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7WS4
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Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ...
著者Guo, H, Gao, Y, Ji, X, Yang, H.
登録日2022-01-28
公開日2022-06-01
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of Omicron spike complexes and implications for neutralizing antibody development.
Cell Rep, 39, 2022
7WS5
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Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ...
著者Guo, H, Gao, Y, Ji, X, Yang, H.
登録日2022-01-28
公開日2022-06-01
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of Omicron spike complexes and implications for neutralizing antibody development.
Cell Rep, 39, 2022
7WS1
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BU of 7ws1 by Molmil
Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ...
著者Guo, H, Gao, Y, Ji, X, Yang, H.
登録日2022-01-28
公開日2022-06-01
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of Omicron spike complexes and implications for neutralizing antibody development.
Cell Rep, 39, 2022
8DZI
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BU of 8dzi by Molmil
Structure of SARS-CoV-2 Omicron BA.1.1.529 Spike trimer with one RBD down in complex with the Fab fragment of human neutralizing antibody MB.02
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Hu, Y, Xiong, Y.
登録日2022-08-07
公開日2022-08-31
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Function and Cryo-EM structures of broadly potent bispecific antibodies against multiple SARS-CoV-2 Omicron sublineages.
Signal Transduct Target Ther, 8, 2023
5JOR
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BU of 5jor by Molmil
Crystal structure of unbound anti-glycan antibody Fab14.22 at 2.2 A
分子名称: Fab 14.22 light chain, Fab14.22 heavy chain, GLYCEROL, ...
著者Sarkar, A, Irimia, A, Teyton, L, Wilson, I.A.
登録日2016-05-02
公開日2017-03-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.206 Å)
主引用文献T cells control the generation of nanomolar-affinity anti-glycan antibodies.
J. Clin. Invest., 127, 2017
7SG5
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BU of 7sg5 by Molmil
Structure of PfCSP peptide 21 with antibody CIS43_Var2
分子名称: CIS43_Var2 Fab Heavy chain, CIS43_Var2 Fab Light chain, GLYCEROL, ...
著者Tripathi, P, Kwong, P.D.
登録日2021-10-05
公開日2022-06-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Highly protective antimalarial antibodies via precision library generation and yeast display screening.
J.Exp.Med., 219, 2022
7SG6
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BU of 7sg6 by Molmil
Structure of PfCSP peptide 21 with antibody CIS43_Var10
分子名称: CIS43_Var10 Fab Heavy chain, CIS43_Var10 Fab Light chain, GLYCEROL, ...
著者Tripathi, P, Kwong, P.D.
登録日2021-10-05
公開日2022-06-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Highly protective antimalarial antibodies via precision library generation and yeast display screening.
J.Exp.Med., 219, 2022
6AVU
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BU of 6avu by Molmil
Human alpha-V beta-3 Integrin (open conformation) in complex with the therapeutic antibody LM609
分子名称: Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ...
著者Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D.
登録日2017-09-04
公開日2017-11-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (35 Å)
主引用文献The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
7X8P
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BU of 7x8p by Molmil
Frizzled 2 CRD in complex with pF7_A5 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody pF7_A5 Fab, Heavy chain, ...
著者Ge, Q, Wang, Q.
登録日2022-03-14
公開日2023-02-01
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献An epitope-directed selection strategy facilitating the identification of Frizzled receptor selective antibodies.
Structure, 31, 2023
5JOP
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BU of 5jop by Molmil
Crystal structure of anti-glycan antibody Fab14.22 in complex with Streptococcus pneumoniae serotype 14 tetrasaccharide at 1.75 A
分子名称: Fab 14.22 light chain, Fab14.22 heavy chain, GLYCEROL, ...
著者Sarkar, A, Irimia, A, Teyton, L, Wilson, I.A.
登録日2016-05-02
公開日2017-03-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献T cells control the generation of nanomolar-affinity anti-glycan antibodies.
J. Clin. Invest., 127, 2017
7BBJ
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BU of 7bbj by Molmil
CD73 in complex with the humanized antagonistic antibody mAb19
分子名称: 5'-nucleotidase, MAGNESIUM ION, ZINC ION, ...
著者Boettcher, J, Han, F.
登録日2020-12-17
公開日2021-12-29
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献A Novel Antagonistic CD73 Antibody for Inhibition of the Immunosuppressive Adenosine Pathway.
Mol.Cancer Ther., 20, 2021
7FEI
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BU of 7fei by Molmil
Complex of FMDV A/WH/CHA/09 and bovine neutralizing scFv antibody R55
分子名称: Capsid protein VP0, IG HEAVY CHAIN VARIABLE REGION, IG LAMDA CHAIN VARIABLE REGION
著者He, Y, Li, K, Lou, Z.
登録日2021-07-20
公開日2021-09-29
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization.
J.Virol., 95, 2021
8DEQ
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BU of 8deq by Molmil
Cryo-EM local refinement of antibody SKV09 in complex with VEEV alphavirus spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SKV09 Fab Heavy Chain, SKV09 Fab Light Chain, ...
著者Casner, R.G, Verardi, R, Roederer, M, Shapiro, L.
登録日2022-06-21
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8DER
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BU of 8der by Molmil
Cryo-EM local refinement of antibody SKV16 in complex with VEEV alphavirus spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SKV16 Fab Heavy Chain, ...
著者Casner, R.G, Verardi, R, Roederer, M, Shapiro, L.
登録日2022-06-21
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
5VXJ
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BU of 5vxj by Molmil
2.50 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JMK-E3
分子名称: Invasin IpaD, single-domain antibody JMK-E3
著者Barta, M.L, Lovell, S, Battaile, K.P, Picking, W.D, Picking, W.L.
登録日2017-05-23
公開日2017-08-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献2.50 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JMK-E3
To Be Published
8SAK
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BU of 8sak by Molmil
BtCoV-422 in complex with neutralizing antibody JC57-11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者McFadden, E, McLellan, J.S.
登録日2023-04-01
公開日2023-10-04
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.
Sci Transl Med, 15, 2023
5VXL
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2.80 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JPS-G3
分子名称: Invasin IpaD, single-domain antibody JPS-G3
著者Barta, M.L, Lovell, S, Battaile, K.P, Picking, W.D, Picking, W.L.
登録日2017-05-23
公開日2017-08-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献2.80 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JPS-G3
To Be Published
5VXK
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BU of 5vxk by Molmil
2.55 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JMK-H2
分子名称: Invasin IpaD, single-domain antibody JMK-H2
著者Barta, M.L, Lovell, S, Battaile, K.P, Picking, W.D, Picking, W.L.
登録日2017-05-23
公開日2017-08-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献2.55 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JMK-H2
To Be Published
5VXM
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BU of 5vxm by Molmil
2.05 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody 20ipaD
分子名称: Invasin IpaD, Single-domain antibody 20ipaD
著者Barta, M.L, Lovell, S, Battaile, K.P, Picking, W.D, Picking, W.L.
登録日2017-05-23
公開日2017-08-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献2.05 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody 20ipaD
To Be Published
1ZVH
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BU of 1zvh by Molmil
Crystal structure of the VHH domain D2-L24 in complex with hen egg white lysozyme
分子名称: Immunoglobulin heavy chain antibody variable domain, Lysozyme C
著者De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L.
登録日2005-06-02
公開日2006-04-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
7VSW
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BU of 7vsw by Molmil
Crystal structure of a Fab-like fragment of anti-mesothelin antibody
分子名称: heavy chain, light chain
著者Yang, Z, Ying, T.
登録日2021-10-27
公開日2021-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Design of a Novel Fab-Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use.
Small Methods, 6, 2022
7VSU
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BU of 7vsu by Molmil
Crystal structure of Fab fragment of anti-mesothelin antibody
分子名称: Light chain, heavy chain
著者Yang, Z, Ying, T.
登録日2021-10-27
公開日2021-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Design of a Novel Fab-Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use.
Small Methods, 6, 2022
5XS7
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BU of 5xs7 by Molmil
Structure of Coxsackievirus A6 (CVA6) virus A-particle in complex with the neutralizing antibody fragment 1D5
分子名称: Genome polyprotein, Heavy chain of Fab 1D5, Light chain of Fab 1D5
著者Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Li, S.W, Cheng, T.
登録日2017-06-12
公開日2017-09-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
Nat Commun, 8, 2017
7E39
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BU of 7e39 by Molmil
SARS-CoV-2 spike in complex with the Ab4 neutralizing antibody (State 3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Ab4, Light Chain of Ab4, ...
著者Liu, C.
登録日2021-02-08
公開日2021-09-01
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Three epitope-distinct human antibodies from RenMab mice neutralize SARS-CoV-2 and cooperatively minimize the escape of mutants.
Cell Discov, 7, 2021
7E3C
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BU of 7e3c by Molmil
SARS-CoV-2 spike in complex with the Ab1 neutralizing antibody (focused refinement on Fab-RBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Ab1, Light chain of Ab1, ...
著者Liu, C.
登録日2021-02-08
公開日2021-09-01
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Three epitope-distinct human antibodies from RenMab mice neutralize SARS-CoV-2 and cooperatively minimize the escape of mutants.
Cell Discov, 7, 2021

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件を2024-07-24に公開中

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