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6OTR
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BU of 6otr by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (AAU)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Pavelich, I.P, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
登録日2019-05-03
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
7MPI
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BU of 7mpi by Molmil
Stm1 bound vacant 80S structure isolated from cbf5-D95A
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Rai, J, Zhao, Y, Li, H.
登録日2021-05-04
公開日2022-05-11
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations.
Structure, 30, 2022
7MPJ
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BU of 7mpj by Molmil
Stm1 bound vacant 80S structure isolated from wild-type
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Rai, J, Zhao, Y, Li, H.
登録日2021-05-04
公開日2022-05-11
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations.
Structure, 30, 2022
6ORD
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BU of 6ord by Molmil
Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to cognate 70S A site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-04-30
公開日2020-06-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OJ2
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BU of 6oj2 by Molmil
Crystal structure of tRNA^ Ala(GGC) bound to the near-cognate 70S A-site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-04-10
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OSI
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BU of 6osi by Molmil
Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (near cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
登録日2019-05-01
公開日2020-10-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (4.14 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6OF1
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BU of 6of1 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with dirithromycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.80A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Khabibullina, N.F, Tereshchenkov, A.G, Komarova, E.S, Syroegin, E.A, Shiriaev, D.I, Paleskava, A, Kartsev, V.G, Bogdanov, A.A, Konevega, A.L, Dontsova, O.A, Sergiev, P.V, Osterman, I.A, Polikanov, Y.S.
登録日2019-03-28
公開日2019-04-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Dirithromycin Bound to the Bacterial Ribosome Suggests New Ways for Rational Improvement of Macrolides.
Antimicrob.Agents Chemother., 63, 2019
5IBB
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BU of 5ibb by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAVal in the A-site
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2016-02-22
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix.
Nucleic Acids Res., 44, 2016
5IB8
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BU of 5ib8 by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNALys with U-G mismatch in the A-site
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2016-02-22
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix.
Nucleic Acids Res., 44, 2016
6ORE
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BU of 6ore by Molmil
Release complex 70S
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fu, Z.
登録日2019-04-30
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OLZ
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BU of 6olz by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-17
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OSQ
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BU of 6osq by Molmil
RF1 accommodated state bound Release complex 70S at long incubation time point
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
登録日2019-05-02
公開日2019-06-26
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OXI
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BU of 6oxi by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (UAA)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
登録日2019-05-13
公開日2019-08-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.495 Å)
主引用文献Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
7N30
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BU of 7n30 by Molmil
Elongating 70S ribosome complex in a hybrid-H2* pre-translocation (PRE-H2*) conformation
分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
著者Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C.
登録日2021-05-30
公開日2021-07-14
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Structural basis of early translocation events on the ribosome.
Nature, 595, 2021
6OLG
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BU of 6olg by Molmil
Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
5W4K
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BU of 5w4k by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with Klebsazolicin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Metelev, M, Osterman, I.A, Ghilarov, D, Khabibullina, N.F, Yakimov, A, Shabalin, K, Utkina, I, Travin, D.Y, Komarova, E.S, Serebryakova, M, Artamonova, T, Khodorkovskii, M, Konevega, A.L, Sergiev, P.V, Severinov, K, Polikanov, Y.S.
登録日2017-06-12
公開日2017-08-30
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.
Nat. Chem. Biol., 13, 2017
6GSK
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BU of 6gsk by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNAThr in the A-site
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Yusupov, M, Yusupova, G.
登録日2018-06-14
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Nucleic Acids Res., 46, 2018
6GSL
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BU of 6gsl by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAArg in the A-site
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Yusupov, M, Yusupova, G.
登録日2018-06-14
公開日2018-07-04
最終更新日2018-09-05
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Nucleic Acids Res., 46, 2018
6OXA
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BU of 6oxa by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S pre-cleavage (AAU)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
登録日2019-05-13
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
6GZ3
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BU of 6gz3 by Molmil
tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-1 (TI-POST-1)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
著者Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V.
登録日2018-07-03
公開日2018-12-05
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
Cell Rep, 25, 2018
6PFY
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BU of 6pfy by Molmil
Membrane Protein Megahertz Crystallography at the European XFEL, Photosystem I at synchrotron to 2.9 A
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
著者Fromme, R.
登録日2019-06-23
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Membrane protein megahertz crystallography at the European XFEL.
Nat Commun, 10, 2019
5VP2
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BU of 5vp2 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with madumycin II and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution
分子名称: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Osterman, I.A, Khabibullina, N.F, Komarova, E.S, Kasatsky, P, Kartsev, V.G, Bogdanov, A.A, Dontsova, O.A, Konevega, A.L, Sergiev, P.V, Polikanov, Y.S.
登録日2017-05-04
公開日2017-06-28
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state.
Nucleic Acids Res., 45, 2017
6J3Z
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BU of 6j3z by Molmil
Structure of C2S1M1-type PSII-FCPII supercomplex from diatom
分子名称: (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'-yl acetate, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
著者Nagao, R, Kato, K, Shen, J.R, Miyazaki, N, Akita, F.
登録日2019-01-07
公開日2019-08-07
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for energy harvesting and dissipation in a diatom PSII-FCPII supercomplex.
Nat.Plants, 5, 2019
5VLZ
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BU of 5vlz by Molmil
Backbone model for phage Qbeta capsid
分子名称: Capsid protein, Maturation protein A2
著者Cui, Z, Zhang, J.
登録日2017-04-26
公開日2017-10-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structures of Q beta virions, virus-like particles, and the Q beta-MurA complex reveal internal coat proteins and the mechanism of host lysis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WDT
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BU of 5wdt by Molmil
70S ribosome-EF-Tu H84A complex with GppNHp
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Brown, Z, Frank, J.
登録日2017-07-06
公開日2018-04-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018

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