2NQJ
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![BU of 2nqj by Molmil](/molmil-images/mine/2nqj) | Crystal structure of Escherichia coli endonuclease IV (Endo IV) E261Q mutant bound to damaged DNA | 分子名称: | 5'-D(*CP*GP*TP*CP*GP*TP*CP*GP*GP*GP*GP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*CP*CP*(3DR)P*CP*GP*AP*CP*GP*AP*CP*G)-3', Endonuclease 4, ... | 著者 | Garcin-Hosfield, E.D, Hosfield, D.J, Tainer, J.A. | 登録日 | 2006-10-31 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | DNA apurinic-apyrimidinic site binding and excision by endonuclease IV. Nat.Struct.Mol.Biol., 15, 2008
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3K1M
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![BU of 3k1m by Molmil](/molmil-images/mine/3k1m) | Crystal Structure of full-length BenM, R156H mutant | 分子名称: | CHLORIDE ION, GLYCEROL, HTH-type transcriptional regulator benM, ... | 著者 | Ruangprasert, A, Momany, C, Neidle, E.L, Craven, S.H. | 登録日 | 2009-09-28 | 公開日 | 2010-09-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structure of Full-length BenM To be Published
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1RAA
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![BU of 1raa by Molmil](/molmil-images/mine/1raa) | CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | 分子名称: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | 著者 | Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. | 登録日 | 1992-08-14 | 公開日 | 1994-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
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3K2I
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![BU of 3k2i by Molmil](/molmil-images/mine/3k2i) | Human Acyl-coenzyme A thioesterase 4 | 分子名称: | Acyl-coenzyme A thioesterase 4, CHLORIDE ION, NICKEL (II) ION | 著者 | Siponen, M.I, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kraulis, P, Kotenyova, T, Kotzsch, A, Markova, N, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | 登録日 | 2009-09-30 | 公開日 | 2009-10-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Human Acyl-coenzyme A thioesterase 4 To be Published
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4GWN
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![BU of 4gwn by Molmil](/molmil-images/mine/4gwn) | Crystal structure of human mature meprin beta | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Arolas, J.L, Broder, C, Jefferson, T, Guevara, T, Sterchi, E.E, Bode, W, Stocker, W, Becker-Pauly, C, Gomis-Ruth, F.X. | 登録日 | 2012-09-03 | 公開日 | 2012-09-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane Proc.Natl.Acad.Sci.USA, 109, 2012
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6FMX
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![BU of 6fmx by Molmil](/molmil-images/mine/6fmx) | IMISX-EP of W-PgpB | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Phosphatidylglycerophosphatase B, TUNGSTATE(VI)ION | 著者 | Huang, C.-Y, Olieric, V, Howe, N, Warshamanage, R, Weinert, T, Panepucci, E, Vogeley, L, Basu, S, Diederichs, K, Caffrey, M, Wang, M. | 登録日 | 2018-02-02 | 公開日 | 2018-09-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | In situ serial crystallography for rapid de novo membrane protein structure determination. Commun Biol, 1, 2018
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4LCJ
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![BU of 4lcj by Molmil](/molmil-images/mine/4lcj) | CtBP2 in complex with substrate MTOB | 分子名称: | 4-(METHYLSULFANYL)-2-OXOBUTANOIC ACID, C-terminal-binding protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Hilbert, B.J, Schiffer, C.A, Royer Jr, W.E. | 登録日 | 2013-06-21 | 公開日 | 2014-03-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design. Febs Lett., 588, 2014
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6IED
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![BU of 6ied by Molmil](/molmil-images/mine/6ied) | Crystal structure of heme A synthase from Bacillus subtilis | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, COPPER (II) ION, Heme A synthase, ... | 著者 | Niwa, S, Takeda, K, Kosugi, M, Tsutsumi, E, Miki, K. | 登録日 | 2018-09-13 | 公開日 | 2018-11-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of heme A synthase fromBacillus subtilis. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1JX1
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![BU of 1jx1 by Molmil](/molmil-images/mine/1jx1) | Chalcone Isomerase--T48A mutant | 分子名称: | 7-HYDROXY-2-(4-HYDROXY-PHENYL)-CHROMAN-4-ONE, CHALCONE--FLAVONONE ISOMERASE 1, SULFATE ION | 著者 | Jez, J.M, Bowman, M.E, Noel, J.P. | 登録日 | 2001-09-05 | 公開日 | 2002-07-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Role of Hydrogen Bonds in the Reaction Mechanism of Chalcone Isomerase Biochemistry, 41, 2002
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2NLA
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![BU of 2nla by Molmil](/molmil-images/mine/2nla) | Crystal structure of the Mcl-1:mNoxaB BH3 complex | 分子名称: | FUSION PROTEIN CONSISTING OF Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, Phorbol-12-myristate-13-acetate-induced protein 1 | 著者 | Czabotar, P.E, Colman, P.M. | 登録日 | 2006-10-19 | 公開日 | 2007-03-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights into the degradation of Mcl-1 induced by BH3 domains. Proc.Natl.Acad.Sci.USA, 104, 2007
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2NO6
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![BU of 2no6 by Molmil](/molmil-images/mine/2no6) | C4S dCK variant of dCK in complex with FTC+ADP | 分子名称: | 4-AMINO-5-FLUORO-1-[(2R,5S)-2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase | 著者 | Sabini, E, Hazra, S, Konrad, M, Burley, S.K, Lavie, A. | 登録日 | 2006-10-25 | 公開日 | 2007-07-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides. J.Med.Chem., 50, 2007
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6FQ2
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![BU of 6fq2 by Molmil](/molmil-images/mine/6fq2) | Structure of minimal sequence for left -handed G-quadruplex formation | 分子名称: | DNA (5'-D(*GP*TP*GP*GP*TP*GP*GP*TP*GP*GP*TP*G)-3'), POTASSIUM ION | 著者 | Schmitt, E, Mechulam, Y, Phan, A.T, Heddi, B, Bakalar, B. | 登録日 | 2018-02-13 | 公開日 | 2018-12-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | A Minimal Sequence for Left-Handed G-Quadruplex Formation. Angew. Chem. Int. Ed. Engl., 58, 2019
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2IVJ
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![BU of 2ivj by Molmil](/molmil-images/mine/2ivj) | Isopenicillin N Synthase From Aspergillus Nidulans (Anaerobic Ac- cyclopropylglycine Fe Complex) | 分子名称: | D-(L-A-AMINOADIPOYL)-L-CYSTEINYL-D-CYCLOPROPYLGLYCINE, FE (II) ION, ISOPENICILLIN N SYNTHETASE, ... | 著者 | Howard-Jones, A.R, Elkins, J.M, Clifton, I.J, Roach, P.L, Adlington, R.M, Baldwin, J.E, Rutledge, P.J. | 登録日 | 2006-06-13 | 公開日 | 2007-04-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Interactions of Isopenicillin N Synthase with Cyclopropyl-Containing Substrate Analogues Reveal New Mechanistic Insight. Biochemistry, 46, 2007
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1FNT
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![BU of 1fnt by Molmil](/molmil-images/mine/1fnt) | CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST IN COMPLEX WITH THE PROTEASOME ACTIVATOR PA26 FROM TRYPANOSOME BRUCEI AT 3.2 ANGSTROMS RESOLUTION | 分子名称: | MAGNESIUM ION, PROTEASOME ACTIVATOR PROTEIN PA26, PROTEASOME COMPONENT C1, ... | 著者 | Whitby, F.G, Masters, E, Kramer, L, Knowlton, J.R, Yao, Y, Wang, C.C, Hill, C.P. | 登録日 | 2000-08-23 | 公開日 | 2001-04-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the activation of 20S proteasomes by 11S regulators. Nature, 408, 2000
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3K9S
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![BU of 3k9s by Molmil](/molmil-images/mine/3k9s) | |
2VWW
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![BU of 2vww by Molmil](/molmil-images/mine/2vww) | ephB4 kinase domain inhibitor complex | 分子名称: | EPHRIN TYPE-B RECEPTOR 4, N'-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3,4,5- TRIMETHOXYPHENYL)PYRIMIDINE-2,4-DIAMINE | 著者 | Read, J, Brassington, C.A, Green, I, McCall, E.J, Valentine, A.L, Barratt, D, Leach, A.G, Kettle, J.G. | 登録日 | 2008-06-27 | 公開日 | 2008-07-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Inhibitors of the Tyrosine Kinase Ephb4. Part 1: Structure-Based Design and Optimization of a Series of 2,4-Bis-Anilinopyrimidines Bioorg.Med.Chem.Lett., 18, 2008
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2VY2
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![BU of 2vy2 by Molmil](/molmil-images/mine/2vy2) | Structure of LEAFY transcription factor from Arabidopsis thaliana in complex with DNA from AG-I promoter | 分子名称: | 5'-D(*AP*TP*TP*TP*AP*AP*TP*CP*CP*AP *AP*TP*GP*GP*TP*TP*AP*CP*AP*A)-3', PROTEIN LEAFY | 著者 | Hames, C, Ptchelkine, D, Grimm, C, Thevenon, E, Moyroud, E, Gerard, F, Martiel, J.L, Benlloch, R, Parcy, F, Muller, C.W. | 登録日 | 2008-07-16 | 公開日 | 2008-09-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis for Leafy Floral Switch Function and Similarity with Helix-Turn-Helix Proteins. Embo J., 27, 2008
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3JYT
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![BU of 3jyt by Molmil](/molmil-images/mine/3jyt) | K65R mutant HIV-1 reverse transcriptase cross-linked to DS-DNA and complexed with DATP as the incoming nucleotide substrate | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(DDG))-3'), DNA (5'-D(*A*TP*GP*GP*TP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), ... | 著者 | Das, K, Arnold, E. | 登録日 | 2009-09-22 | 公開日 | 2009-10-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis for the role of the K65r mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance. J.Biol.Chem., 284, 2009
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8FY3
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![BU of 8fy3 by Molmil](/molmil-images/mine/8fy3) | Structure of NOT1:NOT10:NOT11 module of the human CCR4-NOT complex | 分子名称: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | 著者 | Lea, S.M, Deme, J.C, Raisch, T, Pekovic, F, Valkov, E. | 登録日 | 2023-01-25 | 公開日 | 2023-07-26 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Structure and assembly of the NOT10:11 module of the CCR4-NOT complex. Commun Biol, 6, 2023
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2NOA
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![BU of 2noa by Molmil](/molmil-images/mine/2noa) | The structure of deoxycytidine kinase complexed with lamivudine and ADP. | 分子名称: | 4-AMINO-1-[(2R,5S)-2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase | 著者 | Sabini, E, Lavie, A. | 登録日 | 2006-10-25 | 公開日 | 2007-02-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase. Nucleic Acids Res., 35, 2007
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3J4U
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![BU of 3j4u by Molmil](/molmil-images/mine/3j4u) | A new topology of the HK97-like fold revealed in Bordetella bacteriophage: non-covalent chainmail secured by jellyrolls | 分子名称: | cementing protein, major capsid protein | 著者 | Zhang, X, Guo, H, Jin, L, Czornyj, E, Hodes, A, Hui, W.H, Nieh, A.W, Miller, J.F, Zhou, Z.H. | 登録日 | 2013-10-09 | 公開日 | 2013-12-25 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 A resolution. Elife, 2, 2013
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2VSP
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![BU of 2vsp by Molmil](/molmil-images/mine/2vsp) | Crystal structure of the fourth PDZ domain of PDZ domain-containing protein 1 | 分子名称: | PDZ DOMAIN-CONTAINING PROTEIN 1 | 著者 | Yue, W.W, Shafqat, N, Pilka, E.S, Johansson, C, Murray, J.W, Elkins, J, Roos, A, Cooper, C, Phillips, C, Salah, E, von Delft, F, Doyle, D, Edwards, A, Wikstrom, M, Arrowsmith, C, Bountra, C, Oppermann, U. | 登録日 | 2008-04-28 | 公開日 | 2009-03-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Crystal Structure of the Fourth Pdz Domain of Pdz Domain-Containing Protein 1 To be Published
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4H8Z
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![BU of 4h8z by Molmil](/molmil-images/mine/4h8z) | Radiation damage study of lysozyme - 0.21 MGy | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C | 著者 | Sutton, K.A, Snell, E.H. | 登録日 | 2012-09-24 | 公開日 | 2013-05-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.1998 Å) | 主引用文献 | Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies. Acta Crystallogr.,Sect.D, 69, 2013
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4H9E
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![BU of 4h9e by Molmil](/molmil-images/mine/4h9e) | Radiation damage study of lysozyme - 0.84 MGy | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C | 著者 | Sutton, K.A, Snell, E.H. | 登録日 | 2012-09-24 | 公開日 | 2013-05-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.1998 Å) | 主引用文献 | Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies. Acta Crystallogr.,Sect.D, 69, 2013
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2N4P
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![BU of 2n4p by Molmil](/molmil-images/mine/2n4p) | Solution structure of the n-terminal domain of tdp-43 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Mompean, M, Romano, V, Pantoja-Uceda, D, Stuani, C, Baralle, F, Buratti, E, Laurents, D.V. | 登録日 | 2015-06-26 | 公開日 | 2016-01-20 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The TDP-43 N-terminal domain structure at high resolution. Febs J., 283, 2016
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