PDB: 45118 件ウェブページステータス検索Chemie searchBIRD

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8DT9	Crystal Structure of SARS CoV-2 Mpro mutant L141R with Pfizer Intravenous Inhibitor PF-00835231 分子名称: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide, ... 著者 Shaqra, A.M, Schiffer, C.A. 登録日 2022-07-25 公開日 2024-02-07 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Contributions of Hyperactive Mutations in M pro from SARS-CoV-2 to Drug Resistance. Acs Infect Dis., 10, 2024
8F5A	Crystal Structure of KS1 TCR in complex with HLA-B*57:01-TW10 分子名称: ACETATE ION, Beta-2-microglobulin, CHLORIDE ION, ... 著者 Chatzileontiadou, D.S.M, Lobos, C.A, Gras, S. 登録日 2022-11-12 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of KS1 TCR in complex with HLA-B*57:01-TW10 To Be Published
8EN9	TehA native-SAD structure determined at 5 keV with a helium environment 分子名称: CHLORIDE ION, SODIUM ION, Tellurite resistance protein TehA homolog, ... 著者 Karasawa, A, Andi, B, Ruchs, M.R, Shi, W, McSweeney, S, Hendrickson, W.A, Liu, Q. 登録日 2022-09-29 公開日 2022-11-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Multi-crystal native-SAD phasing at 5 keV with a helium environment. Iucrj, 9, 2022
6ORJ	Central spike of phiKZ phage tail 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, PHIKZ164, ... 著者 Leiman, P.G, Browning, C, Shneider, M.M. 登録日 2019-04-30 公開日 2019-06-19 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Central spike of phiKZ phage tail To Be Published
6LEH	Crystal structure of Autotaxin in complex with an inhibitor 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Nishimasu, H, Osamu, N. 登録日 2019-11-25 公開日 2020-03-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Identification of PotentIn VivoAutotaxin Inhibitors that Bind to Both Hydrophobic Pockets and Channels in the Catalytic Domain. J.Med.Chem., 63, 2020
6LP8	Crystal structure of human DHODH in complex with inhibitor 1243 分子名称: 3-[4-[3-(dimethylamino)phenyl]-3,5-bis(fluoranyl)phenyl]benzo[f]benzotriazole-4,9-dione, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... 著者 Chen, Q, Yu, Y. 登録日 2020-01-09 公開日 2020-09-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Bifunctional Naphtho[2,3- d ][1,2,3]triazole-4,9-dione Compounds Exhibit Antitumor Effects In Vitro and In Vivo by Inhibiting Dihydroorotate Dehydrogenase and Inducing Reactive Oxygen Species Production. J.Med.Chem., 63, 2020
5NJA	E. coli Microcin-processing metalloprotease TldD/E with angiotensin analogue bound 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HIS-PRO-PHE, ... 著者 Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K. 登録日 2017-03-28 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure, 25, 2017
5NEP	The structure of the G. violaceus guanidine II riboswitch P1 stem-loop with methylguanidine 分子名称: 1-METHYLGUANIDINE, RNA (5'-R(*GP*GP*UP*GP*GP*GP*GP*AP*CP*GP*AP*CP*CP*CP*CP*AP*(CBV)P*C)-3'), SODIUM ION, ... 著者 Huang, L, Wang, J, Lilley, D.M.J. 登録日 2017-03-11 公開日 2017-05-31 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The Structure of the Guanidine-II Riboswitch. Cell Chem Biol, 24, 2017
5M4J	Crystal Structure of Wild-Type Human Prolidase with GlyPro ligand 分子名称: GLYCEROL, GLYCINE, PROLINE, ... 著者 Wilk, P, Weiss, M.S, Mueller, U, Dobbek, H. 登録日 2016-10-18 公開日 2017-07-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Substrate specificity and reaction mechanism of human prolidase. FEBS J., 284, 2017
6USA	Crystal structure of tryptophan synthase from M. tuberculosis - aminoacrylate- and GSK1-bound form 分子名称: (3R,4R)-4-[4-(2-Chlorophenyl)piperazin-1-yl]-1,1-dioxothiolan-3-ol, 1,2-ETHANEDIOL, 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, ... 著者 Chang, C, Michalska, K, Maltseva, N.I, Jedrzejczak, R, McCarren, P, Nag, P.P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-10-25 公開日 2020-09-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.406 Å) 主引用文献 Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase. Protein Sci., 29, 2020
6OXN	2.6 Angstrom structure of W45F/H46S Glyoxylate/Hydroxypyruvate reductase A from Escherichia Coli in complex with glyoxylate and NADP 分子名称: GLYCEROL, GLYOXYLIC ACID, Glyoxylate/hydroxypyruvate reductase A, ... 著者 Vuksanovic, N, Silvaggi, N.R. 登録日 2019-05-13 公開日 2020-05-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 2.1 Angstrom structure of wild type Glyoxylate/Hydroxypyruvate reductase A from Escherichia Coli in complex with glyoxylate and NADP To Be Published
5LR4	RNA duplex has central consecutive GA pairs flanked by G-U basepairs with a methyl group on the adenine N6 分子名称: RNA (5'-R(*GP*(CBV)P*CP*GP*GP*(6MZ)P*UP*GP*GP*C)-3'), SODIUM ION 著者 Huang, L, Lilley, D.M.J. 登録日 2016-08-18 公開日 2017-06-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Control of box C/D snoRNP assembly by N(6)-methylation of adenine. EMBO Rep., 18, 2017
5LHL	Crystal Structure of Two-Domain Laccase from Streptomyces griseoflavus 分子名称: CHLORIDE ION, COPPER (II) ION, OXYGEN MOLECULE, ... 著者 Gabdulkhakov, A.G. 登録日 2016-07-12 公開日 2017-08-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Two-Domain Laccase from Streptomyces griseoflavus To Be Published
3VSB	SUBTILISIN CARLSBERG D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX 分子名称: SODIUM ION, SUBTILISIN CARLSBERG, TYPE VIII 著者 Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. 登録日 1997-09-25 公開日 1998-03-25 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. Biochemistry, 37, 1998
4XOJ	Structure of bovine trypsin in complex with analogues of sunflower inhibitor 1 (SFTI-1) 分子名称: 1,2-ETHANEDIOL, AMMONIUM ION, CALCIUM ION, ... 著者 Golik, P, Malicki, S, Grudnik, P, Karna, N, Debowski, D, Legowska, A, Wladyka, B, Gitlin, A, Brzozowski, K, Dubin, G, Rolka, K. 登録日 2015-01-16 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (0.91 Å) 主引用文献 Investigation of Serine-Proteinase-Catalyzed Peptide Splicing in Analogues of Sunflower Trypsin Inhibitor 1 (SFTI-1). Chembiochem, 16, 2015
2IZE	APOSTREPTAVIDIN PH 3.08 I222 COMPLEX 分子名称: AMMONIUM ION, CHLORIDE ION, FORMIC ACID, ... 著者 Katz, B.A. 登録日 1997-08-13 公開日 1998-09-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
6PBK	Archaellum periplasmic stator protein complex FlaF and FlaG from Sulfolobus acidocaldarius 分子名称: 1,2-ETHANEDIOL, Conserved flagellar protein F, DI(HYDROXYETHYL)ETHER, ... 著者 Tsai, C.-L, Tainer, J.A. 登録日 2019-06-14 公開日 2019-11-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.805 Å) 主引用文献 The structure of the periplasmic FlaG-FlaF complex and its essential role for archaellar swimming motility. Nat Microbiol, 5, 2020
6MEC	Structure of a group II intron retroelement after DNA integration 分子名称: MAGNESIUM ION, Maturase reverse transcriptase, SODIUM ION, ... 著者 Haack, D, Yan, X, Zhang, C, Hingey, J, Lyumkis, D, Baker, T.S, Toor, N. 登録日 2018-09-06 公開日 2019-08-14 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM Structures of a Group II Intron Reverse Splicing into DNA. Cell, 178, 2019
5MLO	Crystal structure of human PCNA in complex with ZRANB3 PIP box peptide 分子名称: Proliferating cell nuclear antigen, SODIUM ION, ZRANB3 PIP box peptide 著者 Ariza, A. 登録日 2016-12-07 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structural insights into the function of ZRANB3 in replication stress response. Nat Commun, 8, 2017
4XD0	X-ray structure of the N-formyltransferase QdtF from Providencia alcalifaciens 分子名称: (3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate, CHLORIDE ION, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ... 著者 Thoden, J.B, Woodford, C.R, Holden, H.M. 登録日 2014-12-18 公開日 2015-01-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 New Role for the Ankyrin Repeat Revealed by a Study of the N-Formyltransferase from Providencia alcalifaciens. Biochemistry, 54, 2015
6VH9	FphF, Staphylococcus aureus fluorophosphonate-binding serine hydrolases F, apo form 分子名称: Esterase family protein, SODIUM ION 著者 Fellner, M, Jamieson, S.A, Brewster, J.L, Mace, P.D. 登録日 2020-01-09 公開日 2020-09-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of Staphylococcus aureus . Acs Infect Dis., 6, 2020
5MXE	Photorhabdus asymbiotica lectin (PHL) in free form 分子名称: CHLORIDE ION, Photorhabdus asymbiotica lectin PHL, SODIUM ION 著者 Jancarikova, G, Houser, J, Demo, G, Wimmerova, M. 登録日 2017-01-23 公開日 2017-08-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity. PLoS Pathog., 13, 2017
7D0Z	NMR solution structures of the DNA minidumbbell formed by two CCTG repeats at pH 5 分子名称: DNA (5'-D(*(DCZ)P*CP*TP*GP*CP*CP*TP*G)-3'), SODIUM ION 著者 Guo, P, Lam, S.L. 登録日 2020-09-12 公開日 2021-02-03 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 5-Methylcytosine Substantially Enhances the Thermal Stability of DNA Minidumbbells. Chemistry, 27, 2021
6UOM	Y271G DNA polymerase beta ternary complex with templating adenine and incoming r8-oxo-GTP 分子名称: 1,2-ETHANEDIOL, 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Smith, M.R, Freudenthal, B.D. 登録日 2019-10-15 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase beta. J.Biol.Chem., 295, 2020
5M85	Three-dimensional structure of the intermediate state of GAF3 from Slr1393 of Synechocystis sp. PCC6803 分子名称: (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHYCOCYANOBILIN, ... 著者 Xu, X.-L, Zhao, K.-H, Gaertner, W, Hoeppner, A. 登録日 2016-10-28 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural elements regulating the photochromicity in a cyanobacteriochrome Proc.Natl.Acad.Sci.USA, 2020

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