6JRP

Crystal structure of CIC-HMG-ETV5-DNA complex

Summary for 6JRP

• Entry DOI: 10.2210/pdb6jrp/pdb
• Descriptor: Protein capicua homolog, DNA (5'-D(*AP*TP*GP*AP*AP*TP*GP*AP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*CP*AP*TP*TP*CP*AP*T)-3') (3 entities in total)
• Functional Keywords: repressor, protein-dna complex, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 66334.29

Authors

Song, J.J.,Lee, H. (deposition date: 2019-04-05, release date: 2019-07-31, Last modification date: 2020-01-08)

• Primary citation: Lee, H.,Song, J.J.; The crystal structure of Capicua HMG-box domain complexed with the ETV5-DNA and its implications for Capicua-mediated cancers.; Febs J., 286:4951-4963, 2019; PubMed: 31323153; DOI: 10.1111/febs.15008

Experimental method

X-RAY DIFFRACTION (3 Å)