3KOO

Crystal Structure of soluble epoxide Hydrolase

Summary for 3KOO

Entry DOI	10.2210/pdb3koo/pdb
Descriptor	Epoxide hydrolase 2, N-(2,4-dichlorobenzyl)-4-(pyrimidin-2-yloxy)piperidine-1-carboxamide (3 entities in total)
Functional Keywords	hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P34913
Total number of polymer chains	1
Total formula weight	63066.87
Authors	Farrow, N.A. (deposition date: 2009-11-13, release date: 2010-04-28, Last modification date: 2024-02-21)
Primary citation	Eldrup, A.B.,Soleymanzadeh, F.,Farrow, N.A.,Kukulka, A.,De Lombaert, S. Optimization of piperidyl-ureas as inhibitors of soluble epoxide hydrolase. Bioorg.Med.Chem.Lett., 20:571-575, 2010 Cited by PubMed: 19969453 DOI: 10.1016/j.bmcl.2009.11.091 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.791 Å)

Structure validation