3TVN
 
 | | Human Carbonic Anhydrase II Proton Transfer Mutant | | 分子名称: | Carbonic anhydrase 2, ZINC ION | | 著者 | Mikulski, R.L, West, D.M, Sippel, K.H, Avvaru, B.S, Chingkuang, T, McKenna, R. | | 登録日 | 2011-09-20 | | 公開日 | 2012-08-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.497 Å) | | 主引用文献 | Water Networks in Fast Proton Transfer during Catalysis by Human Carbonic Anhydrase II.
Biochemistry, 52, 2013
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3HJY
 | | Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA | | 分子名称: | 5'-R(*GP*GP*AP*GP*CP*GP*UP*GP*CP*GP*GP*UP*UP*U)-3', 5'-R(*GP*GP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*CP*CP*GP*CP*GP*GP*CP*GP*C)-3', RNA (25-MER), ... | | 著者 | Liang, B, Zhou, J, Kahen, E, Terns, R.M, Terns, M.P, Li, H. | | 登録日 | 2009-05-22 | | 公開日 | 2009-06-23 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA
Nat.Struct.Mol.Biol., 16, 2009
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6U36
 | | PCSK9 in complex with a Fab and compound 14 | | 分子名称: | 2-fluoro-4-{[(1R)-6-(2-{4-[1-(4-methoxyphenyl)-5-methyl-6-oxo-1,6-dihydropyridazin-3-yl]-1H-1,2,3-triazol-1-yl}ethoxy)-1-methyl-1-{2-oxo-2-[(1,3-thiazol-2-yl)amino]ethyl}-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}benzoic acid, Fab Heavy Chain, Fab Light Chain, ... | | 著者 | Lu, J, Soisson, S. | | 登録日 | 2019-08-21 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.
Cell Chem Biol, 27, 2020
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4ZF7
 | | Crystal structure of ferret interleukin-2 | | 分子名称: | DI(HYDROXYETHYL)ETHER, Interleukin 2, PENTAETHYLENE GLYCOL, ... | | 著者 | Ren, B, Newman, J, McKinstry, W.J, Adams, T.E. | | 登録日 | 2015-04-21 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.893 Å) | | 主引用文献 | Structural and functional characterisation of ferret interleukin-2.
Dev.Comp.Immunol., 55, 2015
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8DNO
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6IQE
 | | Human prohibitin 2 | | 分子名称: | Prohibitin-2 | | 著者 | Hirano, Y, Koshiba, T, Tamada, T. | | 登録日 | 2018-11-07 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | Structural Basis of Mitochondrial Scaffolds by Prohibitin Complexes: Insight into a Role of the Coiled-Coil Region.
Iscience, 19, 2019
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1RTX
 | | Crystal Structure of Synechocystis Hemoglobin with a Covalent Heme Linkage | | 分子名称: | CADMIUM ION, Cyanoglobin, POTASSIUM ION, ... | | 著者 | Hoy, J.A, Kundu, S, Trent, J.T, Ramaswamy, S, Hargrove, M.S. | | 登録日 | 2003-12-10 | | 公開日 | 2004-04-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structure of synechocystis hemoglobin with a covalent heme linkage.
J.Biol.Chem., 279, 2004
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3HJW
 | | Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA | | 分子名称: | 5'-R(*GP*AP*GP*CP*GP*(FHU)P*GP*CP*GP*GP*UP*UP*U)-3', 50S ribosomal protein L7Ae, POTASSIUM ION, ... | | 著者 | Liang, B, Zhou, J, Kahen, E, Terns, R.M, Terns, M.P, Li, H. | | 登録日 | 2009-05-22 | | 公開日 | 2009-06-23 | | 最終更新日 | 2024-11-27 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA
Nat.Struct.Mol.Biol., 16, 2009
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8DNS
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1RE0
 | | Structure of ARF1-GDP bound to Sec7 domain complexed with Brefeldin A | | 分子名称: | 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE, ADP-ribosylation factor 1, ARF guanine-nucleotide exchange factor 1, ... | | 著者 | Goldberg, J, Mossessova, E. | | 登録日 | 2003-11-06 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of ARF1*Sec7 complexed with Brefeldin A and its implications for the guanine nucleotide exchange mechanism.
Mol.Cell, 12, 2003
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3U49
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4IAF
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2DQZ
 | | Crystal structure of human carboxylesterase in complex with homatropine, coenzyme A, and palmitate | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COENZYME A, FLUORIDE ION, ... | | 著者 | Bencharit, S, Redinbo, M.R. | | 登録日 | 2006-06-02 | | 公開日 | 2006-08-29 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
J.Mol.Biol., 363, 2006
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2DUX
 | | Crystal structure of human Aldose Reductase complexed with zopolrestat after 3 days soaking (3days_soaked_1) | | 分子名称: | 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Steuber, H, Heine, A, Klebe, G. | | 登録日 | 2006-07-27 | | 公開日 | 2006-10-03 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions
J.Mol.Biol., 363, 2006
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3KWO
 | | Crystal Structure of Putative Bacterioferritin from Campylobacter jejuni | | 分子名称: | 1,4-BUTANEDIOL, ACETIC ACID, GLYCEROL, ... | | 著者 | Kim, Y, Gu, M, Papazisi, L, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-12-01 | | 公開日 | 2010-01-19 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.985 Å) | | 主引用文献 | Crystal Structure of Putative Bacterioferritin from Campylobacter jejuni
To be Published
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2A8X
 | | Crystal Structure of Lipoamide Dehydrogenase from Mycobacterium tuberculosis | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Rajashankar, K.R, Bryk, R, Kniewel, R, Buglino, J.A, Nathan, C.F, Lima, C.D. | | 登録日 | 2005-07-10 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis
J.Biol.Chem., 280, 2005
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4ZK0
 | | Psoriasis pathogenesis - Pso p27 constitute a compact structure forming large aggregates. High pH structure | | 分子名称: | Serpin B4, ZINC ION | | 著者 | Helland, R, Lysvand, H, Slupphaug, G, Iversen, O.J. | | 登録日 | 2015-04-29 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Psoriasis pathogenesis - Pso p27 constitutes a compact structure forming large aggregates.
Biochem Biophys Rep, 2, 2015
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2DWQ
 | | Thermus thermophilus YchF GTP-binding protein | | 分子名称: | GTP-binding protein | | 著者 | Kukimoto-Niino, M, Murayama, K, Shorouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-08-16 | | 公開日 | 2007-02-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Thermus thermophilus YchF GTP-binding protein
To be Published
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3KOO
 | | Crystal Structure of soluble epoxide Hydrolase | | 分子名称: | Epoxide hydrolase 2, N-(2,4-dichlorobenzyl)-4-(pyrimidin-2-yloxy)piperidine-1-carboxamide | | 著者 | Farrow, N.A. | | 登録日 | 2009-11-13 | | 公開日 | 2010-04-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.791 Å) | | 主引用文献 | Optimization of piperidyl-ureas as inhibitors of soluble epoxide hydrolase.
Bioorg.Med.Chem.Lett., 20, 2010
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6IPP
 | | Non-native ferritin 8-mer mutant-C90A/C102A/C130A/D144C | | 分子名称: | FE (III) ION, Ferritin heavy chain | | 著者 | Zang, J, Chen, H, Zhou, K, Zhao, G. | | 登録日 | 2018-11-03 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.699 Å) | | 主引用文献 | Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages.
Nat Commun, 10, 2019
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3NTY
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4EBW
 | | Structure of Focal Adhesion Kinase catalytic domain in complex with novel allosteric inhibitor | | 分子名称: | 1-ethyl-8-(4-ethylphenyl)-5-methyl-1,5-dihydropyrazolo[4,3-c][2,1]benzothiazine 4,4-dioxide, Focal adhesion kinase 1 | | 著者 | Iwatani, M, Iwata, H, Okabe, A, Skene, R.J, Tomita, N, Hayashi, Y, Aramaki, Y, Hosfield, D.J, Hori, A, Baba, A, Miki, H. | | 登録日 | 2012-03-25 | | 公開日 | 2012-07-25 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Discovery and characterization of novel allosteric FAK inhibitors.
Eur.J.Med.Chem., 61, 2013
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1R3U
 | | Crystal Structure of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis | | 分子名称: | ACETATE ION, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION | | 著者 | Chen, Q, Liang, Y.H, Gu, X.C, Luo, M, Su, X.D. | | 登録日 | 2003-10-03 | | 公開日 | 2004-10-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis
To be published
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6R4N
 | | Crystal structure of S. cerevisia Niemann-Pick type C protein NPC2 with ergosterol bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ERGOSTEROL, ... | | 著者 | Winkler, M.B.L, Kidmose, R.T, Pedersen, B.P. | | 登録日 | 2019-03-22 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Insight into Eukaryotic Sterol Transport through Niemann-Pick Type C Proteins.
Cell, 179, 2019
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6IRL
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