5V3C
Crystal structure of TGT in complex with 4-(aminomethane)cyclohexane-1-carboxylic acid
Summary for 5V3C
Entry DOI | 10.2210/pdb5v3c/pdb |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID, ... (7 entities in total) |
Functional Keywords | tgt, trna, guanine exchange enzyme, transglycosylase, transferase |
Biological source | Zymomonas mobilis |
Total number of polymer chains | 1 |
Total formula weight | 42504.78 |
Authors | Hassaan, E.,Heine, A.,Klebe, G. (deposition date: 2017-03-07, release date: 2018-05-16, Last modification date: 2024-01-17) |
Primary citation | Hassaan, E.,Eriksson, P.O.,Geschwindner, S.,Heine, A.,Klebe, G. Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies. Chemmedchem, 15:324-337, 2020 Cited by PubMed: 31808981DOI: 10.1002/cmdc.201900604 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.419 Å) |
Structure validation
Download full validation report