PDB: 8717 件ウェブページステータス検索Chemie searchBIRD

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6Y0G	Structure of human ribosome in classical-PRE state 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... 著者 Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. 登録日 2020-02-07 公開日 2020-04-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
6HCQ	Structure of the rabbit collided di-ribosome (collided monosome) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. 登録日 2018-08-16 公開日 2018-10-17 最終更新日 2018-11-14 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
8IR1	human nuclear pre-60S ribosomal particle - State A 分子名称: 28S rRNA, 5.8S rRMA, 5S RNA, ... 著者 Zhang, Y, Gao, N. 登録日 2023-03-17 公開日 2023-08-09 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
5Z56	cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. 登録日 2018-01-17 公開日 2018-09-19 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
6IP8	Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. 登録日 2018-11-02 公開日 2019-05-29 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
5Z57	Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ... 著者 Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. 登録日 2018-01-17 公開日 2018-09-19 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
5A2Q	Structure of the HCV IRES bound to the human ribosome 分子名称: 18S RRNA, HCV IRES, MAGNESIUM ION, ... 著者 Quade, N, Leiundgut, M, Boehringer, D, Heuvel, J.v.d, Ban, N. 登録日 2015-05-21 公開日 2015-07-15 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution Nat.Commun., 6, 2015
6ZMT	SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-03 公開日 2020-08-19 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
8H6J	Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y. 登録日 2022-10-18 公開日 2024-05-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
8H6E	Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. 登録日 2022-10-17 公開日 2024-05-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
7SUK	Structure of Bfr2-Lcp5 Complex Observed in the Small Subunit Processome Isolated from R2TP-depleted Yeast Cells 分子名称: 18S pre-rRNA, 40S ribosomal protein S11-A, 40S ribosomal protein S13, ... 著者 Rai, J, Zhao, Y, Li, H. 登録日 2021-11-17 公開日 2022-07-06 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.99 Å) 主引用文献 Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome. Commun Biol, 5, 2022
7R4X	Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Pellegrino, S, Dent, K.C, Spikes, T, Warren, A.J. 登録日 2022-02-09 公開日 2023-02-22 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.15 Å) 主引用文献 Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 angstrom resolution. Nucleic Acids Res., 51, 2023
6IP6	Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. 登録日 2018-11-02 公開日 2019-05-29 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
8OHD	60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. 登録日 2023-03-21 公開日 2024-02-21 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature, 627, 2024
6ZXH	Cryo-EM structure of a late human pre-40S ribosomal subunit - State H2 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. 登録日 2020-07-29 公開日 2020-12-16 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
6Y6X	Tetracenomycin X bound to the human ribosome 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Buschauer, R, Cheng, J, Berninghausen, O, Beckmann, R, Wilson, D.N. 登録日 2020-02-27 公開日 2020-07-08 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel. Nat.Chem.Biol., 16, 2020
8H6K	Cryo-EM structure of human exon-defined spliceosome in the mature B state. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. 登録日 2022-10-18 公開日 2024-05-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
8H6L	Cryo-EM structure of human exon-defined spliceosome in the early B state. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. 登録日 2022-10-18 公開日 2024-05-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
6HCM	Structure of the rabbit collided di-ribosome (stalled monosome) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. 登録日 2018-08-15 公開日 2018-10-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
5BPC	DNA polymerase beta ternary complex with a templating 5ClC and incoming dATP analog 分子名称: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, DNA (5'-D(*CP*CP*GP*AP*CP*(CDO)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... 著者 Freudenthal, B.D, Wilson, S.H. 登録日 2015-05-28 公開日 2015-08-19 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer. Proc.Natl.Acad.Sci.USA, 112, 2015
8D9D	Human DNA polymerase-alpha/primase elongation complex II bound to primer/template 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3'), DNA polymerase alpha catalytic subunit, ... 著者 He, Q, Baranovskiy, A, Lim, C, Tahirov, T. 登録日 2022-06-09 公開日 2023-04-19 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.59 Å) 主引用文献 Structures of human primosome elongation complexes. Nat.Struct.Mol.Biol., 30, 2023
7DVQ	Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... 著者 Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. 登録日 2021-01-14 公開日 2021-03-31 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Structure of the activated human minor spliceosome. Science, 371, 2021
8CX2	Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 2 分子名称: Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... 著者 Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. 登録日 2022-05-19 公開日 2023-02-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The structural basis for HIV-1 Vif antagonism of human APOBEC3G. Nature, 615, 2023
8CX1	Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 1 分子名称: Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... 著者 Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. 登録日 2022-05-19 公開日 2023-02-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The structural basis for HIV-1 Vif antagonism of human APOBEC3G. Nature, 615, 2023
6ZN5	SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-06 公開日 2020-07-29 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020

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