorkman, P.J. | | 登録日 | 2023-01-26 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Intermediate conformations of CD4-bound HIV-1 Env heterotrimers.
Nature, 623, 2023
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8EMA
 | | mouse full length B cell receptor | | 分子名称: | Anti-human Langerin 2G3 lambda chain, B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein beta chain, ... | | 著者 | Ying, D, Xiong, P, Michael, R. | | 登録日 | 2022-09-27 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (8.2 Å) | | 主引用文献 | Structural principles of B cell antigen receptor assembly.
Nature, 612, 2022
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8E4C
 | | IgM BCR fab truncated form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, B-cell antigen receptor complex-associated protein alpha chain,Yellow fluorescent protein, B-cell antigen receptor complex-associated protein beta chain, ... | | 著者 | Dong, Y, Pi, X, Wu, H, Reth, M. | | 登録日 | 2022-08-18 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural principles of B cell antigen receptor assembly.
Nature, 612, 2022
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8DJ7
 | | The complex structure between human IgG1 Fc and its high affinity receptor FcgRI H174R variant | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin gamma Fc receptor I, Ig gamma-1 Fc chain, ... | | 著者 | Lu, J, Sun, P.D. | | 登録日 | 2022-06-30 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Fc gamma RI FG-loop functions as a pH sensitive switch for IgG binding and release.
Front Immunol, 14, 2023
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8DIR
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8DIN
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8DFQ
 | | Ectodomain of full-length KIT(T417I,delta418-419)-SCF dimers | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | | 著者 | Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. | | 登録日 | 2022-06-22 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8DFP
 | | Ectodomain of full-length KIT(DupA502,Y503)-SCF dimers | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | | 著者 | Bertoletti, N, Krimmer, S.G, Mi, W, Schlessinger, J. | | 登録日 | 2022-06-22 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023
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