1MLW
Crystal structure of human tryptophan hydroxylase with bound 7,8-dihydro-L-biopterin cofactor and Fe(III)
Summary for 1MLW
Entry DOI | 10.2210/pdb1mlw/pdb |
Descriptor | Tryptophan 5-monooxygenase, FE (III) ION, 7,8-DIHYDROBIOPTERIN, ... (4 entities in total) |
Functional Keywords | aromatic amino acid hydroxylase catalytic domain fold, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 34936.60 |
Authors | Wang, L.,Erlandsen, H.,Haavik, J.,Knappskog, P.M.,Stevens, R.C. (deposition date: 2002-08-31, release date: 2002-12-18, Last modification date: 2024-02-14) |
Primary citation | Wang, L.,Erlandsen, H.,Haavik, J.,Knappskog, P.M.,Stevens, R.C. Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin Biochemistry, 41:12569-12574, 2002 Cited by PubMed: 12379098DOI: 10.1021/bi026561f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.71 Å) |
Structure validation
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