PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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4WYL	Mutant K18E of 3D polymerase from Foot-and-Moth Disease Virus 分子名称: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... 著者 Ferrer-Orta, C, Verdaguer, N, de la Higuera, I, Domingo, E. 登録日 2014-11-17 公開日 2015-05-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. J.Virol., 89, 2015
5T16	Crystal structure of yeast RNase III (Rnt1p) complexed with a non-hydrolyzable RNA substrate analog 分子名称: 1,2-ETHANEDIOL, RNA substrate analog, Ribonuclease 3 著者 Song, H, Ji, X. 登録日 2016-08-18 公開日 2017-02-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.783 Å) 主引用文献 The Functional Cycle of Rnt1p: Five Consecutive Steps of Double-Stranded RNA Processing by a Eukaryotic RNase III. Structure, 25, 2017
2PQF	Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment in complex with an inhibitor 3-Aminobenzoic acid 分子名称: 3-AMINOBENZOIC ACID, CITRIC ACID, Poly [ADP-ribose] polymerase 12 著者 Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hogbom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) 登録日 2007-05-02 公開日 2007-05-15 最終更新日 2015-04-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein. J.Biol.Chem., 290, 2015
2PHZ	Crystal structure of Iron-uptake system-binding protein FeuA from Bacillus subtilis. Northeast Structural Genomics target SR580. 分子名称: Iron-uptake system-binding protein 著者 Benach, J, Neely, H, Seetharaman, J, Chen, C.X, Cunningham, K, Ma, L.-C, Janjua, H, Xiao, R, Baran, M, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2007-04-12 公開日 2007-04-24 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of Iron-uptake system-binding protein FeuA from Bacillus subtilis. To be Published
5T9G	Crystal structure of BuGH2Cwt in complex with Galactoisofagomine 分子名称: 1,2-ETHANEDIOL, D-galacto-isofagomine, Glycoside Hydrolase 著者 Pluvinage, B, Boraston, A.B. 登録日 2016-09-09 公開日 2017-09-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nat Commun, 9, 2018
2PR9	Mu2 adaptin subunit (AP50) of AP2 adaptor (second domain), complexed with GABAA receptor-gamma2 subunit-derived internalization peptide DEEYGYECL 分子名称: AP-2 complex subunit mu-1, GABA(A) receptor subunit gamma-2 peptide 著者 Vahedi-Faridi, A, Haucke, V, Kittler, J.T, Kukhtina, V, Moss, S.J, Saenger, W, Chen, G.-J, Tretter, V, Smith, K, Yan, Z, McAinsh, K, Arancibia-Carcamo, L. 登録日 2007-05-04 公開日 2008-03-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Regulation of synaptic inhibition by phospho-dependent binding of the AP2 complex to a YECL motif in the GABAA receptor gamma2 subunit. Proc.Natl.Acad.Sci.Usa, 105, 2008
6C31	Crystal structure of TetR family protein Rv0078 in complex with DNA 分子名称: DNA (5'-D(*GP*TP*TP*AP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*GP*CP*TP*TP*GP*TP*AP*AP*A)-3'), DNA (5'-D(P*AP*CP*AP*AP*GP*CP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*TP*AP*AP*C)-3'), TetR family transcriptional regulator 著者 Hsu, H.C, Li, H. 登録日 2018-01-09 公開日 2018-07-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Cytokinin Signaling in Mycobacterium tuberculosis. MBio, 9, 2018
2PHH	THE COENZYME ANALOGUE ADENOSINE 5-DIPHOSPHORIBOSE DISPLACES FAD IN THE ACTIVE SITE OF P-HYDROXYBENZOATE HYDROXYLASE. AN X-RAY CRYSTALLOGRAPHIC INVESTIGATION 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID 著者 Van Derlaan, J.M, Drenth, J, Hol, W.G.J. 登録日 1989-06-19 公開日 1990-10-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The coenzyme analogue adenosine 5-diphosphoribose displaces FAD in the active site of p-hydroxybenzoate hydroxylase. An x-ray crystallographic investigation. Biochemistry, 28, 1989
5SY5	Crystal Structure of the Heterodimeric NPAS1-ARNT Complex 分子名称: Aryl hydrocarbon receptor nuclear translocator, Neuronal PAS domain-containing protein 1 著者 Wu, D, Su, X, Potluri, N, Kim, Y, Rastinejad, F. 登録日 2016-08-10 公開日 2016-11-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.201 Å) 主引用文献 NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. Elife, 5, 2016
6BYT	Complex structure of LOR107 mutant (R320) with tetrasaccharide substrate 分子名称: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-3-O-sulfo-alpha-L-rhamnopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-3-O-sulfo-alpha-L-rhamnopyranose, CALCIUM ION, GLYCEROL, ... 著者 Ulaganathan, T.S, Cygler, M. 登録日 2017-12-21 公開日 2018-02-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-function analyses of a PL24 family ulvan lyase reveal key features and suggest its catalytic mechanism. J. Biol. Chem., 293, 2018
2ODN	MSRECA-dATP complex 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Protein recA 著者 Krishna, R, Rajan Prabu, J, Manjunath, G.P, Datta, S, Chandra, N.R, Muniyappa, K, Vijayan, M. 登録日 2006-12-24 公開日 2007-06-19 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Snapshots of RecA protein involving movement of the C-domain and different conformations of the DNA-binding loops: crystallographic and comparative analysis of 11 structures of Mycobacterium smegmatis RecA J.Mol.Biol., 367, 2007
4WMH	Structure of heme oxygenase-2 containing residues 1-288 lacking the membrane spanning region 分子名称: CHLORIDE ION, Heme oxygenase 2 著者 Bianchetti, C.M, Li, Y, Ragsdale, S.W, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) 登録日 2014-10-09 公開日 2014-11-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of heme oxygenase-2 containing residues 1-288 lacking the membrane spanning region To Be Published
5SWL	Crystal Structure of ATPase delta1-79 Spa47 E188A 分子名称: Probable ATP synthase SpaL/MxiB, SULFATE ION 著者 Morales, Y, Johnson, S.J, Burgess, J.L, Burgess, R.A, Dickenson, N.E. 登録日 2016-08-08 公開日 2016-11-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and Biochemical Characterization of Spa47 Provides Mechanistic Insight into Type III Secretion System ATPase Activation and Shigella Virulence Regulation. J. Biol. Chem., 291, 2016
4YEE	beta2 carbohydrate binding module (CBM) of AMP-activated protein kinase (AMPK) in complex with glucosyl-beta-cyclodextrin 分子名称: 5'-AMP-activated protein kinase subunit beta-2, Cyclic alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-[alpha-D-glucopyranose-(1-6)]alpha-D-glucopyranose, GLYCEROL 著者 Mobbs, J, Gorman, M.A, Parker, M.W, Gooley, P.R, Griffin, M. 登録日 2015-02-24 公開日 2015-04-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase. Biochem.J., 468, 2015
6BU3	CTX-M-27 Beta-Lactamase in Complex with a Non-Covalent Tetrazole Inhibitor 分子名称: Beta-lactamase, N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-1H-benzimidazole-4-carboxamide, SULFATE ION 著者 Pemberton, O.A, Chen, Y. 登録日 2017-12-08 公開日 2018-06-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Antibacterial Spectrum of a Tetrazole-Based Reversible Inhibitor of Serine beta-Lactamases. Antimicrob. Agents Chemother., 62, 2018
4YJ5	Crystal structure of PKM2 mutant 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, PYRUVIC ACID, ... 著者 Liu, J.-S, Wu, C.-W, Wang, W.-C. 登録日 2015-03-03 公開日 2016-03-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation Commun Biol, 2, 2019
2OHI	Crystal Structure of coenzyme F420H2 oxidase (FprA), a diiron flavoprotein, reduced state 分子名称: CHLORIDE ION, FE (III) ION, FLAVIN MONONUCLEOTIDE, ... 著者 Seedorf, H, Warkentin, E, Ermler, U. 登録日 2007-01-10 公開日 2007-05-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of coenzyme F420H2 oxidase (FprA), a di-iron flavoprotein from methanogenic Archaea catalyzing the reduction of O2 to H2O. Febs J., 274, 2007
5T4E	Human DPP4 in complex with ligand 19a 分子名称: 2-[(3R)-3-aminopiperidin-1-yl]-3-(but-2-yn-1-yl)-6-[(4-methylquinazolin-2-yl)methyl]-6,7,8,9-tetrahydropyrimido[2,1-b]purin-4(3H)-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G. 登録日 2016-08-29 公開日 2016-10-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Scaffold-hopping from xanthines to tricyclic guanines: A case study of dipeptidyl peptidase 4 (DPP4) inhibitors. Bioorg.Med.Chem., 24, 2016
5V3C	Crystal structure of TGT in complex with 4-(aminomethane)cyclohexane-1-carboxylic acid 分子名称: DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, Queuine tRNA-ribosyltransferase, ... 著者 Hassaan, E, Heine, A, Klebe, G. 登録日 2017-03-07 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.419 Å) 主引用文献 Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies. Chemmedchem, 15, 2020
5UOA	Structure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-Amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(methylamino)methyl]benzonitrile, CHLORIDE ION, ... 著者 Chreifi, G, Li, H, Poulos, T.L. 登録日 2017-01-31 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
2NSB	Structures of and interactions between domains of trigger factor from Themotoga maritima 分子名称: Trigger factor 著者 Martinez-Hackert, E, Hendrickson, W.A. 登録日 2006-11-03 公開日 2007-03-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structures of and interactions between domains of trigger factor from Thermotoga maritima. Acta Crystallogr.,Sect.D, 63, 2007
4YMN	Structure of human DNA polymerase beta complexed with N7BG in the template base paired with incoming non-hydrolyzable CTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA 10-mer (up-primer), DNA 16-mer (template), ... 著者 Lee, S, Koag, M.-C. 登録日 2015-03-06 公開日 2016-03-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.591 Å) 主引用文献 Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication. Biochemistry, 2018
6BX4	The crystal structure of fluoride channel Fluc Ec2 with Monobody S9 分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, FLUORIDE ION, Fluoride ion transporter CrcB, ... 著者 Turman, D.L, Miller, C. 登録日 2017-12-16 公開日 2018-02-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Molecular Interactions between a Fluoride Ion Channel and Synthetic Protein Blockers. Biochemistry, 57, 2018
2OBI	Crystal structure of the Selenocysteine to Cysteine Mutant of human phospholipid hydroperoxide glutathione peroxidase (GPx4) 分子名称: Phospholipid hydroperoxide glutathione peroxidase (GPX4) 著者 Scheerer, P, Krauss, N, Hoehne, W. 登録日 2006-12-19 公開日 2007-09-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural basis for catalytic activity and enzyme polymerization of phospholipid hydroperoxide glutathione peroxidase-4 (GPx4). Biochemistry, 46, 2007
6BYP	Structure of PL24 family Polysaccharide lyase-LOR107 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Ulaganathan, T.S, Cygler, M. 登録日 2017-12-21 公開日 2018-02-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-function analyses of a PL24 family ulvan lyase reveal key features and suggest its catalytic mechanism. J. Biol. Chem., 293, 2018

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