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6KZH
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BU of 6kzh by Molmil
14-3-3 protein in Complex with CIC S173 phosphorylated peptide
分子名称: 14-3-3 protein theta, CIC pS173 peptide
著者Wen, Y, Shao, Y.
登録日2019-09-24
公開日2020-09-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.645 Å)
主引用文献14-3-3 protein in Complex with CIC S173 phosphorylated peptide
To Be Published
7LQS
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BU of 7lqs by Molmil
Structure of truncated conotoxin CIC
分子名称: Alpha-conotoxin CIC
著者Evans, E.R.J, Daly, N.L.
登録日2021-02-15
公開日2021-04-21
実験手法SOLUTION NMR
主引用文献Synthesis, Structural and Pharmacological Characterizations of CIC, a Novel alpha-Conotoxin with an Extended N-Terminal Tail.
Mar Drugs, 19, 2021
7LQR
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Structure of conotoxin CIC
分子名称: Alpha-conotoxin CIC
著者Evans, E.R.J, Daly, N.L.
登録日2021-02-15
公開日2021-04-21
実験手法SOLUTION NMR
主引用文献Synthesis, Structural and Pharmacological Characterizations of CIC, a Novel alpha-Conotoxin with an Extended N-Terminal Tail.
Mar Drugs, 19, 2021
6KZG
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14-3-3 protein in Complex with CIC S301 phosphorylated peptide
分子名称: 14-3-3 protein theta, ARG-SER-MET-SER-GLU-THR-GLY-THR
著者Wen, Y, Shao, Y.
登録日2019-09-24
公開日2020-09-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献14-3-3 protein in Complex with CIC S301 phosphorylated peptide
To Be Published
6JRP
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BU of 6jrp by Molmil
Crystal structure of CIC-HMG-ETV5-DNA complex
分子名称: DNA (5'-D(*AP*TP*GP*AP*AP*TP*GP*AP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*CP*AP*TP*TP*CP*AP*T)-3'), Protein capicua homolog
著者Song, J.J, Lee, H.
登録日2019-04-05
公開日2019-07-31
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The crystal structure of Capicua HMG-box domain complexed with the ETV5-DNA and its implications for Capicua-mediated cancers.
Febs J., 286, 2019
2M41
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BU of 2m41 by Molmil
Solution Structure of the AXH domain of Ataxin-1 in complex with ligand peptide from Capicua
分子名称: Ataxin-1, Protein capicua homolog
著者de Chiara, C, Kelly, G, Pastore, A.
登録日2013-01-28
公開日2013-12-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Protein-Protein Interactions as a Strategy towards Protein-Specific Drug Design: The Example of Ataxin-1.
Plos One, 8, 2013
4J2J
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BU of 4j2j by Molmil
Crystal structure of AXH domain complex with Capicua
分子名称: Ataxin-1, Protein capicua homolog
著者Song, J.-J, Kim, E.
登録日2013-02-04
公開日2013-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of protein complex formation and reconfiguration by polyglutamine disease protein Ataxin-1 and Capicua
Genes Dev., 27, 2013
4J2L
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BU of 4j2l by Molmil
Crystal Structure of AXH domain complexed with Capicua
分子名称: Ataxin-1, Protein capicua homolog
著者Song, J.-J, Kim, E.
登録日2013-02-04
公開日2013-04-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural basis of protein complex formation and reconfiguration by polyglutamine disease protein Ataxin-1 and Capicua
Genes Dev., 27, 2013
7M5W
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BU of 7m5w by Molmil
Crystal structure of the HMG-C1 domain of human capicua bound to DNA
分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*TP*TP*TP*TP*TP*CP*AP*TP*TP*CP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*TP*AP*TP*GP*AP*AP*TP*GP*AP*AP*AP*AP*AP*GP*C)-3'), ...
著者Webb, J.P, Liew, J.J.M, Gnann, A.D, Dowling, D.P.
登録日2021-03-25
公開日2022-04-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Molecular basis of DNA recognition by the HMG-box-C1 module of Capicua
Biorxiv, 2022
6CTS
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BU of 6cts by Molmil
PROPOSED MECHANISM FOR THE CONDENSATION REACTION OF CITRATE SYNTHASE. 1.9-ANGSTROMS STRUCTURE OF THE TERNARY COMPLEX WITH OXALOACETATE AND CARBOXYMETHYL COENZYME A
分子名称: CITRATE SYNTHASE, CITRYL-THIOETHER-COENZYME *A
著者Karpusas, M, Branchaud, B, Remington, S.J.
登録日1989-11-16
公開日1990-10-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Proposed mechanism for the condensation reaction of citrate synthase: 1.9-A structure of the ternary complex with oxaloacetate and carboxymethyl coenzyme A.
Biochemistry, 29, 1990
7KUI
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BU of 7kui by Molmil
Cryo-EM structure of Rous sarcoma virus cleaved synaptic complex (CSC) with HIV-1 integrase strand transfer inhibitor MK-2048. CIC region of a cluster identified by 3-dimensional variability analysis in cryoSPARC.
分子名称: (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*GP*CP*AP*TP*AP*AP*GP*AP*CP*AP*AP*CP*A)-3'), ...
著者Pandey, K.K, Bera, S, Shi, K, Aihara, H, Grandgenett, D.P.
登録日2020-11-25
公開日2021-03-17
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome.
Commun Biol, 4, 2021
5FCI
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BU of 5fci by Molmil
Structure of the vacant uL3 W255C mutant 80S yeast ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Mailliot, J, Garreau de Loubresse, N, Yusupova, G, Dinman, J.D, Yusupov, M.
登録日2015-12-15
公開日2016-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency.
J.Mol.Biol., 428, 2016
5WIT
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BU of 5wit by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with pikromycin and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution
分子名称: (3R,5R,6S,7S,9R,11E,13S,14R)-14-ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-2,4,10-trioxo-1-oxacyclotetradec-11-en-6-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Almutairi, M.M, Svetlov, M.S, Hansen, D.A, Khabibullina, N.F, Klepacki, D, Kang, H.Y, Sherman, D.H, Vazquez-Laslop, N, Polikanov, Y.S, Mankin, A.S.
登録日2017-07-20
公開日2018-02-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins.
Nucleic Acids Res., 45, 2017
6UCQ
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BU of 6ucq by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome recycling complex
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Zhou, D, Tanzawa, T, Gagnon, M.G, Lin, J.
登録日2019-09-17
公開日2019-12-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis for ribosome recycling by RRF and tRNA.
Nat.Struct.Mol.Biol., 27, 2020
5Y6P
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BU of 5y6p by Molmil
Structure of the phycobilisome from the red alga Griffithsia pacifica
分子名称: ApcD, ApcF, LC, ...
著者Zhang, J, Ma, J.F, Liu, D.S, Sun, S, Sui, S.F.
登録日2017-08-13
公開日2017-11-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of phycobilisome from the red alga Griffithsia pacifica
Nature, 551, 2017
8B3Q
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BU of 8b3q by Molmil
CryoEM structure of the central filamentous region of the f1 filamentous bacteriophage, consisting of the major capsid protein pVIII
分子名称: Capsid protein G8P
著者Conners, R, McLaren, M, Gold, V.A.M.
登録日2022-09-16
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Cryo-electron microscopy of the f1 filamentous phage reveals insights into viral infection and assembly.
Nat Commun, 14, 2023
6OF1
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BU of 6of1 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with dirithromycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.80A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Khabibullina, N.F, Tereshchenkov, A.G, Komarova, E.S, Syroegin, E.A, Shiriaev, D.I, Paleskava, A, Kartsev, V.G, Bogdanov, A.A, Konevega, A.L, Dontsova, O.A, Sergiev, P.V, Osterman, I.A, Polikanov, Y.S.
登録日2019-03-28
公開日2019-04-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Dirithromycin Bound to the Bacterial Ribosome Suggests New Ways for Rational Improvement of Macrolides.
Antimicrob.Agents Chemother., 63, 2019
6FKR
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BU of 6fkr by Molmil
Crystal structure of the dolphin proline-rich antimicrobial peptide Tur1A bound to the Thermus thermophilus 70S ribosome
分子名称: 16 ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Mardirossian, M, Perebaskine, N, Benincasa, M, Gambato, S, Hofmann, S, Huter, P, Muller, C, Hilpert, K, Innis, C.A, Tossi, A, Wilson, D.N.
登録日2018-01-24
公開日2018-03-28
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome.
Cell Chem Biol, 25, 2018
5LYB
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BU of 5lyb by Molmil
Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCPmn
分子名称: 18S rRNA, 25S rRNA, 40S Ribosomal Protein S12, ...
著者Melnikov, S, Mailliot, J.
登録日2016-09-26
公開日2016-11-23
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
4V88
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BU of 4v88 by Molmil
The structure of the eukaryotic ribosome at 3.0 A resolution.
分子名称: 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ...
著者Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M.
登録日2011-10-11
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of the eukaryotic ribosome at 3.0 angstrom resolution.
Science, 334, 2011
4V67
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BU of 4v67 by Molmil
Crystal structure of a translation termination complex formed with release factor RF2.
分子名称: 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ...
著者Korostelev, A, Asahara, H, Lancaster, L, Laurberg, M, Hirschi, A, Noller, H.F.
登録日2008-10-27
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a translation termination complex formed with release factor RF2.
Proc.Natl.Acad.Sci.USA, 105, 2008
4V6G
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BU of 4v6g by Molmil
Initiation complex of 70S ribosome with two tRNAs and mRNA.
分子名称: 16S RRNA (E.COLI NUMBERING), 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Jenner, L.B, Yusupova, G, Yusupov, M.
登録日2009-07-10
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural aspects of messenger RNA reading frame maintenance by the ribosome.
Nat.Struct.Mol.Biol., 17, 2010
4V95
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Crystal structure of YAEJ bound to the 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Gagnon, M.G, Seetharaman, S.V, Bulkley, D.P, Steitz, T.A.
登録日2012-01-27
公開日2014-07-09
最終更新日2018-07-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome.
Science, 335, 2012
7JQL
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BU of 7jql by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-001, mRNA, and deacylated P-site tRNA at 3.00A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M.
登録日2020-08-11
公開日2020-08-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens.
J.Med.Chem., 63, 2020
6XHW
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BU of 6xhw by Molmil
Crystal structure of the A2058-unmethylated Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A- and P-site tRNAs, and deacylated E-site tRNA at 2.50A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Svetlov, M.S, Syroegin, E.A, Aleksandrova, E.V, Atkinson, G.C, Gregory, S.T, Mankin, A.S, Polikanov, Y.S.
登録日2020-06-19
公開日2020-12-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance.
Nat.Chem.Biol., 17, 2021

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