6QLF
 
 | | Structure of inner kinetochore CCAN complex with mask1 | | 分子名称: | Inner kinetochore subunit AME1, Inner kinetochore subunit CHL4, Inner kinetochore subunit CTF19, ... | | 著者 | Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D. | | 登録日 | 2019-01-31 | | 公開日 | 2019-10-02 | | 最終更新日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
|
|
5J9U
 | | Crystal structure of the NuA4 core complex | | 分子名称: | Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, Enhancer of polycomb-like protein 1, ... | | 著者 | Chen, Z.C, Xu, P. | | 登録日 | 2016-04-11 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
|
|
5J9W
 | | Crystal structure of the NuA4 core complex | | 分子名称: | ACETYL COENZYME *A, Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, ... | | 著者 | Chen, Z.C, Xu, P. | | 登録日 | 2016-04-11 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
|
|
5J9T
 | | Crystal structure of the NuA4 core complex | | 分子名称: | Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, Enhancer of polycomb-like protein 1, ... | | 著者 | Chen, Z.C, Xu, P. | | 登録日 | 2016-04-11 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
|
|
5VEY
 | | Solution NMR structure of histone H2A-H2B mono-ubiquitylated at H2A Lys15 in complex with RNF169 (653-708) | | 分子名称: | E3 ubiquitin-protein ligase RNF169, Histone H2B type 1-J,Histone H2A type 1-B/E, Polyubiquitin-B | | 著者 | Hu, Q, Botuyan, M.V, Cui, G, Mer, G. | | 登録日 | 2017-04-06 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-10-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18.
Mol. Cell, 66, 2017
|
|
4O1L
 | | Human Adenosine Kinase in complex with inhibitor | | 分子名称: | 5-ethynyl-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Adenosine kinase, MAGNESIUM ION | | 著者 | Brynda, J, Dostal, J, Pichova, I, Hodcek, M. | | 登録日 | 2013-12-16 | | 公開日 | 2014-11-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides
J.Med.Chem., 57, 2014
|
|
5VF0
 | |
5X21
 | | Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM) | | 分子名称: | (1S)-1,4-anhydro-5-[(N-carbamimidoylglycyl-N~2~-hydroxy-L-glutaminyl)amino]-5-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Zhang, Y, Ebright, R. | | 登録日 | 2017-01-29 | | 公開日 | 2017-07-05 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (3.323 Å) | | 主引用文献 | Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase.
Cell, 169, 2017
|
|
2YHG
 | | Ab initio phasing of a nucleoside hydrolase-related hypothetical protein from Saccharophagus degradans that is associated with carbohydrate metabolism | | 分子名称: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | 著者 | Hehemann, J.H, Marsters, C, Boraston, A.B. | | 登録日 | 2011-04-30 | | 公開日 | 2011-08-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | | 主引用文献 | Ab initio phasing of a nucleoside hydrolase-related hypothetical protein from Saccharophagus degradans that is associated with carbohydrate metabolism.
Proteins, 79, 2011
|
|
5HMZ
 | | Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 23 | | 分子名称: | 5-(5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl)-4-methoxy-2-methyl-N-(methylsulfonyl)benzamide, RNA-directed RNA polymerase NS5, ZINC ION | | 著者 | Noble, C.G. | | 登録日 | 2016-01-17 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design
J.Med.Chem., 59, 2016
|
|
5HMX
 | | Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 10 | | 分子名称: | 2,2'-(5-(thiophen-2-yl)-1,3-phenylene)diacetic acid, RNA-directed RNA polymerase NS5, ZINC ION | | 著者 | Noble, C.G. | | 登録日 | 2016-01-17 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design
J.Med.Chem., 59, 2016
|
|
5HMY
 | | Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 15 | | 分子名称: | 2,2'-(5-(5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl)-1,3-phenylene)diacetic acid, RNA-directed RNA polymerase NS5, ZINC ION | | 著者 | Noble, C.G. | | 登録日 | 2016-01-17 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design.
J.Med.Chem., 59, 2016
|
|
5HMW
 | | Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 5 | | 分子名称: | 2,2'-biphenyl-3,5-diyldiacetic acid, RNA-directed RNA polymerase NS5, ZINC ION | | 著者 | Noble, C.G. | | 登録日 | 2016-01-17 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design
J.Med.Chem., 59, 2016
|
|
4O1G
 | | MTB adenosine kinase in complex with gamma-Thio-ATP | | 分子名称: | Adenosine kinase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, SODIUM ION | | 著者 | Dostal, J, Brynda, J, Hocek, M, Pichova, I. | | 登録日 | 2013-12-15 | | 公開日 | 2014-11-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides
J.Med.Chem., 57, 2014
|
|
6NRA
 | | hTRiC-hPFD Class1 (No PFD) | | 分子名称: | T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... | | 著者 | Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | | 登録日 | 2019-01-23 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cell, 177, 2019
|
|
6NRC
 | | hTRiC-hPFD Class3 | | 分子名称: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | | 著者 | Gestaut, D, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | | 登録日 | 2019-01-23 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | | 主引用文献 | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cell, 177, 2019
|
|
9GBZ
 | | 5'-lobe of the substrate-bound U11 snRNP | | 分子名称: | P120-5'SS, U11 snRNA, U11/U12 small nuclear ribonucleoprotein 25 kDa protein, ... | | 著者 | Zhao, J, Galej, W.P. | | 登録日 | 2024-07-31 | | 公開日 | 2025-02-05 | | 最終更新日 | 2025-02-19 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of 5' splice site recognition by the minor spliceosome.
Mol.Cell, 85, 2025
|
|
5HN0
 | | Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 4 | | 分子名称: | (6-hydroxybiphenyl-3-yl)acetic acid, RNA-directed RNA polymerase NS5, ZINC ION | | 著者 | Noble, C.G. | | 登録日 | 2016-01-17 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design.
J.Med.Chem., 59, 2016
|
|
6NR9
 | | hTRiC-hPFD Class5 | | 分子名称: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | | 著者 | Gestaut, D, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | | 登録日 | 2019-01-23 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (8.5 Å) | | 主引用文献 | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cell, 177, 2019
|
|
6NRD
 | | hTRiC-hPFD Class4 | | 分子名称: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | | 著者 | Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | | 登録日 | 2019-01-23 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (8.2 Å) | | 主引用文献 | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cell, 177, 2019
|
|
6NR8
 | | hTRiC-hPFD Class6 | | 分子名称: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | | 著者 | Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | | 登録日 | 2019-01-23 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cell, 177, 2019
|
|
7QP3
 | | Pseudogymnoascus pannorum M36 protease without the propeptide | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wilkens, C, Qiu, J, Meyer, A.S, Morth, J.P. | | 登録日 | 2021-12-30 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Phaeosphaeria nodorum M36 protease without the propeptide
To Be Published
|
|
5ZWN
 | | Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 angstrom (Part II: U1 snRNP region) | | 分子名称: | 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Pre-mRNA-splicing ATP-dependent RNA helicase PRP28, ... | | 著者 | Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y. | | 登録日 | 2018-05-16 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
|
|
6NRB
 | | hTRiC-hPFD Class2 | | 分子名称: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | | 著者 | Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | | 登録日 | 2019-01-23 | | 公開日 | 2019-06-19 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (8.7 Å) | | 主引用文献 | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cell, 177, 2019
|
|
9CG9
 | | Cryo-EM structure of an HMGB1 box bound to nucleosome at SHL-2 | | 分子名称: | High mobility group protein B1, Histone H2A type 1, Histone H2B, ... | | 著者 | Chio, U.S, Saunders, H.S, Narlikar, G.J, Cheng, Y. | | 登録日 | 2024-06-28 | | 公開日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Competition between HMGB1 and H1 on nucleosomes tunes dynamics within condensed chromatin
To Be Published
|
|
