4LCJ
CtBP2 in complex with substrate MTOB
Summary for 4LCJ
Entry DOI | 10.2210/pdb4lcj/pdb |
Related | 4LCE |
Descriptor | C-terminal-binding protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-(METHYLSULFANYL)-2-OXOBUTANOIC ACID, ... (4 entities in total) |
Functional Keywords | rossmann fold, transcriptional corepressor, d-isomer 2-hydroxyacid dehydrogenase, oxidoreductase-oxidoreductase substrate complex, oxidoreductase/oxidoreductase substrate |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : P56545 |
Total number of polymer chains | 8 |
Total formula weight | 314651.46 |
Authors | Hilbert, B.J.,Schiffer, C.A.,Royer Jr., W.E. (deposition date: 2013-06-21, release date: 2014-03-19, Last modification date: 2024-02-28) |
Primary citation | Hilbert, B.J.,Grossmann, S.R.,Schiffer, C.A.,Royer, W.E. Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design. Febs Lett., 588:1743-1748, 2014 Cited by PubMed: 24657618DOI: 10.1016/j.febslet.2014.03.026 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.86 Å) |
Structure validation
Download full validation report