4O1G

MTB adenosine kinase in complex with gamma-Thio-ATP

Summary for 4O1G

Entry DOI	10.2210/pdb4o1g/pdb
Descriptor	Adenosine kinase, SODIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... (4 entities in total)
Functional Keywords	adenosine kinase, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	35050.19
Authors	Dostal, J.,Brynda, J.,Hocek, M.,Pichova, I. (deposition date: 2013-12-15, release date: 2014-11-26, Last modification date: 2024-03-20)
Primary citation	Snasel, J.,Naus, P.,Dostal, J.,Hnizda, A.,Fanfrlik, J.,Brynda, J.,Bourderioux, A.,Dusek, M.,Dvorakova, H.,Stolarikova, J.,Zabranska, H.,Pohl, R.,Konecny, P.,Dzubak, P.,Votruba, I.,Hajduch, M.,Rezacova, P.,Veverka, V.,Hocek, M.,Pichova, I. Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides J.Med.Chem., 57:8268-8279, 2014 Cited by PubMed: 25259627 DOI: 10.1021/jm500497v PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation