PDB: 48062 件ウェブページステータス検索Chemie searchBIRD

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1FDV	HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 MUTANT H221L COMPLEXED WITH NAD+ 分子名称: 17-BETA-HYDROXYSTEROID DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION 著者 Mazza, C, Breton, R, Housset, D, Fontecilla-Camps, J.-C. 登録日 1998-01-15 公開日 1998-05-27 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Unusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenase. J.Biol.Chem., 273, 1998
7JGI	NMR structure of the cNTnC-cTnI chimera bound to A7 分子名称: 7-{[(5-chloronaphthalen-1-yl)sulfonyl]amino}heptanoic acid, CALCIUM ION, Troponin C, ... 著者 Cai, F, Robertson, I.M, Kampourakis, T, Klein, B.A, Sykes, B.D. 登録日 2020-07-19 公開日 2020-09-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The Role of Electrostatics in the Mechanism of Cardiac Thin Filament Based Sensitizers. Acs Chem.Biol., 15, 2020
7GSB	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000438a 分子名称: 1-(4-benzylpiperidin-1-yl)-2-methylpropan-1-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 著者 Mehlman, T, Ginn, H.M, Keedy, D.A. 登録日 2024-01-03 公開日 2024-01-24 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GLP	Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with ADA-UCB-6c2cb422-1 (Mpro-P2005) 分子名称: 2-(3-chlorophenyl)-N-(isoquinolin-4-yl)acetamide, 3C-like proteinase, CHLORIDE ION, ... 著者 Fearon, D, Aimon, A, Aschenbrenner, J.C, Balcomb, B.H, Bertram, F.K.R, Brandao-Neto, J, Dias, A, Douangamath, A, Dunnett, L, Godoy, A.S, Gorrie-Stone, T.J, Koekemoer, L, Krojer, T, Lithgo, R.M, Lukacik, P, Marples, P.G, Mikolajek, H, Nelson, E, Owen, C.D, Powell, A.J, Rangel, V.L, Skyner, R, Strain-Damerell, C.M, Thompson, W, Tomlinson, C.W.E, Wild, C, Walsh, M.A, von Delft, F. 登録日 2023-08-11 公開日 2023-11-08 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.917 Å) 主引用文献 Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Science, 382, 2023
1MJM	METHIONINE APOREPRESSOR MUTANT (Q44K) COMPLEXED TO HALF OF THE CONSENSUS OPERATOR SEQUENCE 分子名称: HALF CONSENSUS DNA OPERATOR DUPLEX, METHIONINE REPRESSOR 著者 Garvie, C.W, Phillips, S.E.V. 登録日 1998-01-30 公開日 1999-08-02 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Direct and indirect readout in mutant Met repressor-operator complexes. Structure Fold.Des., 8, 2000
1FGK	CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF FIBROBLAST GROWTH FACTOR RECEPTOR 1 分子名称: FGF RECEPTOR 1 著者 Mohammadi, M, Schlessinger, J, Hubbard, S.R. 登録日 1997-02-08 公開日 1997-07-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism. Cell(Cambridge,Mass.), 86, 1996
7GHM	Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with ERI-UCB-ce40166b-17 (Mpro-P0008) 分子名称: 3C-like proteinase, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Fearon, D, Aimon, A, Aschenbrenner, J.C, Balcomb, B.H, Bertram, F.K.R, Brandao-Neto, J, Dias, A, Douangamath, A, Dunnett, L, Godoy, A.S, Gorrie-Stone, T.J, Koekemoer, L, Krojer, T, Lithgo, R.M, Lukacik, P, Marples, P.G, Mikolajek, H, Nelson, E, Owen, C.D, Powell, A.J, Rangel, V.L, Skyner, R, Strain-Damerell, C.M, Thompson, W, Tomlinson, C.W.E, Wild, C, Walsh, M.A, von Delft, F. 登録日 2023-08-11 公開日 2023-11-08 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Science, 382, 2023
6CUA	Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable GTP and MANGANESE 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(CGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-03-24 公開日 2019-03-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable GTP and MANGANESE To Be Published
6CV6	Crystal structure of 3-dehydroquinate dehydratase, type II, from Burkholderia phymatum STM815 分子名称: 3-dehydroquinate dehydratase, CHLORIDE ION, D(-)-TARTARIC ACID, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-03-27 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of 3-dehydroquinate dehydratase, type II, from Burkholderia phymatum STM815 to be published
6CWX	Crystal structure of human ribonuclease P/MRP proteins Rpp20/Rpp25 分子名称: FORMIC ACID, Ribonuclease P protein subunit p20, Ribonuclease P protein subunit p25, ... 著者 Chan, C.W, Kiesel, B.R, Mondragon, A. 登録日 2018-03-31 公開日 2018-04-18 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Human Rpp20/Rpp25 Reveals Quaternary Level Adaptation of the Alba Scaffold as Structural Basis for Single-stranded RNA Binding. J. Mol. Biol., 430, 2018
1MPH	PLECKSTRIN HOMOLOGY DOMAIN FROM MOUSE BETA-SPECTRIN, NMR, 50 STRUCTURES 分子名称: BETA SPECTRIN 著者 Nilges, M, Macias, M.J, O'Donoghue, S.I, Oschkinat, H. 登録日 1997-04-23 公開日 1997-06-16 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from beta-spectrin. J.Mol.Biol., 269, 1997
1FOH	PHENOL HYDROXYLASE FROM TRICHOSPORON CUTANEUM 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, PHENOL, PHENOL HYDROXYLASE 著者 Enroth, C, Neujahr, H, Schneider, G, Lindqvist, Y. 登録日 1998-03-26 公開日 1998-06-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The crystal structure of phenol hydroxylase in complex with FAD and phenol provides evidence for a concerted conformational change in the enzyme and its cofactor during catalysis. Structure, 6, 1998
6D0N	Crystal structure of a CLC-type fluoride/proton antiporter, V319G mutant 分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, CLC-type fluoride/proton antiporter, DECYL-BETA-D-MALTOPYRANOSIDE, ... 著者 Last, N.B, Stockbridge, R.B, Wilson, A.E, Shane, T, Kolmakova-Partensky, L, Koide, A, Koide, S, Miller, C. 登録日 2018-04-10 公開日 2018-07-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 A CLC-type F-/H+antiporter in ion-swapped conformations. Nat. Struct. Mol. Biol., 25, 2018
1MHY	METHANE MONOOXYGENASE HYDROXYLASE 分子名称: FE (III) ION, METHANE MONOOXYGENASE HYDROXYLASE 著者 Elango, N, Radhakrishnan, R, Froland, W.A, Waller, B.J, Earhart, C.A, Lipscomb, J.D, Ohlendorf, D.H. 登録日 1996-10-21 公開日 1997-05-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the hydroxylase component of methane monooxygenase from Methylosinus trichosporium OB3b Protein Sci., 6, 1997
1FO0	MURINE ALLOREACTIVE SCFV TCR-PEPTIDE-MHC CLASS I MOLECULE COMPLEX 分子名称: NATURALLY PROCESSED OCTAPEPTIDE PBM1, PROTEIN (ALLOGENEIC H-2KB MHC CLASS I MOLECULE), PROTEIN (BETA-2 MICROGLOBULIN), ... 著者 Reiser, J.B, Darnault, C, Guimezanes, A, Gregoire, C, Mosser, T, Schmitt-Verhulst, A.-M, Fontecilla-Camps, J.C, Malissen, B, Housset, D, Mazza, G. 登録日 2000-08-24 公開日 2000-10-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of a T cell receptor bound to an allogeneic MHC molecule. Nat.Immunol., 1, 2000
6CY1	Crystal structure of Signal recognition particle receptor FtsY from Elizabethkingia anophelis 分子名称: 1,2-ETHANEDIOL, SULFATE ION, Signal recognition particle receptor FtsY 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-04-04 公開日 2018-05-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Signal recognition particle receptor FtsY from Elizabethkingia anophelis to be published
1M0D	Crystal Structure of Bacteriophage T7 Endonuclease I with a Wild-Type Active Site and Bound Manganese Ions 分子名称: Endodeoxyribonuclease I, MANGANESE (II) ION, SULFATE ION 著者 Hadden, J.M, Declais, A.C, Phillips, S.E, Lilley, D.M. 登録日 2002-06-12 公開日 2002-07-10 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Metal ions bound at the active site of the junction-resolving enzyme T7 endonuclease I. EMBO J., 21, 2002
6COX	CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2) COMPLEXED WITH A SELECTIVE INHIBITOR, SC-558 IN I222 SPACE GROUP 分子名称: 1-PHENYLSULFONAMIDE-3-TRIFLUOROMETHYL-5-PARABROMOPHENYLPYRAZOLE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLOOXYGENASE-2, ... 著者 Kurumbail, R, Stallings, W. 登録日 1996-12-18 公開日 1997-12-24 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature, 384, 1996
1MLW	Crystal structure of human tryptophan hydroxylase with bound 7,8-dihydro-L-biopterin cofactor and Fe(III) 分子名称: 7,8-DIHYDROBIOPTERIN, FE (III) ION, Tryptophan 5-monooxygenase 著者 Wang, L, Erlandsen, H, Haavik, J, Knappskog, P.M, Stevens, R.C. 登録日 2002-08-31 公開日 2002-12-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin Biochemistry, 41, 2002
1M4L	STRUCTURE OF NATIVE CARBOXYPEPTIDASE A AT 1.25 RESOLUTION 分子名称: CARBOXYPEPTIDASE A, ZINC ION 著者 Kilshtain-Vardi, A, Glick, M, Greenblatt, H.M, Goldblum, A, Shoham, G. 登録日 2002-07-03 公開日 2003-01-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Refined structure of bovine carboxypeptidase A at 1.25 A resolution. Acta Crystallogr.,Sect.D, 59, 2003
1M4Z	Crystal structure of the N-terminal BAH domain of Orc1p 分子名称: MANGANESE (II) ION, ORIGIN RECOGNITION COMPLEX SUBUNIT 1 著者 Zhang, Z, Hayashi, M.K, Merkel, O, Stillman, B, Xu, R.-M. 登録日 2002-07-05 公開日 2002-09-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and function of the BAH-containing domain of Orc1p in epigenetic silencing. EMBO J., 21, 2002
7GNL	Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with NIR-WEI-dcc3321b-1 (Mpro-P2757) 分子名称: (4S)-6-chloro-2-{2-[4-(4-ethylpiperazin-1-yl)anilino]-2-oxoethyl}-N-(isoquinolin-4-yl)-1,2,3,4-tetrahydroisoquinoline-4-carboxamide, 3C-like proteinase, CHLORIDE ION, ... 著者 Fearon, D, Aimon, A, Aschenbrenner, J.C, Balcomb, B.H, Bertram, F.K.R, Brandao-Neto, J, Dias, A, Douangamath, A, Dunnett, L, Godoy, A.S, Gorrie-Stone, T.J, Koekemoer, L, Krojer, T, Lithgo, R.M, Lukacik, P, Marples, P.G, Mikolajek, H, Nelson, E, Owen, C.D, Powell, A.J, Rangel, V.L, Skyner, R, Strain-Damerell, C.M, Thompson, W, Tomlinson, C.W.E, Wild, C, Walsh, M.A, von Delft, F. 登録日 2023-08-11 公開日 2023-11-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.681 Å) 主引用文献 Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Science, 382, 2023
6CFN	Crystal Structure of the DNA-free Glucocorticoid Receptor DNA Binding Domain 分子名称: Glucocorticoid receptor, ZINC ION 著者 Frank, F, Okafor, C.D, Ortlund, E.A. 登録日 2018-02-15 公開日 2018-09-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The first crystal structure of a DNA-free nuclear receptor DNA binding domain sheds light on DNA-driven allostery in the glucocorticoid receptor. Sci Rep, 8, 2018
7JN4	Rubisco in the apo state 分子名称: Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain 2, chloroplastic 著者 Matthies, D, Jonikas, M.C, He, S. 登録日 2020-08-03 公開日 2020-11-18 最終更新日 2020-12-23 実験手法 ELECTRON MICROSCOPY (2.68 Å) 主引用文献 The structural basis of Rubisco phase separation in the pyrenoid. Nat.Plants, 6, 2020
1MPP	X-RAY ANALYSES OF ASPARTIC PROTEINASES. V. STRUCTURE AND REFINEMENT AT 2.0 ANGSTROMS RESOLUTION OF THE ASPARTIC PROTEINASE FROM MUCOR PUSILLUS 分子名称: PEPSIN, SULFATE ION 著者 Newman, M, Watson, F, Roychowdhury, P, Jones, H, Badasso, M, Cleasby, A, Wood, S.P, Tickle, I.J, Blundell, T.L. 登録日 1992-02-19 公開日 1993-10-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray analyses of aspartic proteinases. V. Structure and refinement at 2.0 A resolution of the aspartic proteinase from Mucor pusillus. J.Mol.Biol., 230, 1993

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