5BPC

DNA polymerase beta ternary complex with a templating 5ClC and incoming dATP analog

Summary for 5BPC

• Entry DOI: 10.2210/pdb5bpc/pdb
• Descriptor: DNA polymerase beta, DNA (5'-D(P*GP*TP*CP*GP*G)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... (8 entities in total)
• Functional Keywords: transferase, lyase/dna, ligase-dna complex, ligase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 48434.24

Authors

Freudenthal, B.D.,Wilson, S.H. (deposition date: 2015-05-28, release date: 2015-08-19, Last modification date: 2024-03-06)

• Primary citation: Fedeles, B.I.,Freudenthal, B.D.,Yau, E.,Singh, V.,Chang, S.C.,Li, D.,Delaney, J.C.,Wilson, S.H.,Essigmann, J.M.; Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer.; Proc.Natl.Acad.Sci.USA, 112:E4571-E4580, 2015; PubMed: 26243878; DOI: 10.1073/pnas.1507709112

Experimental method

X-RAY DIFFRACTION (2 Å)