1FNT

CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST IN COMPLEX WITH THE PROTEASOME ACTIVATOR PA26 FROM TRYPANOSOME BRUCEI AT 3.2 ANGSTROMS RESOLUTION

Summary for 1FNT

Related1ryp 1avo
DescriptorPROTEASOME COMPONENT C7-ALPHA, PROTEASOME COMPONENT Y7, PROTEASOME COMPONENT Y13, ... (16 entities in total)
Functional Keywordsmulticatalytic proteinase, 20s proteasome, protein degradation, antigen processing, protease, proteasome activator, cell adhesion, interferon induction, hydrolase-hydrolase activator complex, hydrolase/hydrolase activator
Biological sourceSaccharomyces cerevisiae (baker's yeast)
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Cellular locationCytoplasm  P21243 P23639 P23638 P40303 P32379 P40302 P21242 P38624 P25043 P25451 P22141 P30656 P23724 P30657
Total number of polymer chains42
Total molecular weight1079359.66
Authors
Whitby, F.G.,Masters, E.,Kramer, L.,Knowlton, J.R.,Yao, Y.,Wang, C.C.,Hill, C.P. (deposition date: 2000-08-23, release date: 2001-04-11, Last modification date: 2018-01-31)
Primary citation
Whitby, F.G.,Masters, E.I.,Kramer, L.,Knowlton, J.R.,Yao, Y.,Wang, C.C.,Hill, C.P.
Structural basis for the activation of 20S proteasomes by 11S regulators.
Nature, 408:115-120, 2000
PubMed: 11081519 (PDB entries with the same primary citation)
DOI: 10.1038/35040607
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.2 Å)
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Structure validation

RfreeRamachandran outliersSidechain outliersRSRZ outliers 0.322 5.5% 13.2% 3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02