7BBJ

CD73 in complex with the humanized antagonistic antibody mAb19

Summary for 7BBJ

• Entry DOI: 10.2210/pdb7bbj/pdb
• Descriptor: 5'-nucleotidase, heavy chain mAb19, light chain mAB19, ... (6 entities in total)
• Functional Keywords: antibody complex, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 216423.55

Authors

Boettcher, J.,Han, F. (deposition date: 2020-12-17, release date: 2021-12-29, Last modification date: 2024-01-31)

• Primary citation: Wurm, M.,Schaaf, O.,Reutner, K.,Ganesan, R.,Mostbock, S.,Pelster, C.,Bottcher, J.,de Andrade Pereira, B.,Taubert, C.,Alt, I.,Serna, G.,Auguste, A.,Stadermann, K.B.,Delic, D.,Han, F.,Capdevila, J.,Nuciforo, P.G.,Kroe-Barrett, R.,Adam, P.J.,Vogt, A.B.,Hofmann, I.; A Novel Antagonistic CD73 Antibody for Inhibition of the Immunosuppressive Adenosine Pathway.; Mol.Cancer Ther., 20:2250-2261, 2021; PubMed: 34482286; DOI: 10.1158/1535-7163.MCT-21-0107

Experimental method

X-RAY DIFFRACTION (2.72 Å)